[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100574075":3},{"organization":4,"armGroups":7,"interventions":26,"overallOfficials":43,"centralContacts":48,"locations":55,"responsibleParty":116,"collaborators":42,"id":119,"slug":120,"hasResults":121,"nctId":122,"briefTitle":123,"officialTitle":124,"acronym":33,"eligibilityCriteria":125,"healthyVolunteers":126,"sex":127,"minAge":128,"maxAge":42,"enrollmentInfo":129,"targetDuration":42,"studyType":132,"phases":133,"briefSummary":135,"conditions":136,"keywords":138,"overallStatus":75,"whyStopped":42,"lastUpdateSubmitDate":142,"lastUpdatePostDateStruct":143,"startDateStruct":146,"completionDateStruct":148,"leadSponsor":150,"locationsCount":151},{"fullName":5,"class":6},"Taipei Medical University","OTHER",[8,14,20],{"label":9,"type":10,"description":11,"interventionNames":12},"Caregiver-Assisted Rehabilitation with Strategy Training (CAR-ST)","EXPERIMENTAL","Trained therapists visit each participant once or twice weekly for 60 minutes. The program consists of 10 therapist-guided sessions over a maximum of 6 weeks and includes the following active ingredients: self-selected activity-based goals, dynamic performance analysis, global strategy (\"Goal-PlanDo-Check\"), massed practice, variable practice, increasing task difficulty, explicit and implicit feedback, guided discovery, action observation, and social interaction.",[13],"Behavioral: Caregiver-Assisted Rehabilitation with Strategy Training",{"label":15,"type":16,"description":17,"interventionNames":18},"Strategy Training","ACTIVE_COMPARATOR","Participants assigned to the ST group receive a protocol similar to CAR-ST, with the distinction that their caregivers are not asked to co-participate in the intervention, and they are not instructed (by the research therapist) to provide assistance during at-home practice.",[19],"Behavioral: Strategy Training",{"label":21,"type":22,"description":23,"interventionNames":24},"Education","PLACEBO_COMPARATOR","In this arm, participants receive a dose-matched intervention with 10 visits by well-trained research therapists through face-to-face talks (primary approach), video conference, or telephone calls. Sessions focus on instruction on general information regarding stroke and rehabilitation, and a summary of participants' condition and progression is provided for each visit.",[25],"Behavioral: Education",[27,34,39],{"type":28,"name":29,"description":30,"armGroupLabels":31,"otherNames":32},"BEHAVIORAL","Caregiver-Assisted Rehabilitation with Strategy Training","CAR-ST is a home-based rehabilitation that guides both stroke survivors and their caregivers to implement strategy training for addressing daily activity limitations after stroke. The caregiver, as an active partner, not only supervises the participant but also co-participates in the practice. Caregivers are instructed on when and how to provide assistance during task practice, using physical, verbal, or visual guidance. As the participant's performance improves, the caregiver is empowered to motivate them to exert greater efforts, encouraging higher repetitions, longer durations of the same task, and an increased level of difficulty.",[9],[33],"CAR-ST",{"type":28,"name":15,"description":35,"armGroupLabels":36,"otherNames":37},"Compared to CAR-ST, ST is a home-based rehabilitation that guides stroke survivors only to implement strategy training for addressing daily activity limitations after stroke.",[15],[38],"ST",{"type":28,"name":21,"description":40,"armGroupLabels":41,"otherNames":42},"Stroke-related information and knowledge that includes stroke subtypes and their etiology, risk factors of primary and secondary stroke, healthy lifestyles, common sequala, and adaptive skills for impaired functions are provided.",[21],null,[44],{"name":45,"affiliation":46,"role":47},"Feng-Heng Chang, ScD","Graduate Institute of Injury Prevention and Control, Taipei Medical University","PRINCIPAL_INVESTIGATOR",[49],{"name":50,"role":51,"phone":52,"phoneExt":53,"email":54},"Chang, ScD","CONTACT","+886-2-66202589","16040","ipc@tmu.edu.tw",[56,73,84,96,106],{"facility":57,"status":58,"city":59,"state":42,"zip":60,"country":61,"countryCode":62,"cosmosGeoPoint":63,"geoPoint":68,"contacts":69},"Taipei Tzu Chi Hospital","NOT_YET_RECRUITING","New Taipei