[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100519224":3},{"organization":4,"armGroups":7,"interventions":25,"overallOfficials":62,"centralContacts":67,"locations":73,"responsibleParty":90,"collaborators":92,"id":95,"slug":96,"hasResults":97,"nctId":98,"briefTitle":99,"officialTitle":100,"acronym":37,"eligibilityCriteria":101,"healthyVolunteers":97,"sex":102,"minAge":103,"maxAge":37,"enrollmentInfo":104,"targetDuration":37,"studyType":107,"phases":108,"briefSummary":110,"conditions":111,"keywords":37,"overallStatus":75,"whyStopped":37,"lastUpdateSubmitDate":116,"lastUpdatePostDateStruct":117,"startDateStruct":120,"completionDateStruct":122,"leadSponsor":124,"locationsCount":125},{"fullName":5,"class":6},"University of Washington","OTHER",[8,19],{"label":9,"type":10,"description":11,"interventionNames":12},"Arm A ([P]REHAB intervention)","EXPERIMENTAL","Starting at least 4 weeks prior to date of surgery, patients use the ExerciseRx app to follow the (P)REHAB exercise program, which consists of four 20-30 minute home exercise sessions per week and personalized step count goal setting and tracking, while receiving SOC chemotherapy, if applicable, prior to SOC surgery and for 90 days following surgery (total \\~4-7 months). Patients also download the FitBit app and wear a FitBit throughout the study.",[13,14,15,16,17,18],"Other: Exercise Intervention","Other: App-Based Intervention","Other: Interview","Other: Wearable Activity Tracker","Other: Physical Performance Testing","Other: Questionnaire Administration",{"label":20,"type":21,"description":22,"interventionNames":23},"Arm B (standard of care)","ACTIVE_COMPARATOR","Patients receive SOC educational materials and, starting at least 4 weeks prior to date of surgery, patients wear a FitBit and use the FitBit app while receiving SOC chemotherapy, if applicable, prior to SOC surgery.",[24,14,16,17,18],"Other: Best Practice",[26,33,38,42,45,49,53,59],{"type":6,"name":27,"description":28,"armGroupLabels":29,"otherNames":30},"Best Practice","Receive SOC educational materials",[20],[31,32],"standard of care","standard therapy",{"type":6,"name":34,"description":35,"armGroupLabels":36,"otherNames":37},"Exercise Intervention","Receive (P)REHAB exercise program",[9],null,{"type":6,"name":39,"description":40,"armGroupLabels":41,"otherNames":37},"App-Based Intervention","Use ExerciseRx app",[9],{"type":6,"name":39,"description":43,"armGroupLabels":44,"otherNames":37},"Use FitBit app",[9,20],{"type":6,"name":46,"description":47,"armGroupLabels":48,"otherNames":37},"Interview","Ancillary studies",[9],{"type":6,"name":50,"description":51,"armGroupLabels":52,"otherNames":37},"Wearable Activity Tracker","Wear FitBit",[9,20],{"type":6,"name":54,"description":47,"armGroupLabels":55,"otherNames":56},"Physical Performance Testing",[9,20],[57,58],"Physical Fitness Testing","Physical Function Testing",{"type":6,"name":60,"description":47,"armGroupLabels":61,"otherNames":37},"Questionnaire Administration",[9,20],[63],{"name":64,"affiliation":65,"role":66},"Sarah Psutka","Fred Hutch\u002FUniversity of Washington Cancer Consortium","PRINCIPAL_INVESTIGATOR",[68],{"name":69,"role":70,"phone":71,"phoneExt":37,"email":72},"Get Moving Research Coordinator","CONTACT","206-210-4040","GetMoving@uw.edu",[74],{"facility":65,"status":75,"city":76,"state":77,"zip":78,"country":79,"countryCode":80,"cosmosGeoPoint":81,"geoPoint":86,"contacts":87},"RECRUITING","Seattle","Washington","98109","United States","US",{"type":82,"coordinates":83},"Point",[84,85],-122.33207,47.60621,{"lat":85,"lon":84},[88,89],{"name":69,"role":70,"phone":71,"phoneExt":37,"email":72},{"name":64,"role":66,"phone":37,"phoneExt":37,"email":37},{"type":91,"investigatorFullName":37,"investigatorTitle":37,"investigatorAffiliation":37,"oldNameTitle":37,"oldOrganization":37},"SPONSOR",[93],{"name":94,"class":6},"Bladder Cancer Advocacy Network","100519224","a-home-based-prehabilitation-exercise-intervention-for-improving-physical-function-in-patients-with-bladder-cancer-and-upper-tract-urothelial-cancer-get-moving-trial-100519224",false,"NCT06040762","A