[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100569028":3},{"organization":4,"armGroups":7,"interventions":27,"overallOfficials":10,"centralContacts":37,"locations":47,"responsibleParty":66,"collaborators":10,"id":68,"slug":69,"hasResults":70,"nctId":71,"briefTitle":72,"officialTitle":72,"acronym":73,"eligibilityCriteria":74,"healthyVolunteers":75,"sex":76,"minAge":77,"maxAge":78,"enrollmentInfo":79,"targetDuration":10,"studyType":82,"phases":10,"briefSummary":83,"conditions":84,"keywords":86,"overallStatus":50,"whyStopped":10,"lastUpdateSubmitDate":92,"lastUpdatePostDateStruct":93,"startDateStruct":96,"completionDateStruct":98,"leadSponsor":100,"locationsCount":101},{"fullName":5,"class":6},"Swiss Paraplegic Research, Nottwil","NETWORK",[8,14,19,23],{"label":9,"type":10,"description":11,"interventionNames":12},"Individuals with SCI - Behavioral assessment",null,"15 individuals with SCI will perform a comprehensive behavioral assessment of embodiment (see \"Interventions\"). A clinical assessment of sensory-motor symptoms will also be carried out.",[13],"Behavioral: Behavioral assessment",{"label":15,"type":10,"description":16,"interventionNames":17},"Individuals with SCI - Behavioral assessment and fMRI","25 individuals with SCI will perform a comprehensive behavioral assessment of embodiment and neural correlates of embodiment will be explored by means of an fMRI procedure (see \"Interventions\"). A clinical assessment of sensory-motor symptoms will also be carried out.",[13,18],"Behavioral: Functional Magnetic Resonance Imaging (fMRI)",{"label":20,"type":10,"description":21,"interventionNames":22},"Healthy controls - Behavioral assessment","15 healthy controls will perform a comprehensive behavioral assessment of embodiment (see \"Interventions\").",[13],{"label":24,"type":10,"description":25,"interventionNames":26},"Healthy controls - Behavioral assessment and fMRI","25 individuals with SCI will perform a comprehensive behavioral assessment of embodiment and neural correlates of embodiment will be explored by means of an fMRI procedure (see \"Interventions\").",[13,18],[28,33],{"type":29,"name":30,"description":31,"armGroupLabels":32,"otherNames":10},"BEHAVIORAL","Behavioral assessment","A comprehensive behavioral assessment of embodiment and its effect on daily living, taking into account pain, interoception, emotions and anxiety, sleep quality, life satsfaction and cognition.",[20,24,9,15],{"type":29,"name":34,"description":35,"armGroupLabels":36,"otherNames":10},"Functional Magnetic Resonance Imaging (fMRI)","Neural mechanisms of embodiments will be explored with MRI sequences including structural MRI, resting-state and task-based fMRI of the head.\n\nThe task will be a modified version of the rubber hand illusion, previously used to asess embodiment. Participants will be required to lay in the MRI with their legs bended upright and a screen placed at the level of their hips, which will show a pair of legs. The participant's leg will be stroked with a paintbrush while the image on the screen will be showing the virtual legs being stroked. Participants will be required to report how strongly they perceive the virtual legs as their own, as a measure of embodiment.",[24,15],[38,43],{"name":39,"role":40,"phone":41,"phoneExt":10,"email":42},"Giuseppe A. Zito, Dr.","CONTACT","0041419395586","giuseppe.zito@paraplegie.ch",{"name":44,"role":40,"phone":45,"phoneExt":10,"email":46},"Nicola Brunello, MSc","0041419396578","nicola.brunello@paraplegie.ch",[48],{"facility":49,"status":50,"city":51,"state":52,"zip":53,"country":54,"countryCode":55,"cosmosGeoPoint":56,"geoPoint":61,"contacts":62},"Swiss Paraplegic Research","RECRUITING","Nottwil","Canton of Lucerne","6207","Switzerland","CH",{"type":57,"coordinates":58},"Point",[59,60],8.13774,47.13469,{"lat":60,"lon":59},[63,64],{"name":44,"role":40,"phone":45,"phoneExt":10,"email":46},{"name":44,"role":65,"phone":10,"phoneExt":10,"email":10},"SUB_INVESTIGATOR",{"type":67,"investigatorFullName":10,"investigatorTitle":10,"investigatorAffiliation":10,"oldNameTitle":10,"oldOrganization":10},"SPONSOR","100569028","a-comprehensive-assessment-of-altered-embodiment-in-individuals-with-spinal-cord-injury-100569028",false,"NCT06688916","A Comprehensive Assessment of Altered Embodiment in Individuals With Spinal Cord Injury","SCI_Embodiment","Inclusion Criteria for all participants:\n\n* Age between 18 and 60\n* Normal or corrected-to-normal visual acuity\n* German or Italian native speaker\n\nAdditional Inclusion Criteria only for individuals with SCI:\n\n* Diagnosis of traumatic spinal cord injury\n* Lesion level below T1 (first thoracic vertebra)\n* Time since injury \\>= 12 months\n* Residual sensation on the upper leg (sensory capability of 1 or higher on at least one leg in the dermatomes L2 and L3 for both light touch and pin prick).\n\nExclusion Criteria for all participants:\n\n* Pregnancy or breastfeeding\n* Diagnosis of other psychiatric or neurological disorders (e.g. epilepsy, tumor in the central nervous system)\n* Confirmed diagnosis of alcohol and\u002For drug abuse with active consumption within the last 6 months\n* Confirmed diagnosis of traumatic brain injury, intended as visible changes in the brain diagnosed by a radiologist\n* Stroke\n* Inability to perform study procedures (e.g. inability to consent)\n\nAdditional Exclusion Criteria for both HC and SCI undergoing the fMRI procedure:\n\n* Active medical devices (e.g. cardiac pacemaker)\n* Inability to perform study procedures (e.g. claustrophobia)",true,"ALL","18 Years","65 Years",{"count":80,"type":81},80,"ESTIMATED","OBSERVATIONAL","Spinal cord injury (SCI) occurs when trauma or other factors damage the spinal cord, disrupting the flow of sensory information from the body to the brain. This interruption can interfere with embodiment-the body awareness and physical sensations processed by the brain-sometimes leading to a phenomenon called disembodiment.\n\nFor people with SCI, disembodiment may appear as unusual body sensations, like feeling that a limb is in a different position than it actually is. Such changes in body awareness can impact daily life, mental health, and rehabilitation outcomes.\n\nDespite its importance, the study of embodiment in SCI remains limited. This project aims to explore how SCI alters embodiment, focusing on its specific characteristics, the effects on daily life, and the underlying brain activity as measured by functional magnetic resonance imaging (fMRI). Both people with and without SCI will participate.\n\nProcedure: Participants will complete a single examination lasting 2 to 2.5 hours, including approximately 55 minutes in the MRI scanner (with preparation and follow-up).",[85],"Spinal Cord Injuries (SCI)",[87,88,89,90,91],"spinal cord injury","embodiment","bodily sensations","magnetic resonance imaging","daily life","2025-10-02",{"date":94,"type":95},"2025-10-08","ACTUAL",{"date":97,"type":95},"2025-06-04",{"date":99,"type":81},"2026-05",{"name":5,"class":6},1]