[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100557660":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":25,"centralContacts":29,"locations":38,"responsibleParty":87,"collaborators":91,"id":95,"slug":96,"hasResults":97,"nctId":98,"briefTitle":99,"officialTitle":100,"acronym":101,"eligibilityCriteria":102,"healthyVolunteers":97,"sex":103,"minAge":104,"maxAge":25,"enrollmentInfo":105,"targetDuration":25,"studyType":108,"phases":109,"briefSummary":111,"conditions":112,"keywords":25,"overallStatus":60,"whyStopped":25,"lastUpdateSubmitDate":116,"lastUpdatePostDateStruct":117,"startDateStruct":120,"completionDateStruct":122,"leadSponsor":124,"locationsCount":125},{"fullName":5,"class":6},"Massachusetts General Hospital","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"SHIFT Intervention Group","EXPERIMENTAL","SHIFT is a self-administered, multi-component digital application for HCT survivors, incorporating several features to promote engagement and health behavior change, and includes gamification strategies, videos of HCT survivors, intimacy exercises, and optional content.",[13],"Behavioral: SHIFT Intervention Group",{"label":15,"type":16,"description":17,"interventionNames":18},"Enhanced Usual Care Group","ACTIVE_COMPARATOR","Patients assigned to enhanced usual care group will not receive access to the SHIFT application. They will meet with their HCT clinician and maybe referred to specialist care at the patients' request or at the discretion of the HCT clinician.",[19],"Behavioral: Enhanced Usual Care Group",[21,26],{"type":22,"name":9,"description":23,"armGroupLabels":24,"otherNames":25},"BEHAVIORAL","Participants assigned to SHIFT will meet with their HCT clinician for a brief medical examination to assess the need for medications for erectile dysfunction, vaginal atrophy, or genital graft-versus-host disease; and start using SHIFT at their desired pace over 8 weeks to complete five modules.",[9],null,{"type":22,"name":15,"description":27,"armGroupLabels":28,"otherNames":25},"Participants assigned to the enhanced usual care group will meet with their HCT clinician for a brief medical examination to assess the need for medications for erectile dysfunction, vaginal atrophy, or genital graft-versus-host disease; and maybe referred to a psychologist, urologist, or gynecologist at the participants' request or at the discretion of the HCT clinician.",[15],[30,35],{"name":31,"role":32,"phone":33,"phoneExt":25,"email":34},"Areej El-Jawahri, MD","CONTACT","617-724-4000","ael-jawahri@mgb.org",{"name":36,"role":32,"phone":25,"phoneExt":25,"email":37},"Sajeewani Samarakoon, PhD","ssamarakoon@mgh.harvard.edu",[39,58,72],{"facility":40,"status":41,"city":42,"state":43,"zip":44,"country":45,"countryCode":46,"cosmosGeoPoint":47,"geoPoint":52,"contacts":53},"University of Miami","NOT_YET_RECRUITING","Coral Gables","Florida","33124","United States","US",{"type":48,"coordinates":49},"Point",[50,51],-80.26838,25.72149,{"lat":51,"lon":50},[54],{"name":55,"role":32,"phone":56,"phoneExt":25,"email":57},"Lara Traeger, PhD","305-284-3012","ltraeger@miami.edu",{"facility":59,"status":60,"city":61,"state":62,"zip":63,"country":45,"countryCode":46,"cosmosGeoPoint":64,"geoPoint":68,"contacts":69},"Massachusetts General Hospital (MGH)","RECRUITING","Boston","Massachusetts","02114",{"type":48,"coordinates":65},[66,67],-71.05977,42.35843,{"lat":67,"lon":66},[70,71],{"name":31,"role":32,"phone":33,"phoneExt":25,"email":34},{"name":36,"role":32,"phone":25,"phoneExt":25,"email":37},{"facility":73,"status":41,"city":74,"state":75,"zip":76,"country":45,"countryCode":46,"cosmosGeoPoint":77,"geoPoint":81,"contacts":82},"Fox Chase Cancer Center","Philadelphia","Pennsylvania","19111",{"type":48,"coordinates":78},[79,80],-75.16362,39.95238,{"lat":80,"lon":79},[83],{"name":84,"role":32,"phone":85,"phoneExt":25,"email":86},"Jennifer Reese","215-214-3223","Jennifer.Reese@fccc.edu",{"type":88,"investigatorFullName":89,"investigatorTitle":90,"investigatorAffiliation":5,"oldNameTitle":25,"oldOrganization":25},"PRINCIPAL_INVESTIGATOR","El-Jawahri, Areej,M.D.","Associate Professor of Medicine",[92],{"name":93,"class":94},"National Cancer Institute (NCI)","NIH","100557660","a-novel-digital-application-shift-to-improve-outcomes-for-hematopoietic-stem-cell-transplant-survivors-100557660",false,"NCT06541002","A Novel Digital Application (SHIFT) to Improve Outcomes for Hematopoietic Stem Cell Transplant Survivors","Multi-Site Randomized Controlled Trial of a Novel Digital Application (SHIFT) to Improve Outcomes for Hematopoietic Stem Cell Transplant Survivors","SHIFT","Inclusion Criteria:\n\n* Adult patients (\\> 18 years) who underwent autologous or allogeneic HCT \\> three months prior to study enrollment\n* Screen positive for sexual health concerns causing distress based on the National Comprehensive Network (NCCN) survivorship guidelines screening questions\n\nExclusion Criteria:\n\n* Patients who do not comprehend English or Spanish since SHIFT will only be available in these two languages for this efficacy trial.\n* Patients with any major uncontrolled psychiatric disorder or other comorbid cognitive conditions, which the treating HCT clinician believes would prohibit the patients' capacity to provide informed consent and participate in study procedures.\n* Patients with relapsed disease requiring treatment.","ALL","18 Years",{"count":106,"type":107},300,"ESTIMATED","INTERVENTIONAL",[110],"NA","This research study is evaluating the efficacy of a novel self-administered digital application for improving sexual health outcomes, quality of life, and psychological distress in hematopoietic stem cell transplant survivors.",[113,114,115],"Sexual Dysfunction","Stem Cell Transplant Complications","Bone Marrow Transplant Complications","2026-03-17",{"date":118,"type":119},"2026-03-19","ACTUAL",{"date":121,"type":119},"2025-01-27",{"date":123,"type":107},"2030-04-30",{"name":5,"class":6},3]