[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100611824":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":30,"centralContacts":35,"locations":26,"responsibleParty":41,"collaborators":26,"id":45,"slug":46,"hasResults":47,"nctId":48,"briefTitle":49,"officialTitle":50,"acronym":26,"eligibilityCriteria":51,"healthyVolunteers":47,"sex":52,"minAge":53,"maxAge":54,"enrollmentInfo":55,"targetDuration":26,"studyType":58,"phases":59,"briefSummary":61,"conditions":62,"keywords":26,"overallStatus":65,"whyStopped":26,"lastUpdateSubmitDate":66,"lastUpdatePostDateStruct":67,"startDateStruct":70,"completionDateStruct":72,"leadSponsor":74,"locationsCount":26},{"fullName":5,"class":6},"Southern Medical University, China","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Control Arm: Conventional Functional Electrical Stimulation","PLACEBO_COMPARATOR","Participants will receive functional electrical stimulation (FES) administered in a conventional, non-synergy-based mode. This arm serves as an active comparator.",[13],"Device: Traditional functional electrical stimulation",{"label":15,"type":16,"description":17,"interventionNames":18},"Experimental Arm: Muscle Synergy-Based Functional Electrical Stimulation","EXPERIMENTAL","Participants will receive a novel functional electrical stimulation (FES) intervention guided by a real-time, muscle synergy-based algorithm.",[19],"Device: Collaborative Functional Electrical Stimulation",[21,27],{"type":22,"name":23,"description":24,"armGroupLabels":25,"otherNames":26},"DEVICE","Collaborative Functional Electrical Stimulation","Functional electrical stimulation based on muscle synergy",[15],null,{"type":22,"name":28,"description":28,"armGroupLabels":29,"otherNames":26},"Traditional functional electrical stimulation",[9],[31],{"name":32,"affiliation":33,"role":34},"Xuan Chen","Southern Medical University","STUDY_CHAIR",[36],{"name":37,"role":38,"phone":39,"phoneExt":26,"email":40},"Chen Xuan Chen Xuan,Ph.D.","CONTACT","+8619731548492","2415919580@qq.com",{"type":42,"investigatorFullName":43,"investigatorTitle":44,"investigatorAffiliation":5,"oldNameTitle":26,"oldOrganization":26},"SPONSOR_INVESTIGATOR","Chen Xuan","graduate student","100611824","a-biomechanical-study-of-collaborative-fes-on-lower-limb-motor-function-in-the-elderly-100611824",false,"NCT07245602","A Biomechanical Study of Collaborative FES on Lower Limb Motor Function in the Elderly","Biomechanical Study on the Improvement of Lower Limb Motor Function in the Elderly Through Collaborative Functional Electrical Stimulation","Inclusion Criteria:\n\n* Must be aged between 65 and 75 years, inclusive.\n* Must be community-dwelling.\n* Must be able to ambulate independently, with or without the use of an assistive device (e.g., a cane or walker).\n* Must be capable of understanding and following study-related instructions and procedures.\n* Must provide voluntary written informed consent to participate in the study.\n\nExclusion Criteria:\n\n* Diagnosis of a significant neurological disorder, including but not limited to stroke, Parkinson's disease, or multiple sclerosis.\n* Presence of a severe musculoskeletal condition that would interfere with movement tasks, such as severe osteoarthritis or osteoporosis.\n* History of lower limb joint replacement surgery within the last 6 months.\n* Cognitive impairment, as indicated by a Mini-Mental State Examination (MMSE) score of less than 24.\n* Presence of any implanted electronic medical device, such as a cardiac pacemaker or defibrillator.\n* Any skin disease, open wound, infection, or malignancy at the intended sites of electrical stimulation.\n* Diagnosis of a severe and\u002For uncontrolled cardiovascular condition (e.g., unstable angina, recent myocardial infarction).\n* Inability to stand independently without support for at least 3 minutes.","ALL","65 Years","75 Years",{"count":56,"type":57},30,"ESTIMATED","INTERVENTIONAL",[60],"NA","This study will first conduct a precise assessment of the differences in muscle coordination among the elderly through muscle synergy analysis; then, based on this, it will extract abnormal synergy patterns and muscle activation patterns, and reconstruct the intervention's synergy modules to fit the intervention electrostimulation curve; finally, electrical stimulation interventions will be carried out on different elderly individuals under two conditions: sitting and walking, to evaluate the intervention effects and analyze the biomechanical mechanisms of its effectiveness.",[63,64],"Muscle Fatigue (C23.888.592.612.612)","Muscle Weakness or Atrophy","NOT_YET_RECRUITING","2025-11-17",{"date":68,"type":69},"2025-11-24","ACTUAL",{"date":71,"type":57},"2025-11-30",{"date":73,"type":57},"2027-05-01",{"name":43,"class":6}]