[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100502208":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":34,"centralContacts":35,"locations":41,"responsibleParty":60,"collaborators":64,"id":72,"slug":73,"hasResults":74,"nctId":75,"briefTitle":76,"officialTitle":76,"acronym":34,"eligibilityCriteria":77,"healthyVolunteers":74,"sex":78,"minAge":79,"maxAge":80,"enrollmentInfo":81,"targetDuration":34,"studyType":84,"phases":85,"briefSummary":87,"conditions":88,"keywords":34,"overallStatus":43,"whyStopped":34,"lastUpdateSubmitDate":91,"lastUpdatePostDateStruct":92,"startDateStruct":95,"completionDateStruct":97,"leadSponsor":99,"locationsCount":100},{"fullName":5,"class":6},"University of Alabama at Birmingham","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"ReACT Intervention","EXPERIMENTAL","During the initial visit participant will be randomized to either Retraining and Control Therapy (ReACT) or Competent Adulthood Transition with Cognitive Behavioral, Humanistic, and Interpersonal Training (CATCH-IT) intervention.\n\nReACT includes 12 sessions with a therapist that will discuss a plan for managing FS.\n\nParticipants will have 12 therapy sessions. The first session will be in-person which will last 2 hours and the subsequent 11 sessions will be conducted via video telehealth and each session will last 1 hour.",[13],"Behavioral: ReACT",{"label":15,"type":16,"description":17,"interventionNames":18},"CATCH-IT Intervention","ACTIVE_COMPARATOR","During the initial visit participant will be randomized to either Retraining and Control Therapy (ReACT) or Competent Adulthood Transition with Cognitive Behavioral, Humanistic, and Interpersonal Training (CATCH-IT) intervention.\n\nCATCH-IT involves the parent and child completing CBT modules on the web-based CATCH-IT platform, and they will meet with a CATCH-IT coach 12 times to discuss the modules and plan how to apply this to their life and their FS.\n\nParticipants will have 12 therapy sessions. The first session will be in-person which will last 2 hours and the subsequent 11 sessions will be conducted via video telehealth and each session will last 1 hour.",[19],"Behavioral: CATCH-IT",[21,28],{"type":22,"name":23,"description":24,"armGroupLabels":25,"otherNames":26},"BEHAVIORAL","ReACT","ReACT includes 12 sessions with a therapist that will discuss a plan for managing FS.",[9],[27],"Retraining and Control Therapy",{"type":22,"name":29,"description":30,"armGroupLabels":31,"otherNames":32},"CATCH-IT","CATCH-IT involves the parent and child completing CBT modules on the web-based CATCH-IT platform, and they will meet with a CATCH-IT coach 12 times to discuss the modules and plan how to apply this to their life and their FS.",[15],[33],"Competent Adulthood Transition with Cognitive Behavioral, Humanistic, and Interpersonal Training",null,[36],{"name":37,"role":38,"phone":39,"phoneExt":34,"email":40},"Aaron Fobian, PhD","CONTACT","205-934-2241","afobian@uabmc.edu",[42],{"facility":5,"status":43,"city":44,"state":45,"zip":46,"country":47,"countryCode":48,"cosmosGeoPoint":49,"geoPoint":54,"contacts":55},"RECRUITING","Birmingham","Alabama","35294","United States","US",{"type":50,"coordinates":51},"Point",[52,53],-86.80249,33.52066,{"lat":53,"lon":52},[56],{"name":57,"role":38,"phone":58,"phoneExt":34,"email":59},"Badhma Valaiyapathi, MBBS, MPH","205-975-4205","drbadhma@uab.edu",{"type":61,"investigatorFullName":62,"investigatorTitle":63,"investigatorAffiliation":5,"oldNameTitle":34,"oldOrganization":34},"PRINCIPAL_INVESTIGATOR","Aaron Fobian","Associate Professor",[65,67,69],{"name":66,"class":6},"Yale University",{"name":68,"class":6},"Baylor College of Medicine",{"name":70,"class":71},"National Center for Complementary and Integrative Health (NCCIH)","NIH","100502208","a-multi-site-feasibility-clinical-trial-of-retraining-and-control-therapy-react-a-mind-and-body-treatment-for-pediatric-functional-seizures-100502208",false,"NCT05819268","A Multi-site Feasibility Clinical Trial of Retraining and Control Therapy (ReACT), a Mind and Body Treatment for Pediatric Functional Seizures","Inclusion Criteria:\n\n* Males and females ages 11-18\n* Diagnosis of functional seizures\n* Internet access for telehealth sessions and CATCH-IT\n\nExclusion Criteria:\n\n* Comorbid epilepsy\n* Less than 4 functional seizures per month\n* Other paroxysmal nonepileptic events (e.g. hypoxic-ischemic phenomena, sleep disorders or migraine-associated disorders)\n* Participation in other therapy\n* Severe intellectual disability\n* Severe mental illness (active delusions\u002Fhallucinations)","ALL","11 Years","18 Years",{"count":82,"type":83},108,"ESTIMATED","INTERVENTIONAL",[86],"NA","The purpose of this study is to assess the feasibility of conducting a future fully powered multi-site efficacy Randomized Controlled Trial (RCT) comparing two treatments for pediatric functional seizures (FS). In this study, 11-18-year-olds diagnosed with FS will be randomized to 12 sessions of Retraining and Control Therapy (ReACT) or Competent Adulthood Transition with Cognitive Behavioral, Humanistic, and Interpersonal Training (CATCH-IT) at 3 sites: University of Alabama at Birmingham, Yale School of Medicine\u002FYale New Haven Children's Hospital and Baylor College of Medicine\u002FTexas Children's Hospital.\n\nFeasibility of recruitment will be measured by the percentage of planned participant enrollment target obtained at each site and overall during the 18 months of planned enrollment. Acceptability will be assessed using the Acceptability Questionnaire. Participant retention will be measured by the percent of enrolled participants that complete the 2-month follow-up visit at each site and overall. For treatment fidelity assessment, 20% of each therapist's sessions will be randomly chosen and assessed for fidelity. Patient adherence will be measured in two ways: 1) the percent of ReACT or CATCH-IT sessions completed at each site and overall and 2) for ReACT, the percent of times participants report using the treatment plan during FS episodes (measured by FS diary) and for CATCH-IT, the number of times parents and children spend using CATCH-IT each week (measured by the CATCH-IT platform). These data will be used to support a future fully-powered multi-site RCT assessing the efficacy of ReACT for pediatric FS.",[89,90],"Functional Seizures","Convulsion, Non-Epileptic","2026-03-16",{"date":93,"type":94},"2026-03-17","ACTUAL",{"date":96,"type":94},"2024-03-18",{"date":98,"type":83},"2027-08",{"name":5,"class":6},1]