Home-Based Prehabilitation Exercise Intervention for Improving Physical Function in Patients With Bladder Cancer and Upper Tract Urothelial Cancer, Get Moving Trial","The \"Get Moving Trial\": A Phase I\u002FII RCT of Home-Based (P)Rehabilitation With ExerciseRx in Bladder Cancer and Upper Tract Urothelial Cancer","Inclusion Criteria:\n\n* 18 years of age or older\n* English-speaking\n* Planned treatment with radical cystectomy or radical nephroureterectomy\u002Fureterectomy with or without preceding systemic therapy as indicated by the patient's surgeon with enough time to complete a minimum of 4 weeks of exercises before surgery if enrolled in the (P)REHAB arm\n* Willing and able to participate in trial activities\n\nExclusion Criteria:\n\n* Cognitive\u002Fmental impairment that will preclude ability to participate in routine exercise activities. Significant cognitive or memory impairment or baseline dementia that would preclude a patient's ability to follow instructions or reproduce exercises\n* Immobility, inability\u002Funwillingness to perform personalized exercise program. Inability to perform exercises safely from seated or standing position at home or recent falls or high fall risk. Neurologic or orthopedic condition(s) that restricts participation in unsupervised home exercises, such as prior stroke with neurologic impairment, weight-bearing precautions, or unwillingness to participate in exercises\n* Participants who have nonmuscle-invasive urothelial cancer of the bladder\u002Fupper tract anticipating undergoing organ-preserving treatments, or radiographic evidence of metastatic disease involving other organs including brain metastases.\n* Patients with predominant histology other than urothelial carcinoma of the bladder or upper tracts (e.g. metastasis from another cancer) who would not otherwise be considered candidates for standard definitive or consolidative surgeries (radical cystectomy, ureterectomy, radical nephroureterectomy) with\u002Fwithout treatment with preoperative\u002Fneoadjuvant systemic therapy.\n* Uncontrolled or concurrent illness including, but not limited to, ongoing or active infection, symptomatic congestive heart failure, unstable angina pectoris, cardiac arrhythmia, or psychiatric illness\u002Fsocial situations that would limit compliance with study requirements\n* Pregnant women are excluded from this study\n* Inability to understand or read English\n* Lack of access or lack of sufficient facility to use an Android or iOS smart device with the minimum criteria for using ExerciseRx\n* Not receiving surgery at UWMC\n* Participation in a clinical trial that does not permit enrollment in the Get Moving trial","ALL","18 Years",{"count":105,"type":106},128,"ESTIMATED","INTERVENTIONAL",[109],"NA","Prehabilitation refers to the process of improving a patient's functional capabilities prior to a surgical procedure with the goal of decreasing post-surgical inactivity and physical decline. This clinical trial evaluates the utility of a personalized home-based prehabilitation exercise intervention for the improvement of physical function and surgical outcomes in patients with urothelial carcinoma undergoing definitive or consolidative surgery of the bladder (radical cystectomy) or upper tract (nephroureterectomy, ureterectomy) with or without preceding neoadjuvant\u002Fsystemic therapy. The exercise intervention includes at-home exercise sessions focused on the improvement of core strength and balance as well as personalized step count goals, delivered to patients remotely via a smart-device-based application (ExerciseRx). Encouraging physical activity before surgery may improve physical function and surgical outcomes in patients who are scheduled to undergo surgery for their bladder or urothelial cancer.",[112,113,114,115],"Bladder Cancer","Urothelial Carcinoma","Upper Tract Urothelial Carcinoma","Renal Pelvis and Ureter Urothelial Carcinoma","2026-02-26",{"date":118,"type":119},"2026-03-02","ACTUAL",{"date":121,"type":119},"2023-12-19",{"date":123,"type":106},"2027-04-30",{"name":5,"class":6},1]