[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100636023":3},{"organization":4,"armGroups":7,"interventions":7,"overallOfficials":7,"centralContacts":7,"locations":7,"responsibleParty":8,"collaborators":7,"id":12,"slug":13,"hasResults":14,"nctId":15,"briefTitle":16,"officialTitle":17,"acronym":18,"eligibilityCriteria":19,"healthyVolunteers":14,"sex":20,"minAge":21,"maxAge":7,"enrollmentInfo":22,"targetDuration":7,"studyType":25,"phases":7,"briefSummary":26,"conditions":27,"keywords":30,"overallStatus":36,"whyStopped":7,"lastUpdateSubmitDate":37,"lastUpdatePostDateStruct":38,"startDateStruct":41,"completionDateStruct":42,"leadSponsor":44,"locationsCount":7},{"fullName":5,"class":6},"Beijing Tsinghua Chang Gung Hospital","OTHER",null,{"type":9,"investigatorFullName":10,"investigatorTitle":11,"investigatorAffiliation":5,"oldNameTitle":7,"oldOrganization":7},"PRINCIPAL_INVESTIGATOR","Weiwei Wu","Chief Physician","100636023","3d-eit-for-diagnosis-and-monitoring-of-pulmonary-embolism-100636023",false,"NCT07560293","3D-EIT for Diagnosis and Monitoring of Pulmonary Embolism","Prospective Validation of Three-Dimensional Electrical Impedance Tomography for the Diagnosis, Risk Stratification, and Longitudinal Monitoring of Pulmonary Embolism","TIDE-PE","Inclusion Criteria:\n\n* Age 18 years or older\n* Body mass index (BMI) less than 50 kg\u002Fm²\n* Able to provide written informed consent\n* first episode of pulmonary embolism confirmed by CT pulmonary angiography (CTPA), with or without CT venography (CTV)\n\nExclusion Criteria:\n\n* Previous diagnosis of pulmonary embolism\n* Pregnancy\n* Thoracic deformity or chest wall abnormality preventing proper placement of the EIT electrode belt\n* Contraindications to EIT use, including implantable cardioverter-defibrillator, pacemaker, implanted pumps, or chest wounds limiting electrode placement\n* Concurrent participation in another interventional clinical study Hemodynamic instability requiring emergency intervention that precludes completion of the EIT examination (PE cohort only)\n* Any other condition judged by the investigator to make the participant unsuitable for study participation","ALL","18 Years",{"count":23,"type":24},115,"ESTIMATED","OBSERVATIONAL","This prospective observational study aims to validate three-dimensional electrical impedance tomography (3D-EIT) as a non-invasive bedside tool for the diagnosis and longitudinal monitoring of pulmonary embolism (PE). The study will include a PE cohort and a control cohort without PE or venous thromboembolism (VTE). Using algorithms that separate ventilation and perfusion signals, 3D-EIT-derived indices, including the Matching Index (MI), Dead Space Index (DI), and Shunt Index (SI), will be quantified. The diagnostic performance of MI and DI will be evaluated against computed tomography pulmonary angiography (CTPA), and their associations with PE severity, risk stratification, and treatment response will be explored. This study is expected to support the clinical translation of 3D-EIT as a radiation-free bedside functional imaging tool for PE management.",[28,29],"Pulmonary Embolism (Diagnosis)","Venous Thromboembolism (VTE)",[31,32,33,34,35],"Pulmonary Embolism","Electrical Impedance Tomography","Three-dimensional Imaging","Lung Perfusion","Ventilation-Perfusion Mismatch","NOT_YET_RECRUITING","2026-04-24",{"date":39,"type":40},"2026-05-01","ACTUAL",{"date":39,"type":24},{"date":43,"type":24},"2028-05-01",{"name":5,"class":6}]