[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100481434":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":39,"centralContacts":44,"locations":52,"responsibleParty":86,"collaborators":88,"id":97,"slug":98,"hasResults":99,"nctId":100,"briefTitle":101,"officialTitle":102,"acronym":25,"eligibilityCriteria":103,"healthyVolunteers":104,"sex":105,"minAge":106,"maxAge":25,"enrollmentInfo":107,"targetDuration":25,"studyType":110,"phases":111,"briefSummary":113,"conditions":114,"keywords":116,"overallStatus":55,"whyStopped":25,"lastUpdateSubmitDate":120,"lastUpdatePostDateStruct":121,"startDateStruct":124,"completionDateStruct":126,"leadSponsor":128,"locationsCount":129},{"fullName":5,"class":6},"Universitair Ziekenhuis Brussel","OTHER",[8,13],{"label":9,"type":6,"description":10,"interventionNames":11},"General population","In this group, younger adults (18-64) and older (from 65 and older) from the general population are included. The participants fill in questionnaires.",[12],"Other: PID-5-BF+M and LPFS-BF 2.0 (self-report questionnaires)",{"label":14,"type":6,"description":15,"interventionNames":16},"Clinical Population","In this group, in- and outpatients from the clinical population are included. This are older adults, from the age of 65 with varying psychological pathologies (such as anxiety disorders, mood disorders, substance use disorders, developmental disorders, personality pathology, grief, trauma-related disorders, psychosocial problems, psychosis and schizophrenia-related disorders and somatic disorders). The patients fill in questionnaires and a randomly selected smaller group of patients will conduct a clinical interview.",[12,17,18,19],"Other: Secondary Questionnaires (self-report and informant questionnaires)","Diagnostic Test: Clinical Ratings of the dimensional model","Other: PID-5-BF+M and LPFS-BF 2.0 (Informant questionnaires)",[21,26,30,35],{"type":6,"name":22,"description":23,"armGroupLabels":24,"otherNames":25},"PID-5-BF+M and LPFS-BF 2.0 (self-report questionnaires)","All participants will be asked to fill in the PID-5-BF+M and the LPFS-BF 2.0 to examine personality disorders as defined by the AMPD and ICD-11.\n\nPID-5-BF+M consists of 36 self-report items. It has 18 facet scales and 6 domain scales (Anankastia, Negative Affectivity, Antagonism, Disinhibition, Psychoticism and Detachment).\n\nThe LPFS-BF 2.0 has 12 items, measuring 4 domains of personality functioning (identity, intimacy, self-direction and empathy).",[14,9],null,{"type":6,"name":27,"description":28,"armGroupLabels":29,"otherNames":25},"Secondary Questionnaires (self-report and informant questionnaires)","The patients fill in a standard test battery during the first weeks of their admission in the institutions, including questionnaires and interviews. The research team will analyze the results retrospectively.\n\nThis includes:\n\nYSQ- SF16 (Young \\& Brown, 1994; Pauwels et al., 2018) GPS (van Alphen et al., 2006) HoNOS 65+ (Burns et al., 1999) HAP 2.0 (Barendse \\& Thissen, 2006) SCL-90-R (Derogatis, 1983; Dutch version: Arrindell, \\& Ettema, 1975, 1986, 2005) ADP-IV (Schotte \\& De Doncker, 1998) CERQ (Garnefski et al., 2007) UCL (Scheurs et al., 1994; 1988) BIS\u002FBAS Scales (Carver \\& White, 1994) EC Scale of the ATQ (Rothbart et al., 2000) BSI (Derogatis, 1975; Dutch version: Beurs, 2008) SIPP-SF (derived from the SIPP-118; Verheul et al., 2008) SMI (Young et al., 2008) WHO-5 (Dutch version: WHO, 1998) SQ3-SF (Young \\& Brown, 2005) SCID-5-P (First et al., 2017; Dutch translation: Arntz et al., 2017)",[14],{"type":31,"name":32,"description":33,"armGroupLabels":34,"otherNames":25},"DIAGNOSTIC_TEST","Clinical Ratings of the dimensional model","Clinical ratings of criteria A and B will also be collected. Only a small part of the patients will be selected for this, in order to make the research more feasible. The rater (a clinician or researcher) assesses the patient (in terms of level of personality functioning and personality traits) by means of (structured) clinical interviews. Given clinical ratings of the dimensional criteria are not part of the standard care in either institution, the ratings can be conducted by the doctorandus and Master Thesis students, trained by the doctorandus (in order not to overburden the clinicians).\n\nThe clinical interviews that will be used for the ratings are:\n\n* The Semigestructureerd Interview voor Persoonlijkheidsfunctioneren DSM-5 (STIP) (Hutsebaut et al., 2014).