[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100566899":3},{"organization":4,"armGroups":7,"interventions":17,"overallOfficials":27,"centralContacts":31,"locations":37,"responsibleParty":50,"collaborators":10,"id":52,"slug":53,"hasResults":54,"nctId":55,"briefTitle":56,"officialTitle":56,"acronym":57,"eligibilityCriteria":58,"healthyVolunteers":54,"sex":59,"minAge":60,"maxAge":61,"enrollmentInfo":62,"targetDuration":10,"studyType":65,"phases":10,"briefSummary":66,"conditions":67,"keywords":10,"overallStatus":39,"whyStopped":10,"lastUpdateSubmitDate":70,"lastUpdatePostDateStruct":71,"startDateStruct":74,"completionDateStruct":76,"leadSponsor":78,"locationsCount":79},{"fullName":5,"class":6},"China-Japan Friendship Hospital","OTHER",[8,14],{"label":9,"type":10,"description":10,"interventionNames":11},"Surgical group",null,[12,13],"Procedure: Bariatric surgery","Other: Non-surgical therapy",{"label":15,"type":10,"description":10,"interventionNames":16},"Non-surgical group",[13],[18,23],{"type":19,"name":20,"description":21,"armGroupLabels":22,"otherNames":10},"PROCEDURE","Bariatric surgery","Laparoscopic sleeve gastrectomy or laparoscopic gastric bypass based on β-cell function",[9],{"type":6,"name":24,"description":25,"armGroupLabels":26,"otherNames":10},"Non-surgical therapy","Diet management，exercise，metformin，GLP-1 receptor agonists and other drugs which can lose weight.",[15,9],[28],{"name":29,"affiliation":5,"role":30},"Hua Meng","PRINCIPAL_INVESTIGATOR",[32],{"name":33,"role":34,"phone":35,"phoneExt":10,"email":36},"Nianrong Zhang","CONTACT","+86 188 1048 8650","znrsd@163.com",[38],{"facility":5,"status":39,"city":40,"state":41,"zip":10,"country":42,"countryCode":43,"cosmosGeoPoint":44,"geoPoint":49,"contacts":10},"RECRUITING","Beijing","Beijing Municipality","China","CN",{"type":45,"coordinates":46},"Point",[47,48],116.39723,39.9075,{"lat":48,"lon":47},{"type":30,"investigatorFullName":29,"investigatorTitle":51,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"Director of the General Surgery Department & Obesity and Metabolic Disease Center of China-Japan Friendship Hospital","100566899","a-cohort-study-on-the-efficacy-of-bariatric-surgery-for-rapidly-progressing-diabetic-nephropathy-100566899",false,"NCT06661174","A Cohort Study on the Efficacy of Bariatric Surgery for Rapidly Progressing Diabetic Nephropathy","EBSDKD","Inclusion Criteria:\n\n* Age 18 to 65 years old;\n\n  * BMI\\>25Kg\u002Fm2 or abdominal obesity (i.e. waist circumference\\>90cm for men and\\>85cm for women);\n\n    * eGFR\\\u003C30ml\u002Fmin\u002F1.73m2 or urinary microalbumin≥300mg\u002Fg, eGFR\\\u003C60ml\u002Fmin\u002F1.73m2.\n\nExclusion Criteria:\n\n* Patients who are taking glucocorticoids;\n\n  * Combined with tumors; ③Combined with autoimmune diseases; ④Serum albumin\\\u003C25g\u002FL.","ALL","18 Years","65 Years",{"count":63,"type":64},100,"ESTIMATED","OBSERVATIONAL","Establish a cohort of diabetic kidney disease(DKD) patients with intensive weight loss treatment to evaluate the impact of intensive weight loss treatment on the renal prognosis of DKD and construct a prediction model for the improvement of renal outcomes after weight loss.",[68,69],"Bariatric Surgeries","Diabetic Nephropathy","2024-10-24",{"date":72,"type":73},"2024-10-28","ACTUAL",{"date":75,"type":73},"2023-10-01",{"date":77,"type":64},"2025-10-30",{"name":5,"class":6},1]