[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100595648":3},{"organization":4,"armGroups":7,"interventions":18,"overallOfficials":24,"centralContacts":28,"locations":34,"responsibleParty":51,"collaborators":24,"id":55,"slug":56,"hasResults":57,"nctId":58,"briefTitle":59,"officialTitle":60,"acronym":24,"eligibilityCriteria":61,"healthyVolunteers":57,"sex":62,"minAge":63,"maxAge":64,"enrollmentInfo":65,"targetDuration":24,"studyType":68,"phases":69,"briefSummary":71,"conditions":72,"keywords":24,"overallStatus":76,"whyStopped":24,"lastUpdateSubmitDate":77,"lastUpdatePostDateStruct":78,"startDateStruct":81,"completionDateStruct":83,"leadSponsor":85,"locationsCount":86},{"fullName":5,"class":6},"Cairo University","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Group A: weight-based formula group","ACTIVE_COMPARATOR","Children will receive spinal anesthesia according to the weight-based dosing calculation of Hyperbaric bupivacaine 0.5% as following: 0.4 mg\u002Fkg (0.08 ml\u002Fkg) for children weighing 5-15 kg or 0.3 mg\u002Fkg (0.06 ml\u002Fkg) for children weighing \\>15 kg",[13],"Procedure: Spinal Anesthesia with Bupivacaine",{"label":15,"type":10,"description":16,"interventionNames":17},"Group B: Age-based formula group","Children will receive spinal anesthesia according to the age-based dosing calculation of bupivacaine. Hyperbaric bupivacaine 0.5% will be calculated using Partha formula by dividing the child's age in years by 5. The resultant figure will be considered to be the dose of Bupivacaine in ml. If the number of months after the completion of a year in age is more than 6 months, the child's age will be noted to be the year older.",[13],[19,25],{"type":20,"name":21,"description":22,"armGroupLabels":23,"otherNames":24},"PROCEDURE","Spinal Anesthesia with Bupivacaine","Group A (n=30) will receive spinal anesthesia according to the weight-based dosing calculation of bupivacaine.",[9],null,{"type":20,"name":21,"description":26,"armGroupLabels":27,"otherNames":24},"Group B (n=30) will receive spinal anesthesia according to the age-based dosing calculation of bupivacaine.",[15],[29],{"name":30,"role":31,"phone":32,"phoneExt":24,"email":33},"Hany M.EH Mohammed, MD","CONTACT","+201003066806","oblfollower_2001@yahoo.com, hany.elhadi@kasralainy.edu.eg",[35],{"facility":36,"status":24,"city":37,"state":38,"zip":39,"country":40,"countryCode":41,"cosmosGeoPoint":42,"geoPoint":47,"contacts":48},"Abu Elreesh Pediatric Hospital","Cairo","Assida Zainab","12211","Egypt","EG",{"type":43,"coordinates":44},"Point",[45,46],31.24967,30.06263,{"lat":46,"lon":45},[49],{"name":50,"role":31,"phone":32,"phoneExt":24,"email":33},"Hany M. El-Hadi Mohammed, MD",{"type":52,"investigatorFullName":53,"investigatorTitle":54,"investigatorAffiliation":5,"oldNameTitle":24,"oldOrganization":24},"PRINCIPAL_INVESTIGATOR","Hany Mohammed El-Hadi Shoukat Mohammed","Assistant Professor","100595648","a-comparative-study-between-age-based-and-weight-based-bupivacaine-dosing-for-pediatric-spinal-anesthesia-in-children-undergoing-elective-infra-umbilical-surgeries-100595648",false,"NCT07035184","A Comparative Study Between Age-Based and Weight-Based Bupivacaine Dosing for Pediatric Spinal Anesthesia in Children Undergoing Elective Infra-Umbilical Surgeries","A Comparative Study Between Age-Based and Weight-Based Bupivacaine Dosing for Pediatric Spinal Anesthesia in Children Undergoing Elective Infra-Umbilical Surgeries: A Randomized Double-Blinded Controlled Trial","Inclusion Criteria:\n\n* Children aged 1-6 years\n\n  * Both genders.\n  * American Society of Anesthesiologists (ASA) physical status I or II.\n  * Elective infra-umbilical surgeries with anticipated duration ≤ 90 minutes.\n\nExclusion Criteria:\n\n* Guardian refusal.\n\n  * Children with significant congenital heart disease (e.g., septal defects requiring surgical intervention)\n  * Children with neuromuscular disorders or high intracranial pressure.\n  * Children with spinal deformities or morbid obesity (body mass index (BMI) above the 99th percentile).\n  * Children with a history or family history of coagulation disorders.\n  * Children with local infection at the site of skin puncture for spinal anesthesia.\n  * Children with known allergy to Bupivacaine.\n  * Surgeries requiring Trendelenburg or prone position.\n  * Unexpected prolongation of surgery \\> 90 minutes","ALL","1 Year","6 Years",{"count":66,"type":67},60,"ESTIMATED","INTERVENTIONAL",[70],"NA","This prospective randomized double-blinded controlled trial will include 60 pediatric patients aged 1 - 6 years old, both sexes, with American society of anesthesiologists (I and II) and undergoing elective infra-umbilical surgeries with anticipated duration ≤ 90 minutes. Patients will be randomly divided into two equal groups: Weight-based dosing (Group A) and age-based dosing group (Group B). Both groups will receive hyperbaric bupivacaine 0.5%. The aim of the study is to evaluate the effectiveness of using age based dosing of Bupivacaine compared with standard method of weight based dosing in pediatric spinal anesthesia.",[73,74,75],"Pediatrics","Spinal Aneshtesia","Infraumbilical Surgeries","NOT_YET_RECRUITING","2025-06-14",{"date":79,"type":80},"2025-06-25","ACTUAL",{"date":82,"type":67},"2025-08-01",{"date":84,"type":67},"2025-10-15",{"name":5,"class":6},1]