[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100285237":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":33,"centralContacts":38,"locations":45,"responsibleParty":78,"collaborators":43,"id":81,"slug":82,"hasResults":83,"nctId":84,"briefTitle":85,"officialTitle":86,"acronym":43,"eligibilityCriteria":87,"healthyVolunteers":83,"sex":88,"minAge":89,"maxAge":43,"enrollmentInfo":90,"targetDuration":43,"studyType":93,"phases":94,"briefSummary":96,"conditions":97,"keywords":99,"overallStatus":48,"whyStopped":43,"lastUpdateSubmitDate":101,"lastUpdatePostDateStruct":102,"startDateStruct":105,"completionDateStruct":107,"leadSponsor":109,"locationsCount":110},{"fullName":5,"class":6},"Xinhua Hospital, Shanghai Jiao Tong University School of Medicine","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"99Tc-MDP","EXPERIMENTAL","99Tc-MDP group:15mg in 100ml normal saline intravenously dripped every twice a week for 5 weeks, every 1weeks for 10 weeks, every 2weeks for 10 weeks, every 1 month for 6 months.",[13],"Drug: 99Tc-MDP",{"label":15,"type":16,"description":17,"interventionNames":18},"celecoxib","ACTIVE_COMPARATOR","celecoxib capsule 200mg qd by mouth.",[19],"Drug: Celecoxib",[21,27],{"type":22,"name":9,"description":23,"armGroupLabels":24,"otherNames":25},"DRUG","99Tc-MDP 15mg in 100ml normal saline intravenously dripped every twice a week for 5 weeks, every 1weeks for 10 weeks, every 2weeks for 10 weeks, every 1 month for 6 months.",[9],[26],"Yunke",{"type":22,"name":28,"description":29,"armGroupLabels":30,"otherNames":31},"Celecoxib","Celecoxib capsule 200mg qd by mouth.",[15],[32],"Xile Bao",[34],{"name":35,"affiliation":36,"role":37},"Zhongwei Lv, MD","The 10th Hospital, Tongji University","PRINCIPAL_INVESTIGATOR",[39],{"name":40,"role":41,"phone":42,"phoneExt":43,"email":44},"Chao Ma, MD","CONTACT","+86-021-25078593",null,"mc_7419@hotmail.com",[46],{"facility":47,"status":48,"city":49,"state":50,"zip":51,"country":52,"countryCode":53,"cosmosGeoPoint":54,"geoPoint":59,"contacts":60},"Department of Nuclear Medicine, Tenth People's Hospital of Tongji University","RECRUITING","Shanghai","Shanghai Municipality","200072","China","CN",{"type":55,"coordinates":56},"Point",[57,58],121.45806,31.22222,{"lat":58,"lon":57},[61,63,66,69,71,73,75,77],{"name":40,"role":41,"phone":62,"phoneExt":43,"email":44},"+86021-66302075",{"name":64,"role":41,"phone":62,"phoneExt":43,"email":65},"Haidong Cai, MD","caihdong@163.com",{"name":67,"role":68,"phone":43,"phoneExt":43,"email":43},"Yanlei Huo, BA","SUB_INVESTIGATOR",{"name":70,"role":37,"phone":43,"phoneExt":43,"email":43},"Jianhao Huo, BA",{"name":72,"role":68,"phone":43,"phoneExt":43,"email":43},"Danyang Wang, BA",{"name":74,"role":68,"phone":43,"phoneExt":43,"email":43},"Jing Xu, MD",{"name":76,"role":37,"phone":43,"phoneExt":43,"email":43},"Kejia Gao, BA",{"name":64,"role":68,"phone":43,"phoneExt":43,"email":43},{"type":37,"investigatorFullName":79,"investigatorTitle":80,"investigatorAffiliation":5,"oldNameTitle":43,"oldOrganization":43},"Chao Ma","Professor","100285237","99tc-mdp-treatment-for-knee-osteoarthritis-100285237",false,"NCT02993029","99Tc-MDP Treatment for Knee Osteoarthritis","99Tc-MDP Versus Celecoxib Treatment in Patients With Knee Osteoarthritis","Inclusion Criteria:\n\n1. Participants with painful osteoarthritis;\n2. The standard uptake value (SUV) of OA related knee greater than 10 on 18F- sodium fluoride bone scan;\n3. Participants voluntarily participate in the trial, and signed the informed consent.\n\nExclusion Criteria:\n\n1. Knee joint replacement;\n2. Inflammatory arthritis or joint infection of knee;\n3. Nervous joint disease;\n4. Fracture of joint;\n5. Gout arthritis of the knee;\n6. Traumatic arthritis.","ALL","40 Years",{"count":91,"type":92},40,"ESTIMATED","INTERVENTIONAL",[95],"NA","Osteoarthritis (OA) of knee is the most common form of arthritis in the world1e, and it has received growing attention in the society because of the increase of old age population, disabled people, and medical expenses from this disease. 99Tc-MDP is effective for rheumatoid arthritis. Therefore, the investigators try to investigate the effects of 99Tc-MDP treatment in patients with osteoarthritis of knee as compared with celecoxib.",[98],"Treatment Outcome",[9,100,15],"osteoarthritis","2026-04-22",{"date":103,"type":104},"2026-04-28","ACTUAL",{"date":106,"type":104},"2017-09-01",{"date":108,"type":92},"2027-12-30",{"name":5,"class":6},1]