[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100582542":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":25,"centralContacts":30,"locations":40,"responsibleParty":53,"collaborators":25,"id":55,"slug":56,"hasResults":57,"nctId":58,"briefTitle":59,"officialTitle":60,"acronym":25,"eligibilityCriteria":61,"healthyVolunteers":57,"sex":62,"minAge":63,"maxAge":64,"enrollmentInfo":65,"targetDuration":25,"studyType":68,"phases":69,"briefSummary":71,"conditions":72,"keywords":75,"overallStatus":80,"whyStopped":25,"lastUpdateSubmitDate":81,"lastUpdatePostDateStruct":82,"startDateStruct":85,"completionDateStruct":87,"leadSponsor":89,"locationsCount":90},{"fullName":5,"class":6},"Ain Shams University","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Patients receiving combined ACB and IPACK blocks","ACTIVE_COMPARATOR","ultrasound guided block of saphenous nerve in adductor canal and block of articular branches of knee between the popliteal artery and the knee capsule (IPACK)",[13],"Drug: Nerve Block with bupivacaine 0.25%",{"label":15,"type":10,"description":16,"interventionNames":17},"Patients receiving combined ACB and GNB","ultrasound guided block of saphenous nerve in adductor canal and block of the three peri-knee nerve branches: the superior medial genicular nerve (SMGN), inferior medial genicular nerve (IMGN), and superior lateral genicular nerve (SLGN)",[18],"Drug: nerve block with bupivacaine 0.25%",[20,26],{"type":21,"name":22,"description":23,"armGroupLabels":24,"otherNames":25},"DRUG","nerve block with bupivacaine 0.25%","ultrasound guided adductor canal block and interspace between the popliteal artery and the knee capsule using bupivacaine 0.25%",[15],null,{"type":21,"name":27,"description":28,"armGroupLabels":29,"otherNames":25},"Nerve Block with bupivacaine 0.25%","ultrasound guided combined adductor canal block and genicular nerve block using bupivacaine 0.25%",[9],[31,36],{"name":32,"role":33,"phone":34,"phoneExt":25,"email":35},"Ahmed Fathy","CONTACT","+201204465766","drfathy_83@yahoo.com",{"name":37,"role":33,"phone":38,"phoneExt":25,"email":39},"Maha Salah Omar","+201007269331","mahata5deer@gmail.com",[41],{"facility":5,"status":25,"city":42,"state":25,"zip":25,"country":43,"countryCode":44,"cosmosGeoPoint":45,"geoPoint":50,"contacts":51},"Cairo","Egypt","EG",{"type":46,"coordinates":47},"Point",[48,49],31.24967,30.06263,{"lat":49,"lon":48},[52],{"name":32,"role":33,"phone":34,"phoneExt":25,"email":35},{"type":54,"investigatorFullName":25,"investigatorTitle":25,"investigatorAffiliation":25,"oldNameTitle":25,"oldOrganization":25},"SPONSOR","100582542","a-comparative-study-of-combined-adductor-canal-and-interspace-between-popliteal-artery-and-knee-capsule-versus-combined-adductor-canal-and-genicular-nerve-in-total-knee-arthroplasty-100582542",false,"NCT06864663","A Comparative Study of Combined Adductor Canal and Interspace Between Popliteal Artery and Knee Capsule Versus Combined Adductor Canal and Genicular Nerve in Total Knee Arthroplasty","A Comparative Study of Combined Ultrasound-Guided Adductor Canal Block and Interspace Between the Popliteal Artery and Capsule of the Knee (IPACK) Versus Combined Adductor Canal Block and Genicular Nerve Block Following Total Knee Arthroplasty","Inclusion Criteria:\n\n1. Patients American Society of anesthesiologists' physical status (ASA) I to III.\n2. Aged 18 to 70 years.\n3. Both sexes.\n4. Patients scheduled for total knee arthroplasty.\n\nExclusion Criteria:\n\n1. Patient refusal\n2. ASA physical status IV or more.\n3. Patients with known allergy to any of the study drugs.\n4. Infection at the site of injection.\n5. Patients with neuromuscular disease.\n6. Presence of any coagulopathy.\n7. Patients with history of any psychiatric or cognitive disorder.\n8. patient with previous knee surgery.\n9. BMI more than 40 kg\u002Fm2.","ALL","18 Years","70 Years",{"count":66,"type":67},70,"ESTIMATED","INTERVENTIONAL",[70],"NA","The aim of this study is to investigate the effectiveness of combined adductor canal block (ACB) with interspace between popliteal artery and the knee capsule (IPACK) versus combined ACB with genicular nerve block (GNB) for providing analgesia in knee arthroplasty. The investigators hypothesize that the analgesic efficacy of ACB combined with GNB will be non-inferior to that of ACB combined with IPACK. Additionally, the investigators aim to assess whether the combination of ACB and GNB results in a significantly lower occurrence of sensory or motor block affecting the tibial and common peroneal nerves compared to ACB and IPACK",[73,74],"Nerve Block","Regional Anaesthesia",[76,77,78,79],"adductor canal block","interspace between popliteal artery and capsule of knee","knee arthroplasty","genicular nerve block","NOT_YET_RECRUITING","2025-03-06",{"date":83,"type":84},"2025-03-07","ACTUAL",{"date":86,"type":67},"2025-03-15",{"date":88,"type":67},"2025-10-15",{"name":5,"class":6},1]