\n* The Structured Clinical Interview for the DSM-5 (SCID-5-AMPD) (First et al., 2018), only if a Dutch translation is available by the time of this intervention.",[14],{"type":6,"name":36,"description":37,"armGroupLabels":38,"otherNames":25},"PID-5-BF+M and LPFS-BF 2.0 (Informant questionnaires)","In the clinical population, participants will be asked to include an informant (family member, partner, friend, acquaintance), to fill in an informant version of the PID-5-BF+M and LPFS-BF 2.0 questionnaires. It is also possible for the patient to participate in the study without giving permission to include an informant. The informant will be asked to fill in the informant versions of the questionnaires, which contain the exact same items as the self-report versions, adjusted to the third person.",[14],[40],{"name":41,"affiliation":42,"role":43},"Morag Facon","Vrije Universiteit Brussel","PRINCIPAL_INVESTIGATOR",[45,49],{"name":41,"role":46,"phone":47,"phoneExt":25,"email":48},"CONTACT","+32493596294","morag.flora.facon@vub.be",{"name":50,"role":46,"phone":25,"phoneExt":25,"email":51},"Gina Rossi","gina.rossi@vub.be",[53,70],{"facility":54,"status":55,"city":56,"state":57,"zip":58,"country":59,"countryCode":60,"cosmosGeoPoint":61,"geoPoint":66,"contacts":67},"Alexianen Zorggroep Tienen","RECRUITING","Tienen","Vlaams-Brabant","3300","Belgium","BE",{"type":62,"coordinates":63},"Point",[64,65],4.9378,50.80745,{"lat":65,"lon":64},[68],{"name":69,"role":46,"phone":25,"phoneExt":25,"email":25},"Eva Dierckx",{"facility":71,"status":72,"city":73,"state":74,"zip":75,"country":76,"countryCode":77,"cosmosGeoPoint":78,"geoPoint":82,"contacts":83},"Mondriaan","NOT_YET_RECRUITING","Heerlen","Limburg","6411 - 6422","Netherlands","NL",{"type":62,"coordinates":79},[80,81],5.98154,50.88365,{"lat":81,"lon":80},[84],{"name":85,"role":46,"phone":25,"phoneExt":25,"email":25},"Bas van Alphen",{"type":87,"investigatorFullName":25,"investigatorTitle":25,"investigatorAffiliation":25,"oldNameTitle":25,"oldOrganization":25},"SPONSOR",[89,91,93,95],{"name":90,"class":6},"Fund for Scientific Research, Flanders, Belgium",{"name":54,"class":92},"UNKNOWN",{"name":71,"class":94},"AMBIG",{"name":96,"class":6},"GGZ Breburg","100481434","a-dimensional-model-for-personality-disorders-in-later-life-100481434",false,"NCT05548946","A Dimensional Model for Personality Disorders in Later Life","Empirical Evaluation and Clinical Relevance of a Dimensional Model for Personality Disorders in Later Life","Clinical population (inpatients and outpatients)\n\nInclusion Criteria:\n\n* ONLY older adults: from the age of 65\n* Dutch speaking\n\nExclusion Criteria (as evaluated by the psychiatrists and psychologists of the participating institutions):\n\n* Severe cognitive impairment (Patients who are admitted because of cognitive impairment will be excluded from the participant pool, other than this the psychiatrists and psychologists of the participating institutions will make an evaluation of the patients' cognitive capacities)\n* Acute state of mental impairment which would interfere with the reliability of the patients' responses (for example severe psychosis), as evaluated by the psychiatrists and psychologist of the participating institutions.",true,"ALL","18 Years",{"count":108,"type":109},750,"ESTIMATED","INTERVENTIONAL",[112],"NA","Research on personality disorders (PDs) in older adults is currently limited. This is surprising, given that PDs are also common in this age group. Moreover, PDs show high co-morbidity with other disorders (both mental and physical) and often have a negative effect on treatment. With this in mind, the conceptualization, diagnosis and treatment of PDs in older adults represents an important task for mental health care. To this end, problems with the current classification of PDs need to be tackled, as they currently complicate this task. The current DSM-5 (Diagnostic and Statistical Manual, Edition 5) (APA, 2013) categorical PD criteria are mainly based on the living conditions of younger adults and are therefore often not suited for PD diagnosis in older adults. Currently, however, a paradigm shift is taking place from a categorical to a dimensional approach of PDs. The \"Alternative Model for Personality Disorders\" (AMPD) (APA, 2013) and the approach by ICD-11 (International Classification of Diseases 11th Revision) (WHO, 2019) are examples of new, dimensional models for PDs. These models conceptualize PDs using two dimensional criteria: (1) criterion A, which captures the overall level of personality (dis)functioning and (2) criterion B which describes the PD style by pathological\u002Fmaladaptive personality traits. This paradigm shift offers the possibility to give the aging context the attention it deserves, by examining the suitability of this new dimensional conceptualization of PD among older adults.\n\nThe goal of this research is to examine whether the combined AMPD and ICD-11 dimensional approach is appropriate for use in older adults. This will be done by administering instruments capturing criterion A and B in the general population in younger (18-64) and older (65 and older) adults to evaluate their age-neutrality, as well as in a clinical sample of older (65 and older) adults, to empirically evaluate its clinical relevance in later life.",[115],"Psychiatric Disorders",[117,118,119],"Personality Psychology","Aging","Psychological Assessment","2024-12-04",{"date":122,"type":123},"2024-12-09","ACTUAL",{"date":125,"type":123},"2022-09-01",{"date":127,"type":109},"2025-11",{"name":5,"class":6},2]