[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100533341":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":25,"centralContacts":30,"locations":38,"responsibleParty":75,"collaborators":18,"id":78,"slug":79,"hasResults":80,"nctId":81,"briefTitle":82,"officialTitle":83,"acronym":84,"eligibilityCriteria":85,"healthyVolunteers":80,"sex":86,"minAge":87,"maxAge":18,"enrollmentInfo":88,"targetDuration":18,"studyType":91,"phases":92,"briefSummary":94,"conditions":95,"keywords":98,"overallStatus":41,"whyStopped":18,"lastUpdateSubmitDate":105,"lastUpdatePostDateStruct":106,"startDateStruct":109,"completionDateStruct":111,"leadSponsor":113,"locationsCount":114},{"fullName":5,"class":6},"Ente Ospedaliero Ospedali Galliera","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Intervention Group","EXPERIMENTAL","All the 608 patients will be evaluated by their General Practitioners through the Brief-MPI scale, which is based on the Comprehensive Geriatric Assessment (CGA).\n\nBased on the score obtained at the Brief-MPI, the patient will receive a Personalised Prevention Program (PPP) concerning the following domains: 1) motor, 2) cognitive, 3) nutritional, 4) polypharmacotherapy, 5) vaccination prevention, 6) basal and instrumental activities, 7) co-habitation. Patients will receive brochures containing practical advice and recommendations to be implemented over a 12-month period; in the case of high Brief-MPI risk scores, patients will be referred for specialist examinations and\u002For in-depth diagnostics.\n\nIn addition, saliva samples will be collected to assess biomarkers of oxidative stress and, in a subsample of 210 subjects, the composition of the oral microbiota will also be analysed.",[13],"Combination Product: Brief-MPI assessment (based on the Comprehensive Geriatric Assessment); Personalized Prevention Program",{"label":15,"type":16,"description":17,"interventionNames":18},"Control group","NO_INTERVENTION","Patients will receive the standard clinical practice by their General Practitioners, without being evaluated by the CGA or receiving the personalized prevention program (PPP). No saliva sample will be collected.",null,[20],{"type":21,"name":22,"description":23,"armGroupLabels":24,"otherNames":18},"COMBINATION_PRODUCT","Brief-MPI assessment (based on the Comprehensive Geriatric Assessment); Personalized Prevention Program","Patients will be evaluated at baseline and at 6 and 12 months after the baseline through the CGA, the Resilience Scale (RS-14 items) and the Psychological General Wellbeing Index short form.\n\nThe prevention program will be received at the baseline, so at the two follow-ups patients wiil asked the adherence to it and the level of satisfaction (Client Satisfaction Questionnaire - 8 items).\n\nSaliva sample will be collected and analyzed.",[9],[26],{"name":27,"affiliation":28,"role":29},"Alberto Pilotto","Director of the Department of Geriatric Care, orthogeroatric and rehabilitation, EO Galliera Hospital, Genova, Italy","PRINCIPAL_INVESTIGATOR",[31,35],{"name":27,"role":32,"phone":33,"phoneExt":18,"email":34},"CONTACT","0039 0105634467","alberto.pilotto@galliera.it",{"name":36,"role":32,"phone":18,"phoneExt":18,"email":37},"Marina Barbagelata","marina.barbagelata@galliera.it",[39,51,59,67],{"facility":40,"status":41,"city":42,"state":18,"zip":18,"country":43,"countryCode":44,"cosmosGeoPoint":45,"geoPoint":50,"contacts":18},"Polimedica Societa' Cooperativa","RECRUITING","Bari","Italy","IT",{"type":46,"coordinates":47},"Point",[48,49],16.86982,41.12066,{"lat":49,"lon":48},{"facility":52,"status":41,"city":53,"state":18,"zip":18,"country":43,"countryCode":44,"cosmosGeoPoint":54,"geoPoint":58,"contacts":18},"Medici Insieme Garda Valsabbia Societa' Cooperativa","Desenzano del Garda",{"type":46,"coordinates":55},[56,57],10.53559,45.47127,{"lat":57,"lon":56},{"facility":60,"status":41,"city":61,"state":18,"zip":18,"country":43,"countryCode":44,"cosmosGeoPoint":62,"geoPoint":66,"contacts":18},"Ambulatori medici","Florence",{"type":46,"coordinates":63},[64,65],11.24626,43.77925,{"lat":65,"lon":64},{"facility":68,"status":41,"city":69,"state":18,"zip":18,"country":43,"countryCode":44,"cosmosGeoPoint":70,"geoPoint":74,"contacts":18},"COMEGEN Società Cooperativa Sociale","Naples",{"type":46,"coordinates":71},[72,73],14.26811,40.85216,{"lat":73,"lon":72},{"type":76,"investigatorFullName":27,"investigatorTitle":77,"investigatorAffiliation":5,"oldNameTitle":18,"oldOrganization":18},"SPONSOR_INVESTIGATOR","Director of Department of Geriatric Care, Orthogeriatrics and Rehabilitation","100533341","a-personalized-prevention-program-ppp-based-on-the-comprehensive-geriatric-assessment-cga-for-the-prevention-of-multidimensional-frailty-related-to-non-communicable-chronic-diseases-ncds-in-older-people-100533341",false,"NCT06224556","A Personalized Prevention Program (PPP) Based on the Comprehensive Geriatric Assessment (CGA) for the Prevention of Multidimensional Frailty Related to Non-communicable Chronic Diseases (NCDs) in Older People","A Personalized Prevention Program (PPP) Based on the Comprehensive Geriatric Assessment (CGA) for the Prevention of Multidimensional Frailty Related to Non-communicable Chronic Diseases (NCDs) in Older People: a Practical Approach in Primary Care Setting","PrimaCare_P3","Inclusion Criteria:\n\n* 65 years old and over\n* At least 1 non-communicable chronic disease\n* Signed informed consent\n\nExclusion Criteria:\n\n* not willing in partecipating in the study and no signed informed consent\n* \\\u003C65 years old\n* without non-communicable chronic diseases","ALL","65 Years",{"count":89,"type":90},1216,"ESTIMATED","INTERVENTIONAL",[93],"NA","* Non-Communicable Diseases (NCDs) can accelerated the aging process and increase the frailty condition\n* The Comprehensive Geriatric Assessment (CGA) is the gold standard in the geriatric clinical context\n* Recently, in Italy the first Guidelines about the CGA in different settings for older people has been pubblicated\n* The CGA can identify older people at high risk of frailty who can benefit from a personalized prevention program\n* No studies has been investigated the effects of a personalized prevention program (PPP) based on the CGA in a primary care setting\n* The main hypothesis is that the CGA assessment can result in personalized prevention programs for older subjects in primary care settings with an effect in reducing the hospitalization rate and can be related to the biological paramters in NCDs",[96,97],"Older People","Non-Communicable Chronic Diseases",[99,100,101,102,103,104],"Primary care setting","Comprehensive Geriatric Assessment","Older people","Non-communicable chronic diseases","Personalized Prevention Program","Saliva collection","2024-08-27",{"date":107,"type":108},"2024-08-28","ACTUAL",{"date":110,"type":108},"2024-06-04",{"date":112,"type":90},"2025-05",{"name":27,"class":6},4]