[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100589651":3},{"organization":4,"armGroups":7,"interventions":18,"overallOfficials":25,"centralContacts":30,"locations":24,"responsibleParty":39,"collaborators":24,"id":41,"slug":42,"hasResults":43,"nctId":44,"briefTitle":45,"officialTitle":45,"acronym":24,"eligibilityCriteria":46,"healthyVolunteers":47,"sex":48,"minAge":49,"maxAge":50,"enrollmentInfo":51,"targetDuration":24,"studyType":54,"phases":55,"briefSummary":57,"conditions":58,"keywords":24,"overallStatus":60,"whyStopped":24,"lastUpdateSubmitDate":61,"lastUpdatePostDateStruct":62,"startDateStruct":65,"completionDateStruct":67,"leadSponsor":69,"locationsCount":24},{"fullName":5,"class":6},"Ain Shams University","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"group A","ACTIVE_COMPARATOR","40 patients will have bladder dissection at the start of caesarean section for patient with morbidly adherent placenta",[13],"Procedure: bladder dissection in placenta accreta spectrum",{"label":15,"type":10,"description":16,"interventionNames":17},"group b","40 patients will have bladder dissection after closing uterine incision and just before clamping uterine artery in case of caesarean hysterectomy",[13],[19],{"type":20,"name":21,"description":22,"armGroupLabels":23,"otherNames":24},"PROCEDURE","bladder dissection in placenta accreta spectrum","All caesarean sections will be performed by a surgeon who has experience in performing caesarean hysterectomy in both groups.\n\n* Scrubbing the abdomen as usual.\n* Subumblical midline skin incision versus Pfannenstiel incision will be chosen according to site of the placenta and previous surgeries.\n* In group A careful bladder dissection will be done before uterine incision with ensuring hemostasis, uterine incision will be done above the placenta, after delivering the baby awaiting for placental separation if not proceeding for caesarean hysterectomy.\n* In group B uterine incision will be done above the placenta and after delivering the baby awaiting for placental separation if not proceeding to caesarean hysterectomy and dissecting bladder just before clamping uterine artery.",[9,15],null,[26],{"name":27,"affiliation":28,"role":29},"khaled saed, professor","direcror","STUDY_DIRECTOR",[31,36],{"name":32,"role":33,"phone":34,"phoneExt":24,"email":35},"salma M hussain, assistan lecturer","CONTACT","00201145895970","salmaa_mohd@hotmail.com",{"name":37,"role":33,"phone":38,"phoneExt":24,"email":24},"Hatem Elsayed, lecturer","00201009525878",{"type":40,"investigatorFullName":24,"investigatorTitle":24,"investigatorAffiliation":24,"oldNameTitle":24,"oldOrganization":24},"SPONSOR","100589651","a-comparison-between-bladder-dissection-before-and-after-uterine-incision-during-cesarean-section-for-placenta-accreta-spectrum-a-randomized-controlled-study-100589651",false,"NCT06957184","A Comparison Between Bladder Dissection Before and After Uterine Incision During Cesarean Section for Placenta Accreta Spectrum: A Randomized Controlled Study","Inclusion Criteria:\n\n* Women with BMI at or under 35kg\u002Fm2\n* Women with history of at least previous two caesarean section\n* Gestational age more than 32 weeks with viable fetus.\n* Women with any degree of placenta previa.\n* Women with placenta falling in the PAS.\n* Willing and able to provide informed consent.\n\nExclusion Criteria:\n\n* o History of urinary bladder injury.\n\n  * History of urinary or renal disorders\n  * Women with coagulation disorders or on anticoagulation therapy.\n  * Patients who are hemodynamically unstable before skin incision",true,"FEMALE","18 Years","45 Years",{"count":52,"type":53},80,"ESTIMATED","INTERVENTIONAL",[56],"NA","The worldwide incidence of placenta accreta spectrum is increasing, following the trend of rising caesarean delivery. It is an heterogeneous condition associated with a high maternal morbidity and mortality rate (Jauniaux et al., 2018).\n\ncaesarean hysterectomy is considered the gold standard for the treatment of placenta accreta. Also this radical approach is associated with high rates of severe maternal morbidity as hemorrhage and insult to surrounding organs during surgery (Hoffman et al., 2010).\n\nSurgeons should be able to dissect the bladder safely and confidently through minimally invasive techniques, to avoid surgical injury, it is important to use anatomic landmarks, minimize the use of cauterization (Farhat and Casale, 2018).\n\nAll centers are encouraged to develop guidelines to manage the potential urologic complications of these cases tailored to their resources (Taneja and Shah, 2017).\n\nThis study aims to evaluate the timing of bladder dissection in caesarean section in patient with placenta accreta spectrum.",[59],"Placenta Accreta","NOT_YET_RECRUITING","2025-04-26",{"date":63,"type":64},"2025-05-04","ACTUAL",{"date":66,"type":53},"2025-05-01",{"date":68,"type":53},"2026-06-15",{"name":5,"class":6}]