[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100570513":3},{"organization":4,"armGroups":7,"interventions":13,"overallOfficials":20,"centralContacts":24,"locations":30,"responsibleParty":51,"collaborators":53,"id":56,"slug":57,"hasResults":58,"nctId":59,"briefTitle":60,"officialTitle":61,"acronym":9,"eligibilityCriteria":62,"healthyVolunteers":58,"sex":63,"minAge":64,"maxAge":19,"enrollmentInfo":65,"targetDuration":19,"studyType":68,"phases":69,"briefSummary":71,"conditions":72,"keywords":74,"overallStatus":82,"whyStopped":19,"lastUpdateSubmitDate":83,"lastUpdatePostDateStruct":84,"startDateStruct":87,"completionDateStruct":89,"leadSponsor":91,"locationsCount":92},{"fullName":5,"class":6},"University of Sydney","OTHER",[8],{"label":9,"type":10,"description":9,"interventionNames":11},"Real-Time IGRT","EXPERIMENTAL",[12],"Device: Real-Time Image Guided Radio Therapy (IGRT)",[14],{"type":15,"name":16,"description":17,"armGroupLabels":18,"otherNames":19},"DEVICE","Real-Time Image Guided Radio Therapy (IGRT)","Real-time image guided radiation therapy (IGRT) methods image the cancerous tumour in real-time, enabling the treatment beam to focus its destructive energy on the patient's cancer, not their healthy tissue.",[9],null,[21],{"name":22,"affiliation":5,"role":23},"Paul Keall","PRINCIPAL_INVESTIGATOR",[25],{"name":26,"role":27,"phone":28,"phoneExt":19,"email":29},"Shona Silvester","CONTACT","+61 2 86271185","shona.silvester@sydney.edu.au",[31],{"facility":32,"status":19,"city":33,"state":34,"zip":35,"country":36,"countryCode":37,"cosmosGeoPoint":38,"geoPoint":43,"contacts":44},"Peter MacCallum Cancer Centre","Melbourne","Victoria","3000","Australia","AU",{"type":39,"coordinates":40},"Point",[41,42],144.96332,-37.814,{"lat":42,"lon":41},[45,49],{"name":46,"role":27,"phone":47,"phoneExt":19,"email":48},"Nick Hardcastle","+61 (03) 8559 6940","nick.hardcastle@petermac.org",{"name":50,"role":23,"phone":19,"phoneExt":19,"email":19},"Shankar Siva",{"type":52,"investigatorFullName":19,"investigatorTitle":19,"investigatorAffiliation":19,"oldNameTitle":19,"oldOrganization":19},"SPONSOR",[54],{"name":55,"class":6},"Medical Research Future Fund","100570513","a-master-trial-assessing-the-technical-feasibility-of-first-in-human-real-time-image-guided-radiation-therapy-methods-100570513",false,"NCT06708221","A Master Trial Assessing the Technical Feasibility of First-In-Human Real-Time Image Guided Radiation Therapy Methods","Real-Time IGRT: A Master Trial Assessing the Technical Feasibility of First-In-Human Real-Time Image Guided Radiation Therapy Methods","Inclusion Criteria:\n\n* Patients 18 years or older to be treated with curative radiation therapy\n* Patients with brain, breast, head and neck, kidney, liver, lung, pancreas, prostate or spine cancer\n* ECOG performance status 0-2\n* Ability to understand and the willingness to sign a written informed consent document\n\nExclusion Criteria:\n\n* Pregnancy,\n* Patients with any other clinically significant medical condition which, in the opinion of the treating physician, makes it undesirable for the patient to participate in the study or which could jeopardize compliance with study requirements or severe psychiatric illness\u002Fsocial situation\n* Additional inclusion and exclusion criteria may apply to a specific sub-study","ALL","18 Years",{"count":66,"type":67},40,"ESTIMATED","INTERVENTIONAL",[70],"NA","The goal of this clinical trial is to determine whether Real-Time Image Guided Radiation Therapy is a feasible method for radiation therapy delivery for patients with cancer.\n\nThe main questions it aims to answer are:\n\n* Can all fractions per patient which are intended to be delivered with the real-time IGRT method be completed as planned?\n* Can the beam accurately hit the tumour in ≥85% of fractions?\n* Are there any unexpected grade \\>3 acute toxicities?\n\nParticipants will not require any additional treatments or preparation procedures above those required for normal radiation therapy treatment, to participate in this study.",[73],"Cancer",[75,76,77,78,79,80,81,36],"cancer","IGRT","radiotherapy","radiation therapy","Image Guided Radiation Therapy","breast cancer","lung cancer","NOT_YET_RECRUITING","2026-05-18",{"date":85,"type":86},"2026-05-20","ACTUAL",{"date":88,"type":67},"2027-06",{"date":90,"type":67},"2030-12",{"name":5,"class":6},1]