[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100627098":3},{"organization":4,"armGroups":7,"interventions":10,"overallOfficials":18,"centralContacts":22,"locations":27,"responsibleParty":44,"collaborators":46,"id":50,"slug":51,"hasResults":52,"nctId":53,"briefTitle":54,"officialTitle":55,"acronym":10,"eligibilityCriteria":56,"healthyVolunteers":52,"sex":57,"minAge":58,"maxAge":10,"enrollmentInfo":59,"targetDuration":10,"studyType":62,"phases":10,"briefSummary":63,"conditions":64,"keywords":66,"overallStatus":29,"whyStopped":10,"lastUpdateSubmitDate":73,"lastUpdatePostDateStruct":74,"startDateStruct":77,"completionDateStruct":79,"leadSponsor":81,"locationsCount":82},{"fullName":5,"class":6},"St. Jude Children's Research Hospital","OTHER",[8,12,15],{"label":9,"type":10,"description":11,"interventionNames":10},"Patient participants",null,"Patient participants 12 to 25 years of age, with a primary cancer diagnosis that is relapsed, refractory, or without curative standard-of-care options and be enrolled OR planning to enroll in a phase 1 or phase 2 trial for cancer-directed therapy.",{"label":13,"type":10,"description":14,"interventionNames":10},"Caregiver participants","Parent or primary caregiver to a child of any age who has a primary cancer diagnosis that is relapsed, refractory, or without curative standard-of-care options, is enrolled OR planning to enroll on a phase 1 or phase 2 trial for cancer-directed therapy and is ≥ 18 years of age or legally emancipated.",{"label":16,"type":10,"description":17,"interventionNames":10},"Healthcare Clinician participants","A physician, advanced practice provider, or nurse providing direct patient care to the patient participant and\u002For to the child of the caregiver participant.\n\nA psychosocial clinician (e.g., social worker, psychologist, chaplain, child life specialist, music therapist, cultural navigator, etc.) who provides direct or consultative care to pediatric or adolescent\u002Fyoung adult patients with relapsed, refractory, or high-risk cancer and\u002For their families.",[19],{"name":20,"affiliation":5,"role":21},"Alexandra Superdock, MD","PRINCIPAL_INVESTIGATOR",[23],{"name":20,"role":24,"phone":25,"phoneExt":10,"email":26},"CONTACT","888-226-4343","referralinfo@stjude.org",[28],{"facility":5,"status":29,"city":30,"state":31,"zip":32,"country":33,"countryCode":34,"cosmosGeoPoint":35,"geoPoint":40,"contacts":41},"RECRUITING","Memphis","Tennessee","38105","United States","US",{"type":36,"coordinates":37},"Point",[38,39],-90.04898,35.14953,{"lat":39,"lon":38},[42,43],{"name":20,"role":24,"phone":25,"phoneExt":10,"email":26},{"name":20,"role":21,"phone":10,"phoneExt":10,"email":10},{"type":45,"investigatorFullName":10,"investigatorTitle":10,"investigatorAffiliation":10,"oldNameTitle":10,"oldOrganization":10},"SPONSOR",[47],{"name":48,"class":49},"National Cancer Institute (NCI)","NIH","100627098","a-longitudinal-photo-narrative-exploration-of-hope-during-phase-12-clinical-trials-for-pediatric-cancer-100627098",false,"NCT07444216","A Longitudinal Photo-Narrative Exploration of Hope During Phase 1\u002F2 Clinical Trials For Pediatric Cancer","Sharing Hope: A Longitudinal Photo-Narrative Exploration of Hope During Phase 1\u002F2 Clinical Trials For Pediatric Cancer","Inclusion Criteria:\n\nPatient participants must\n\n* Be 12 to 25 years of age.\n\nAND\n\n* Have a primary cancer diagnosis that is relapsed, refractory, or without curative standard-of-care options as follows:\n\n  * 'Relapsed' disease is defined as disease recurrence following a prior complete or partial response to initial therapy.\n  * 'Refractory' disease is defined as failure to achieve remission or response with standard upfront therapy.\n  * Diagnoses will be considered 'without curative standard of care options' if there is no evidence-based curative treatment regimen or where standard therapies offer only palliative or non-curative intent (based on the assessment of the primary attending or division tumor board).\n\nAND\n\n* Be enrolled OR planning to enroll in a phase 1 or phase 2 trial for cancer-directed therapy.\\* Patients will remain eligible until 4 weeks after they begin trial therapy, after which they are no longer eligible unless they subsequently enroll on a different clinical trial.\n\nCaregiver participants must\n\n* Be a parent or primary caregiver to a child of any age who\n\n  * Has a primary cancer diagnosis that is relapsed, refractory, or without curative standard-of-care options\n\nAND\n\n* Is enrolled OR planning to enroll on a phase 1 or phase 2 trial for cancer-directed therapy.\\* Parents will remain eligible until 4 weeks after their child begins trial therapy, after which they are no longer eligible unless their child subsequently enrolls on a different clinical trial.\n\n  * Be ≥ 18 years of age or legally emancipated\n\nMedical clinician participants (Primary Objectives 1-2) must\n\n* Be a physician, advanced practice provider, or nurse providing direct patient care to the patient participant and\u002For to the child of the caregiver participant.\n\nPsychosocial clinician participants (Primary Objective 2 only) must\n\n* Be a psychosocial clinician (e.g., social worker, psychologist, chaplain, child life specialist, music therapist, cultural navigator, etc.)\n\nAND\n\n* Provide direct or consultative care to pediatric or adolescent\u002Fyoung adult patients with relapsed, refractory, or high-risk cancer and\u002For their families.\n\nExclusion Criteria:\n\nPatients, Caregivers, and Clinicians will be excluded if they:\n\n* Do not meet inclusion criteria.\n* Decline, refuse, or are unwilling to participate.\n* Are a minor without a legal guardian available or willing to provide informed consent.\n* Lack the cognitive, communicative, or physical capacity to meaningfully participate in a photo-narrative interview, as determined by the research team in consultation with the patient, caregiver, and primary oncology team. This includes, but is not limited to, individuals with profound neurocognitive impairment, non-responsiveness, or other conditions that preclude the ability to engage in basic reflection, expression, or shared conversation about images.","ALL","12 Years",{"count":60,"type":61},100,"ESTIMATED","OBSERVATIONAL","The purpose of this study is to find better ways to help support families in their hopes during cancer treatment.\n\nPrimary Objective\n\n* To characterize themes related to how patients and parents\u002Fcaregivers narrate their experience of 'hope' when receiving cancer therapy on a phase 1\u002F2 clinical trial, with a focus on whether, why, when, and how patients' and caregivers' hopes adapt to changing circumstances.\n* To engage patients, caregivers, and clinicians in focus groups to identify strengths, weaknesses, opportunities, and threats to hope during phase 1\u002F2 clinical trial participation and facilitate the co-design of a stakeholder-driven supportive intervention related to hope based on focus group recommendations.\n\nSecondary Objective\n\n* To describe health care provider perspectives on patient and family hope and goal-care concordance in the context of phase 1\u002F2 clinical trials.",[65],"Cancer, Therapy-Related",[67,68,69,70,71,72],"Photo-elicitation","Patient Participants","Parents\u002FCaregivers","Clinicians","Interviews","Focus Groups","2026-04-24",{"date":75,"type":76},"2026-04-28","ACTUAL",{"date":78,"type":76},"2026-04-09",{"date":80,"type":61},"2030-03",{"name":5,"class":6},1]