[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100630867":3},{"organization":4,"armGroups":7,"interventions":22,"overallOfficials":41,"centralContacts":46,"locations":51,"responsibleParty":67,"collaborators":69,"id":73,"slug":74,"hasResults":75,"nctId":76,"briefTitle":77,"officialTitle":78,"acronym":28,"eligibilityCriteria":79,"healthyVolunteers":80,"sex":81,"minAge":82,"maxAge":28,"enrollmentInfo":83,"targetDuration":28,"studyType":86,"phases":87,"briefSummary":89,"conditions":90,"keywords":28,"overallStatus":92,"whyStopped":28,"lastUpdateSubmitDate":93,"lastUpdatePostDateStruct":94,"startDateStruct":97,"completionDateStruct":99,"leadSponsor":101,"locationsCount":102},{"fullName":5,"class":6},"Fred Hutchinson Cancer Center","OTHER",[8,16],{"label":9,"type":10,"description":11,"interventionNames":12},"Arm I (Actify! A app)","EXPERIMENTAL","Participants use the Actify! app, which helps users identify personal values and meaningful activities, prompts users to schedule and complete meaningful activities, visualizes progress towards meeting activity and smoking-related goals, and provides tailored messages, resources, daily tips, personalized feedback, inspirational messages, and user stories, for 8 weeks on study.",[13,14,15],"Behavioral: Smartphone app-based Intervention (Actify! A app)","Other: Health Promotion and Education","Other: Survey Administration",{"label":17,"type":18,"description":19,"interventionNames":20},"Arm II (Actify! B app)","ACTIVE_COMPARATOR","Participants use an app, which contains quit advice, tools for tracking smokefree days, progress and cravings, guidance on preparing to quit, managing cravings and withdrawal, recovering from slips, and a mood management feature, for 8 weeks on study.",[21,14,15],"Behavioral: Smartphone app-based Intervention (Actify! B app)",[23,29,33,37],{"type":24,"name":25,"description":26,"armGroupLabels":27,"otherNames":28},"BEHAVIORAL","Smartphone app-based Intervention (Actify! A app)","Use Actify! A app",[9],null,{"type":24,"name":30,"description":31,"armGroupLabels":32,"otherNames":28},"Smartphone app-based Intervention (Actify! B app)","Use Actify! B app",[17],{"type":6,"name":34,"description":35,"armGroupLabels":36,"otherNames":28},"Health Promotion and Education","Receive motivational messages and smoking cessation information via text messages",[9,17],{"type":6,"name":38,"description":39,"armGroupLabels":40,"otherNames":28},"Survey Administration","Ancillary studies",[9,17],[42],{"name":43,"affiliation":44,"role":45},"Jaimee Heffner, PhD","Fred Hutch\u002FUniversity of Washington Cancer Consortium","PRINCIPAL_INVESTIGATOR",[47],{"name":43,"role":48,"phone":49,"phoneExt":28,"email":50},"CONTACT","206-667-7314","jheffner@fredhutch.org",[52],{"facility":44,"status":28,"city":53,"state":54,"zip":55,"country":56,"countryCode":57,"cosmosGeoPoint":58,"geoPoint":63,"contacts":64},"Seattle","Washington","98109","United States","US",{"type":59,"coordinates":60},"Point",[61,62],-122.33207,47.60621,{"lat":62,"lon":61},[65,66],{"name":43,"role":48,"phone":49,"phoneExt":28,"email":50},{"name":43,"role":45,"phone":28,"phoneExt":28,"email":28},{"type":68,"investigatorFullName":28,"investigatorTitle":28,"investigatorAffiliation":28,"oldNameTitle":28,"oldOrganization":28},"SPONSOR",[70],{"name":71,"class":72},"National Institute on Drug Abuse (NIDA)","NIH","100630867","a-behavioral-application-for-improving-smoking-cessation-among-smokers-100630867",false,"NCT07493252","A Behavioral Application for Improving Smoking Cessation Among Smokers","Actify! An mHealth Mood Management Tool to Improve Population-Level Smoking Cessation","Inclusion Criteria:\n\n* Age 18 or older\n* Currently smoke, averaging at least 5 cigarettes\u002Fday for the last 30 days\n* Interested in quitting smoking in the next 30 days\n* Experience downloading and using one or more apps on their smartphone\n* Either screens negative for depression (Patient Health Questionnaire - 9 item \\[PHQ-9\\] score 0-4; n = 906) or screens positive for mild to moderately severe current depressive symptoms (PHQ-9 score 5-19; n = 906)\n* Willing and able to complete all study activities and to receive compensation by mail\n* Comfortable reading and writing in English\n* Have a mobile data plan and\u002For access to WiFi to support the use of the assigned app\n* Reside in the United States (US)\n* Willing to provide information for an emergency contact in case of serious concerns about the participant's physical or mental health\n\nExclusion Criteria:\n\n* Self-report of currently receiving behavioral treatment for depression (e.g., psychotherapy or counseling, web- or app-based interventions); current use of pharmacotherapy for depression or for other mental health conditions that are not otherwise excluded is allowable (e.g., benzodiazepines, anticonvulsants, opioid agonists, antipsychotics)\n* Severe depression (PHQ-9 ≥ 20)\n* Current suicidal ideation reported on the PHQ-9\n* History of a suicide attempt\n* Self-reported lifetime diagnosis of bipolar disorder, schizophrenia, schizoaffective disorder, antisocial personality disorder, or borderline personality disorder; or self-reported lifetime diagnosis of an alcohol or drug use disorder with use of the substance(s) in the past 30 days\n* Currently receiving other smoking cessation treatments, including pharmacotherapies (nicotine replacement therapy, bupropion, or varenicline) and behavioral interventions (e.g. quitline counseling, other digital health programs), but excluding electronic (e)-cigarettes\u002Fvaping\n* Previous use of the QuitGuide program\n* Employees\u002Ffamily of investigator or study center\n* Member of the same household as another participant\n* Woman who is pregnant or breastfeeding, or planning to become pregnant\n* Having a Google voice number as their primary phone number (due to association with fraudulent study entry attempts in our previous work)\n* Currently incarcerated\n* Participated in earlier studies to develop the Actify! app",true,"ALL","18 Years",{"count":84,"type":85},1812,"ESTIMATED","INTERVENTIONAL",[88],"NA","This clinical trial compares two smartphone applications, called Actify! (A \\& B) for improving smoking cessation outcomes in individuals who smoke. Actify! A is an app grounded in behavioral activation therapy, an evidence-based treatment for depression that can also be used to modify health behaviors such as smoking. The Actify! B app provides evidence-based tobacco cessation strategies based on current clinical guidelines.",[91],"Cigarette Smoking-Related Carcinoma","NOT_YET_RECRUITING","2026-06-01",{"date":95,"type":96},"2026-06-03","ACTUAL",{"date":98,"type":85},"2026-08-01",{"date":100,"type":85},"2029-07-31",{"name":5,"class":6},1]