[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100531914":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":10,"centralContacts":35,"locations":43,"responsibleParty":62,"collaborators":10,"id":65,"slug":66,"hasResults":67,"nctId":68,"briefTitle":69,"officialTitle":70,"acronym":10,"eligibilityCriteria":71,"healthyVolunteers":67,"sex":72,"minAge":73,"maxAge":74,"enrollmentInfo":75,"targetDuration":10,"studyType":78,"phases":10,"briefSummary":79,"conditions":80,"keywords":83,"overallStatus":46,"whyStopped":10,"lastUpdateSubmitDate":84,"lastUpdatePostDateStruct":85,"startDateStruct":88,"completionDateStruct":90,"leadSponsor":92,"locationsCount":93},{"fullName":5,"class":6},"Shengjing Hospital","OTHER",[8,15],{"label":9,"type":10,"description":11,"interventionNames":12},"Experimental group",null,"Experimental group was set to develop the novel non-invasive model for virtual HVPG using 3d-MRE",[13,14],"Device: 3D-MRE","Device: HVPG",{"label":16,"type":10,"description":17,"interventionNames":18},"Control group","Control group was set to develop the novel non-invasive model for virtual HVPG using 2d-MRE",[19,14],"Device: 2D-MRE",[21,26,30,33],{"type":22,"name":23,"description":24,"armGroupLabels":25,"otherNames":10},"DEVICE","3D-MRE","All imaging studies were performed by using a 3.0-T MRI system (Signa HDx, GE Healthcare) with an eight-channel phasedarray body coil.",[9],{"type":22,"name":27,"description":28,"armGroupLabels":29,"otherNames":10},"HVPG","HVPG measurements are performed by well-trained interventional radiologists in accordance with standard operating procedures",[9],{"type":22,"name":31,"description":24,"armGroupLabels":32,"otherNames":10},"2D-MRE",[16],{"type":22,"name":27,"description":28,"armGroupLabels":34,"otherNames":10},[16],[36,40],{"name":37,"role":38,"phone":10,"phoneExt":10,"email":39},"Yu Shi","CONTACT","18940259980@163.com",{"name":41,"role":38,"phone":10,"phoneExt":10,"email":42},"Zhiying Wang","wangzhiying990816@163.com",[44],{"facility":45,"status":46,"city":47,"state":48,"zip":49,"country":50,"countryCode":51,"cosmosGeoPoint":52,"geoPoint":57,"contacts":58},"Shengjing Hospital of China Medical University","RECRUITING","Shenyang","Liaoning","110004","China","CN",{"type":53,"coordinates":54},"Point",[55,56],123.43278,41.79222,{"lat":56,"lon":55},[59],{"name":60,"role":38,"phone":61,"phoneExt":10,"email":39},"Yu Shi, MD","+8618940259980",{"type":63,"investigatorFullName":37,"investigatorTitle":64,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"PRINCIPAL_INVESTIGATOR","Deputy director of department of radology","100531914","3d-mre-and-2d-mre-for-assessing-cirrhosis-and-portal-hypertension-100531914",false,"NCT06205992","3D-MRE and 2D-MRE for Assessing Cirrhosis and Portal Hypertension","Three-dimensional MR Elastography and Two-dimensional MR Elastography for Assessing Cirrhosis and Portal Hypertension：A Prospective Multicenter Study","Inclusion Criteria:\n\n1. age \\> 18 years old\n2. confirmed cirrhosis (laboratory, imaging and clinical symptoms)\n3. with 3D-MRE and 2D-MRE within 1 month prior to HVPG measurement\n4. written informed consent\n\nExclusion Criteria:\n\n1. any previous liver or spleen surgery\n2. liver cancer; chronic acute liver failure\n3. acute portal hypertension\n4. unreliable HVPG, 3D-MRE or 2D-MRE results due to technical reasons\n5. with liver interventional therapy between HVPG and MRE","ALL","18 Years","75 Years",{"count":76,"type":77},100,"ESTIMATED","OBSERVATIONAL","How to construct a novel, non-invasive, accurate, and convenient method to achieve prediction of hepatic venous pressure gradient (HVPG) is an important general problem in the management of portal hypertension in cirrhosis. We plan to compare the ability of three demensional-magnetic resonance elastography (3D-MRE) to two demensional-magnetic resonance elastography (2D-MRE) to establish a risk stratification system and perform tailored management for portal hypertension in cirrhosis.",[81,82],"Cirrhosis","Liver Portal Hypertension",[23,31,27],"2026-02-05",{"date":86,"type":87},"2026-02-09","ACTUAL",{"date":89,"type":87},"2022-08-16",{"date":91,"type":77},"2026-12-01",{"name":5,"class":6},1]