[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100552212":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":25,"centralContacts":30,"locations":40,"responsibleParty":57,"collaborators":25,"id":59,"slug":60,"hasResults":61,"nctId":62,"briefTitle":63,"officialTitle":64,"acronym":65,"eligibilityCriteria":66,"healthyVolunteers":61,"sex":67,"minAge":68,"maxAge":25,"enrollmentInfo":69,"targetDuration":25,"studyType":72,"phases":73,"briefSummary":75,"conditions":76,"keywords":25,"overallStatus":81,"whyStopped":25,"lastUpdateSubmitDate":82,"lastUpdatePostDateStruct":83,"startDateStruct":86,"completionDateStruct":88,"leadSponsor":90,"locationsCount":91},{"fullName":5,"class":6},"Xuanwu Hospital, Beijing","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Patients with ASD undergoing correction surgery in reference to our novel criteria","EXPERIMENTAL","Correcting deformity according to the PI-dependent clustering of sagittal spinal alignment.",[13],"Procedure: Correction strategy in reference to our PI-dependent clustering of sagittal alignment",{"label":15,"type":6,"description":16,"interventionNames":17},"Patients with ASD undergoing correction surgery in reference to SAAS score.","Correcting deformity according to the SAAS score.",[18],"Procedure: Correction strategy in reference to the SAAS score",[20,26],{"type":21,"name":22,"description":23,"armGroupLabels":24,"otherNames":25},"PROCEDURE","Correction strategy in reference to our PI-dependent clustering of sagittal alignment","For type I patients (PI \\\u003C 39.56°), the target LL = -0.13\\*PI2+9.36\\*PI-134.08; for type II patients (39.56° ≤ PI \\\u003C 49.16°), the target LL = 0.45\\*PI+26.57; for type III patients (49.16° ≤ PI \\\u003C 58.31°), the target LL = -0.15\\*PI2+17.09\\*PI-420.57; for type IV patients (PI \\> 58.31°), the target LL = 0.06\\*PI2-7.55\\*PI+289.77. Prediction intervals of 95% confidence is adopted as the target LL range.",[9],null,{"type":21,"name":27,"description":28,"armGroupLabels":29,"otherNames":25},"Correction strategy in reference to the SAAS score","This new score is composed of three sagittal parameters (PI-LL, PT and TPA). For these three parameters, points were assigned based on offset with age-adjusted targets 0 points if the parameter was within 10 years of the patient's age (Match). For each 20 years above the age-adjusted target, 1 point was added (e.g., + 1 point between + 10 and + 30, + 2 points between +30 and +50). Conversely, 1 point was subtracted for each 20 years below the age-adjusted target (e.g., -1 point between -10 and -30, -2 points between -30 and -50). SAAS was calculated by adding all 3 components, creating a discreet score that could have a negative value (under corrected) or positive value (over corrected). SAAS was sub-categorized into \"SAAS-Under\" if it was less than -1, \"SAAS-Match\" if it was between -1 and + 1 or \"SAAS-Over\" if it was greater than + 1.",[15],[31,36],{"name":32,"role":33,"phone":34,"phoneExt":25,"email":35},"Shibao Lu, M.D.","CONTACT","18810728213","wdfdoctor@126.com",{"name":37,"role":33,"phone":38,"phoneExt":25,"email":39},"Dongfan Wang, M.D.","13821337116","1026607981@qq.com",[41],{"facility":42,"status":25,"city":43,"state":44,"zip":45,"country":46,"countryCode":47,"cosmosGeoPoint":48,"geoPoint":53,"contacts":54},"Xuanwu Hospital Capital Medical University","Beijing","Beijing Municipality","100053","China","CN",{"type":49,"coordinates":50},"Point",[51,52],116.39723,39.9075,{"lat":52,"lon":51},[55],{"name":56,"role":33,"phone":38,"phoneExt":25,"email":35},"Dongfan Wang",{"type":58,"investigatorFullName":25,"investigatorTitle":25,"investigatorAffiliation":25,"oldNameTitle":25,"oldOrganization":25},"SPONSOR","100552212","a-novel-classification-of-sagittal-spinal-alignment-to-aid-surgical-planning-for-adult-spinal-deformity-100552212",false,"NCT06470152","A Novel Classification of Sagittal Spinal Alignment to Aid Surgical Planning for Adult Spinal Deformity","Pelvic Incidence-Dependent Clustering of Sagittal Spinal Alignment: A Novel Classification to Aid Surgical Planning for Adult Spinal Deformity","CSSAASD","Inclusion Criteria:\n\n1. ≥ 18 years of age at the time of treatment;\n2. Complete radiographic data, including standing posteroanterior and lateral whole-spine radiographs, lumbar computed tomography, and lumbar magnetic resonance imaging;\n3. Radiographic evidence of ASD: sagittal vertical axis ≥ 50 mm, pelvic tilt ≥ 25°, pelvic incidence-lumbar lordosis mismatch ≥ 10°, and\u002For thoracic kyphosis ≥ 60°.\n\nExclusion Criteria:\n\n1. Any type of previous spinal surgery;\n2. Other musculoskeletal problems impeding walking ability, syndromic or neuromuscular diseases such as Parkinson\\'s disease, inflammatory conditions such as ankylosing spondylitis, infectious conditions such as spinal tuberculosis, metabolic diseases such as severe osteoporosis, and\u002For serious general medical conditions such as sepsis or malignancy;\n3. Pathology of deformity as follows: post-traumatic deformity, adult idiopathic scoliosis of the thoracic spine, or de-novo lumbar scoliosis;\n4. Hip joint Kellgren-Lawrence grade ≥ II, history of hip joint and\u002For knee joint pain, and\u002For previous joint replacement.","ALL","18 Years",{"count":70,"type":71},200,"ESTIMATED","INTERVENTIONAL",[74],"NA","Surgical outcomes, including radiographic outcomes, patient-reported outcomes, postoperative complications, and revision surgery rates, were compared in patients with adult spinal deformity who underwent correction surgery with reference to our pelvic incidence-dependent (PI-dependent) clustering of sagittal spinal alignment and existing standards (sagittal age-adjusted score \\[SAAS\\], global alignment and proportion \\[GAP\\] score, and Roussouly classification). Our findings may provide tangible guidance for surgical decision-making in ASD.",[77,78,79,80],"Adult Spinal Deformity","Sagittal Deformity","Sagittal Alignment","Sagittal Imbalance","NOT_YET_RECRUITING","2024-06-17",{"date":84,"type":85},"2024-06-24","ACTUAL",{"date":87,"type":71},"2024-12-01",{"date":89,"type":71},"2027-12-01",{"name":5,"class":6},1]