City","231","Taiwan","TW",{"type":64,"coordinates":65},"Point",[66,67],121.45703,25.06199,{"lat":67,"lon":66},[70],{"name":71,"role":51,"phone":42,"phoneExt":42,"email":72},"Chu, MD","m513108006@tmu.edu.tw",{"facility":74,"status":75,"city":59,"state":42,"zip":76,"country":61,"countryCode":62,"cosmosGeoPoint":77,"geoPoint":79,"contacts":80},"Taipei Medical University-Shuang Ho Hospital,Ministry of Health and Welfare","RECRUITING","235",{"type":64,"coordinates":78},[66,67],{"lat":67,"lon":66},[81],{"name":82,"role":51,"phone":42,"phoneExt":42,"email":83},"Chen, MD","b8601084@tmu.edu.tw",{"facility":85,"status":58,"city":86,"state":42,"zip":87,"country":61,"countryCode":62,"cosmosGeoPoint":88,"geoPoint":92,"contacts":93},"National Taiwan University Hospital","Taipei","100",{"type":64,"coordinates":89},[90,91],121.52639,25.05306,{"lat":91,"lon":90},[94],{"name":82,"role":51,"phone":42,"phoneExt":42,"email":95},"wenshiang@gmail.com",{"facility":97,"status":75,"city":86,"state":42,"zip":98,"country":61,"countryCode":62,"cosmosGeoPoint":99,"geoPoint":101,"contacts":102},"Taipei Medical University Hospital","110",{"type":64,"coordinates":100},[90,91],{"lat":91,"lon":90},[103],{"name":104,"role":51,"phone":42,"phoneExt":42,"email":105},"Kang, MD","jhk@tmu.edu.tw",{"facility":107,"status":75,"city":86,"state":42,"zip":108,"country":61,"countryCode":62,"cosmosGeoPoint":109,"geoPoint":111,"contacts":112},"Taipei Municipal Wanfang Hospital","116",{"type":64,"coordinates":110},[90,91],{"lat":91,"lon":90},[113],{"name":114,"role":51,"phone":42,"phoneExt":42,"email":115},"Lin, MD","solin1103@tmu.edu.tw",{"type":47,"investigatorFullName":117,"investigatorTitle":118,"investigatorAffiliation":5,"oldNameTitle":42,"oldOrganization":42},"Feng-Hang Chang","Professor","100574075","a-caregiver-assisted-rehabilitation-with-strategy-training-car-st-for-stroke-patients-100574075",false,"NCT06754566","A Caregiver-Assisted Rehabilitation With Strategy Training (CAR-ST) for Stroke Patients","A Caregiver-Assisted Rehabilitation With Strategy Training (CAR-ST) for Stroke Patients With Functional Limitations: A MultiCenter, 3-Arm Randomized Trial","Inclusion Criteria:\n\n* Being willing to provide informed consent\n* Diagnosis with ischemic and\u002For hemorrhagic stroke\n* Modified Rankin Scale (mRS) ranges from 2 to 4\n* Rehabilitation frequency less than 3 days per week\n* Having a healthy caregiver\n\nExclusion Criteria:\n\n* Undergoing palliative care\n* Major diseases or severe conditions influencing study participation, such as global aphasia, dementia, multiple organ failure, immobilization due to fracture, etc\n* Moderate post-stroke cognitive impairment, with Montreal Cognitive Assessment score \\\u003C22\n* Pre-stroke mRS \\> 1\n* Participating in other interventional study concurrently.",true,"ALL","18 Years",{"count":130,"type":131},261,"ESTIMATED","INTERVENTIONAL",[134],"NA","The goal of this randomized controlled trial is to examine if involving the caregivers in the strategy training (i.e. caregiver-assisted rehabilitation with strategy training, CAR-ST) works to improve activity functions in community-dwelling adults after stroke. The main questions it aims to answer are:\n\nDoes CAR-ST and strategy training alone lead to greater improvements in activity performance among stroke survivors relative to the control intervention with education? Does CAR-ST outperform strategy training alone in the efficacy of activity outcomes? Do the activity effects of CAR-ST transfer to the impairment and participation domains of outcomes?\n\nResearchers will compare the efficacy of the CAR-ST intervention against strategy training alone or control intervention (education program) to see if caregivers contribute to post-stroke functional improvements.\n\nParticipants will:\n\n* receive CAR-ST, strategy training only, or an education program 1 to 2 sessions per week until finishing 10 sessions.\n* be assessed clinical outcomes at 4 times: pre-intervention, post-intervention, 3-month, and 6-month follow-up.",[137],"Stroke",[137,139,140,141],"Caregiver-assisted rehabilitation","Strategy training","Activity limitations","2025-02-13",{"date":144,"type":145},"2025-02-17","ACTUAL",{"date":147,"type":145},"2025-01-17",{"date":149,"type":131},"2028-12-31",{"name":5,"class":6},5]