[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100414544":3},{"organization":4,"armGroups":7,"interventions":13,"overallOfficials":10,"centralContacts":10,"locations":18,"responsibleParty":62,"collaborators":65,"id":88,"slug":89,"hasResults":90,"nctId":91,"briefTitle":92,"officialTitle":92,"acronym":10,"eligibilityCriteria":93,"healthyVolunteers":90,"sex":94,"minAge":95,"maxAge":10,"enrollmentInfo":96,"targetDuration":99,"studyType":100,"phases":10,"briefSummary":101,"conditions":102,"keywords":104,"overallStatus":21,"whyStopped":10,"lastUpdateSubmitDate":109,"lastUpdatePostDateStruct":110,"startDateStruct":113,"completionDateStruct":115,"leadSponsor":117,"locationsCount":118},{"fullName":5,"class":6},"Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)","OTHER",[8],{"label":9,"type":10,"description":10,"interventionNames":11},"Personalized surveillance and intervention protocol",null,[12],"Procedure: Personalized surveillance and intervention protocol",[14],{"type":15,"name":9,"description":16,"armGroupLabels":17,"otherNames":10},"PROCEDURE","This study uses one arm. Participants will undergo endoscopic surveillance with intervals between 3-6 months and 5 years, depending on severity of polyposis and performed endoscopic interventions.",[9],[19,42],{"facility":20,"status":21,"city":22,"state":23,"zip":24,"country":25,"countryCode":26,"cosmosGeoPoint":27,"geoPoint":32,"contacts":33},"MD Anderson","RECRUITING","Houston","Texas","77030","United States","US",{"type":28,"coordinates":29},"Point",[30,31],-95.36327,29.76328,{"lat":31,"lon":30},[34,39],{"name":35,"role":36,"phone":37,"phoneExt":10,"email":38},"Annie Lincoln","CONTACT","+1 919 923 4430","aglincoln@mdanderson.org",{"name":40,"role":41,"phone":10,"phoneExt":10,"email":10},"Luigi Ricciardiello","PRINCIPAL_INVESTIGATOR",{"facility":43,"status":21,"city":44,"state":45,"zip":46,"country":47,"countryCode":48,"cosmosGeoPoint":49,"geoPoint":53,"contacts":54},"Academic Medical Centre","Amsterdam","North Holland","1105AZ","Netherlands","NL",{"type":28,"coordinates":50},[51,52],4.88969,52.37403,{"lat":52,"lon":51},[55,59],{"name":56,"role":36,"phone":57,"phoneExt":10,"email":58},"Evelien Dekker, MD, PhD","0031205661260","e.dekker@amc.uva.nl",{"name":60,"role":61,"phone":10,"phoneExt":10,"email":10},"Arthur Aelvoet, MD","SUB_INVESTIGATOR",{"type":41,"investigatorFullName":63,"investigatorTitle":64,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"Prof. Evelien Dekker, MD, PhD","Prof. dr. Evelien Dekker, MD, PhD",[66,68,70,72,74,76,78,80,82,84,86],{"name":67,"class":6},"Leiden University Medical Center",{"name":69,"class":6},"The Netherlands Cancer Institute",{"name":71,"class":6},"St Mark's Hospital Foundation",{"name":73,"class":6},"Hospital Clinic of Barcelona",{"name":75,"class":6},"Maria Sklodowska-Curie National Research Institute of Oncology",{"name":77,"class":6},"Hospital General Universitario de Alicante",{"name":79,"class":6},"IRCCS Azienda Ospedaliero-Universitaria di Bologna",{"name":81,"class":6},"Radboud University Medical Center",{"name":83,"class":6},"University Hospital, Bonn",{"name":85,"class":6},"Hvidovre University Hospital",{"name":87,"class":6},"M.D. Anderson Cancer Center","100414544","a-personalized-surveillance-and-intervention-protocol-for-duodenal-and-gastric-polyposis-in-patients-with-familial-adenomatous-polyposis-100414544",false,"NCT04677998","A Personalized Surveillance and Intervention Protocol for Duodenal and Gastric Polyposis in Patients With Familial Adenomatous Polyposis","Inclusion Criteria:\n\n* Diagnosis of FAP, at least one of following: genetic diagnosis (proven APC germline mutation) and\u002For clinical diagnosis (\\>100 colorectal adenomas in combination with a positive family history of FAP)\n* Age 18 years or older\n\nExclusion Criteria:\n\n* Endoscopic removal of all polyps with an indication for removal not possible\u002Ffeasible\n* Gastric or duodenal cancer at baseline endoscopy\n* Need for surgery","ALL","18 Years",{"count":97,"type":98},1000,"ESTIMATED","5 Years","OBSERVATIONAL","The purpose of this study is to determine the efficacy and safety of a personalized surveillance and intervention protocol for duodenal and gastric polyposis in patients with familial adenomatous polyposis (FAP)",[103],"Familial Adenomatous Polyposis",[105,106,107,108],"Endoscopic surveillance","Endoscopic interventions","Personalized care","Gastrointestinal neoplasia","2026-02-20",{"date":111,"type":112},"2026-02-23","ACTUAL",{"date":114,"type":112},"2020-11-24",{"date":116,"type":98},"2027-11",{"name":5,"class":6},2]