[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100469759":3},{"organization":4,"armGroups":7,"interventions":18,"overallOfficials":10,"centralContacts":22,"locations":32,"responsibleParty":51,"collaborators":10,"id":55,"slug":56,"hasResults":57,"nctId":58,"briefTitle":59,"officialTitle":60,"acronym":10,"eligibilityCriteria":61,"healthyVolunteers":57,"sex":62,"minAge":63,"maxAge":64,"enrollmentInfo":65,"targetDuration":68,"studyType":69,"phases":10,"briefSummary":70,"conditions":71,"keywords":73,"overallStatus":77,"whyStopped":10,"lastUpdateSubmitDate":78,"lastUpdatePostDateStruct":79,"startDateStruct":82,"completionDateStruct":84,"leadSponsor":86,"locationsCount":87},{"fullName":5,"class":6},"Central South University","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"First-onset of depressed patients",null,"first attack",[13],"Other: No intervention",{"label":15,"type":10,"description":16,"interventionNames":17},"Patients with recurrent depression","relapse",[13],[19],{"type":6,"name":20,"description":20,"armGroupLabels":21,"otherNames":10},"No intervention",[9,15],[23,28],{"name":24,"role":25,"phone":26,"phoneExt":10,"email":27},"Renrong H Wu, M.D. Ph.D","CONTACT","+8615874149855","wurenrong@csu.edu.cn",{"name":29,"role":25,"phone":30,"phoneExt":10,"email":31},"Jing Huang, Ph.D","+8615874290980","jinghuangserena001@csu.edu.cn",[33],{"facility":34,"status":10,"city":35,"state":36,"zip":37,"country":38,"countryCode":39,"cosmosGeoPoint":40,"geoPoint":45,"contacts":46},"Mental Health Institute of 2nd Xiangya Hospital,CSU","Changsha","Hunan","410001","China","CN",{"type":41,"coordinates":42},"Point",[43,44],112.97087,28.19874,{"lat":44,"lon":43},[47,49],{"name":48,"role":25,"phone":26,"phoneExt":10,"email":27},"Renrong Wu, M.D. Ph.D",{"name":50,"role":25,"phone":30,"phoneExt":10,"email":31},"Jing Huang, M.D. Ph.D",{"type":52,"investigatorFullName":53,"investigatorTitle":54,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"PRINCIPAL_INVESTIGATOR","Renrong Wu","Professor","100469759","a-correlation-study-of-cognitive-function-in-patients-with-depression-100469759",false,"NCT05396989","A Correlation Study of Cognitive Function in Patients With Depression","Near-infrared, Eye Movement and Depressive Symptoms in Patients With Depression Correlation Study of Cognitive Function: a Prospective Observational Cohort Study","Inclusion Criteria:\n\n1. Meets the DSM-5 (Diagnostic and Statistical Manual of Mental Disorders, 5th Edition) diagnostic criteria for depressive disorders\n2. Age 18-60 years, gender aside, at least 1 guardian to monitor the patient for 2 months\n3. Obtain informed consent from patients and guardians, sign informed consent forms, and be able to comply with planned visits, laboratory tests, and other research procedures\n4. It is expected that there will be no problems such as relocation of residence, inconvenience of transportation, and difficulty in obtaining medical treatment throughout the study process\n5. There is sufficient audiovisual level to complete the necessary examinations for the study\n\nExclusion Criteria:\n\n1. Presence of any other medical disorder affecting reproductive endocrine function; Abusers of psychoactive substances or substances such as alcohol\n2. People with severe physical disabilities who are unable to complete follow-up\n3. Have been diagnosed or have had other severe psychiatric disorders that meet the diagnostic criteria for DSM-5, mental retardation, dementia, severe cognitive dysfunction, etc\n4. Previously or currently suffering from any major physical disease, neurological disorder, brain trauma, etc. that affect the structure or function of the brain\n5. Suicidal or uncooperative\n6. Pregnant or lactating women\n7. There is significant anxiety, HAMA ≥ 21 points","ALL","18 Years","60 Years",{"count":66,"type":67},200,"ESTIMATED","3 Months","OBSERVATIONAL","Many studies have shown that patients with depression had weak brain region connections and low levels of activation of the prefrontal lobe when brain activity was active and that patients with depression have a negative attentional bias, and the patient's abnormal attentional allocation may stem from a loss of attention avoidance of negative cues and a loss of attention preference for positive cues. Here use the near-infrared, eye movement to evaluate the cognitive function in patients with depression. The purpose of the study is to explore the correlation between depressed symptom and cognition function among the depression patients and the difference between first-onset of depressed patients and those is recurrent.",[72],"Depression",[72,74,75,76],"cognition function","Near-infrared","Eye movement","NOT_YET_RECRUITING","2023-06-30",{"date":80,"type":81},"2023-07-03","ACTUAL",{"date":83,"type":67},"2024-05-06",{"date":85,"type":67},"2028-05-28",{"name":5,"class":6},1]