[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100616598":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":24,"centralContacts":29,"locations":24,"responsibleParty":35,"collaborators":24,"id":39,"slug":40,"hasResults":41,"nctId":42,"briefTitle":43,"officialTitle":44,"acronym":24,"eligibilityCriteria":45,"healthyVolunteers":41,"sex":46,"minAge":47,"maxAge":24,"enrollmentInfo":48,"targetDuration":24,"studyType":51,"phases":52,"briefSummary":54,"conditions":55,"keywords":58,"overallStatus":63,"whyStopped":24,"lastUpdateSubmitDate":64,"lastUpdatePostDateStruct":65,"startDateStruct":68,"completionDateStruct":70,"leadSponsor":72,"locationsCount":24},{"fullName":5,"class":6},"University of Salamanca","OTHER",[8,15],{"label":9,"type":10,"description":11,"interventionNames":12},"Exercise group","EXPERIMENTAL","The investigators propose a 8 vs 12-week intervention with therapeutic strength exercise in patients with colorectal cancer who are receiving chemotherapy treatment.",[13,14],"Other: Exercise","Other: Physical activity recommendations",{"label":16,"type":10,"description":17,"interventionNames":18},"Control group","They will be provided with clear and concrete recommendations of activities for the user to perform the rest of the days of the week in order to increase their level of physical activity and increase weekly metabolic expenditure.",[14],[20,25],{"type":6,"name":21,"description":22,"armGroupLabels":23,"otherNames":24},"Exercise","There will be 2 weekly sessions of 50 minutes, always guided by a physiotherapist, with the following distribution:\n\n1.- Warm-up: 15 minutes of global exercises of strength and resistance, focusing on the areas that are going to be worked as a priority in that session.\n\nStrength training: 6 to 8 strength exercises of large muscle groups. The approximate duration will be 25 minutes.\n\n3.- Cool down \u002F cool down: Combination of breathing exercises and stretching, 10 minutes.\n\nMonitoring with activity bracelets.",[9],null,{"type":6,"name":26,"description":27,"armGroupLabels":28,"otherNames":24},"Physical activity recommendations","They will be provided with a physical activity plan to be followed on a weekly basis.",[16,9],[30],{"name":31,"role":32,"phone":33,"phoneExt":24,"email":34},"Carlos Martin Sanchez, PhD","CONTACT","+34923294500","carlos_ms@usal.es",{"type":36,"investigatorFullName":37,"investigatorTitle":38,"investigatorAffiliation":5,"oldNameTitle":24,"oldOrganization":24},"PRINCIPAL_INVESTIGATOR","CARLOS MARTIN SANCHEZ","PhD","100616598","8-weeks-vs-12-weeks-physical-exercise-programmes-in-colorectal-cancer-patients-100616598",false,"NCT07307690","8 Weeks vs 12 Weeks Physical Exercise Programmes in Colorectal Cancer Patients","Comparison of the Effectiveness of 8-week vs 12-week Physical Exercise Programmes in Patients With Colorectal Cancer","Inclusion Criteria:\n\n* People diagnosed with colorectal cancer and who are receiving chemotherapy treatment.\n* Sedentary people who have not performed physical activity in the last 8 weeks.\n* Ability to understand the evaluation tests and the performance of the exercises.\n* Presence of XXX symptoms (If we focus on neuropathy, it should be inclusion criteria).\n* Voluntary participation in the study.\n\nExclusion Criteria:\n\n\\- Present contraindication\u002Fs for physical exercise (musculoskeletal diseases, severe cardiovascular disease, bone metastases,...).","ALL","18 Years",{"count":49,"type":50},50,"ESTIMATED","INTERVENTIONAL",[53],"NA","Chemotherapy is a cornerstone in the treatment of colon cancer; however, its effects extend beyond malignant cells. Because chemotherapeutic agents target rapidly dividing cells, they can also damage healthy tissues, resulting in a range of adverse effects. Among the most prevalent is peripheral neuropathy, a disorder of the peripheral nervous system characterized by symptoms such as tingling, numbness, pain, and weakness in the extremities.\n\nChemotherapy-induced peripheral neuropathy poses a significant challenge for patients with colon cancer, as it further compromises quality of life during an already demanding phase of treatment. Damage to sensory and motor nerves interferes with the ability to perform daily activities and diminishes physical capacity, thereby intensifying both the physical and psychological burden associated with the disease.\n\nNevertheless, certain interventions may help mitigate these negative effects, with physical exercise emerging as a particularly promising strategy. Although it may appear counterintuitive, regular physical activity has been shown to exert beneficial effects on peripheral neuropathy. Exercise enhances blood circulation, supports the regeneration of damaged peripheral nerves, and helps reduce neuropathic pain and discomfort, ultimately improving functional performance.\n\nIt is important to emphasize that exercise interventions should be individually tailored and conducted under appropriate medical supervision. Consequently, the integration of chemotherapy with a carefully designed exercise program represents a comprehensive approach to managing both the disease and its treatment-related side effects, contributing to an improved quality of life for patients with colon cancer throughout their recovery process.",[56,57],"Oncology","Chemotherapy-Induced Peripheral Neuropathy",[21,59,60,61,62],"Cancer","Colorectal cancer","wellbeing","Mental health","NOT_YET_RECRUITING","2025-12-30",{"date":66,"type":67},"2026-01-06","ACTUAL",{"date":69,"type":50},"2026-01-01",{"date":71,"type":50},"2026-06-01",{"name":5,"class":6}]