[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100524133":3},{"organization":4,"armGroups":7,"interventions":7,"overallOfficials":8,"centralContacts":13,"locations":19,"responsibleParty":38,"collaborators":7,"id":41,"slug":42,"hasResults":43,"nctId":44,"briefTitle":45,"officialTitle":45,"acronym":7,"eligibilityCriteria":46,"healthyVolunteers":43,"sex":47,"minAge":48,"maxAge":49,"enrollmentInfo":50,"targetDuration":53,"studyType":54,"phases":7,"briefSummary":55,"conditions":56,"keywords":58,"overallStatus":21,"whyStopped":7,"lastUpdateSubmitDate":64,"lastUpdatePostDateStruct":65,"startDateStruct":68,"completionDateStruct":70,"leadSponsor":72,"locationsCount":73},{"fullName":5,"class":6},"Shanghai First Maternity and Infant Hospital","OTHER",null,[9],{"name":10,"affiliation":11,"role":12},"Luming Sun, Doctor","Department of Fetal Medicine, Shanghai First Maternity and Infant Hospital","PRINCIPAL_INVESTIGATOR",[14],{"name":15,"role":16,"phone":17,"phoneExt":7,"email":18},"Jianping Chen, Master","CONTACT","+86 13916159565","urchin_chen@163.com",[20],{"facility":5,"status":21,"city":22,"state":23,"zip":24,"country":25,"countryCode":26,"cosmosGeoPoint":27,"geoPoint":32,"contacts":33},"RECRUITING","Shanghai","Shanghai Municipality","201204","China","CN",{"type":28,"coordinates":29},"Point",[30,31],121.45806,31.22222,{"lat":31,"lon":30},[34],{"name":35,"role":16,"phone":36,"phoneExt":7,"email":37},"Luming Sun, MD; PhD","021-20261151","luming_sun@163.com",{"type":12,"investigatorFullName":39,"investigatorTitle":40,"investigatorAffiliation":5,"oldNameTitle":7,"oldOrganization":7},"Luming Sun","Professor","100524133","a-cohort-of-maternal-vascular-malperfusion-related-fgr-comvmfgr-100524133",false,"NCT06104748","A Cohort of Maternal Vascular Malperfusion-related FGR (CoMVMFGR)","Inclusion Criteria:\n\n1.Singleton pregnancy 2. diagnosed as FGR according the delphi consensus:\n\n1. Early-onset FGR(\\\u003C32 weeks) Estimated fetal weight (EFW) or abdominal circumference (AC) \\\u003C 3rd; or EFW or AC \\\u003C 10th, combined with abnormal doppler, including uterine artery pulsatility index(UtA PI) \\>95th percentile, umbilical artery pulsatility index(UA PI) \\>95th percentile； or umbilical artery absent end-diastolic flow (UA-AEDF) or umbilical artery reversed end-diastolic flow(UA-REDF).\n2. Late-onset FGR(≥32 weeks) Estimated fetal weight (EFW) or abdominal circumference (AC) \\\u003C 3rd; or \\>2 of the following 3 criteria:\n\n   * EFW or AC \\\u003C10th percentile\n   * EFW or AC crossing percentiles\\>2 quartiles on growth percentiles\n   * CPR \\\u003C5th percentile or UA-Pl\\>95th percentile 3.provision of signed written informed consent.\n\nExclusion Criteria:\n\n* Fetus with definitive genetic disorders related to FGR, fetus with confirmed intrauterine infection (CMV, syphilis and etc.), fetus with structural anomalies\n* Incomplete information or absence of informed consent","FEMALE","18 Years","45 Years",{"count":51,"type":52},500,"ESTIMATED","2 Years","OBSERVATIONAL","Based on a precise diagnostic standard process, through a multicenter study, we will establish a cohort focusing on placenta-mediated fetal growth restriction (FGR). Long-term follow-up will be conducted to seek predictive indicators for short-term and long-term adverse outcomes of maternal vascular malperfusion-related FGR (MVM-FGR).",[57],"MVM-FGR",[59,60,61,62,63],"FGR","maternal vascular malperfusion","Doppler","placenta","etiologies","2024-06-06",{"date":66,"type":67},"2024-06-07","ACTUAL",{"date":69,"type":67},"2023-08-10",{"date":71,"type":52},"2025-12-30",{"name":5,"class":6},1]