[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100476108":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":26,"centralContacts":30,"locations":35,"responsibleParty":51,"collaborators":25,"id":53,"slug":54,"hasResults":55,"nctId":56,"briefTitle":57,"officialTitle":58,"acronym":25,"eligibilityCriteria":59,"healthyVolunteers":60,"sex":61,"minAge":62,"maxAge":63,"enrollmentInfo":64,"targetDuration":25,"studyType":67,"phases":68,"briefSummary":70,"conditions":71,"keywords":25,"overallStatus":74,"whyStopped":25,"lastUpdateSubmitDate":75,"lastUpdatePostDateStruct":76,"startDateStruct":79,"completionDateStruct":81,"leadSponsor":83,"locationsCount":84},{"fullName":5,"class":6},"Weill Medical College of Cornell University","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Patients with Aphonia or Dysphonia","EXPERIMENTAL","Participants with Aphonia or Dysphonia will be asked to recite phrases with sEMG attached to articulatory muscles.",[13],"Device: Surface Electromyography",{"label":15,"type":16,"description":17,"interventionNames":18},"Healthy Volunteers","PLACEBO_COMPARATOR","Healthy Volunteer will be asked to recite phrases with sEMG attached to articulatory muscles.",[13],[20],{"type":21,"name":22,"description":23,"armGroupLabels":24,"otherNames":25},"DEVICE","Surface Electromyography","Surface ElectroMyoGraphy (SEMG) is a non-invasive technique for measuring muscle electrical activity that occurs during muscle contraction and relaxation cycles. Electrodes will be attached with a AgCl gel to muscles used for articulation.",[15,9],null,[27],{"name":28,"affiliation":5,"role":29},"Anaïs Rameau, MD","PRINCIPAL_INVESTIGATOR",[31],{"name":28,"role":32,"phone":33,"phoneExt":25,"email":34},"CONTACT","646-962-7464","anr2783@med.cornell.edu",[36],{"facility":37,"status":25,"city":38,"state":38,"zip":39,"country":40,"countryCode":41,"cosmosGeoPoint":42,"geoPoint":47,"contacts":48},"Weill Cornell Medicine","New York","10022","United States","US",{"type":43,"coordinates":44},"Point",[45,46],-74.00597,40.71427,{"lat":46,"lon":45},[49,50],{"name":28,"role":32,"phone":33,"phoneExt":25,"email":34},{"name":28,"role":29,"phone":25,"phoneExt":25,"email":25},{"type":52,"investigatorFullName":25,"investigatorTitle":25,"investigatorAffiliation":25,"oldNameTitle":25,"oldOrganization":25},"SPONSOR","100476108","a-personalized-voice-restoration-device-for-patients-with-laryngectomy-100476108",false,"NCT05479643","A Personalized Voice Restoration Device for Patients With Laryngectomy","A Pilot Study for a Novel and Personalized Voice Restoration Device for Patients With Laryngectomy","Inclusion Criteria:\n\nGroup A: Healthy Volunteers\n\n1. Adult subjects, 18 or older\n2. Without any voice impairments\n\nGroup B: Subjects with Aphonia or Dysphonia\n\n1. Adult subjects, 18 or older\n2. Documentation of severe dysphonia and\u002For aphonia, or a GRBAS score \\> 0 (GRBAS is a scale that can be used to assess voice quality of subjects who do not have a recorded history of dysphonia or aphonia. The GRBAS scale evaluates for grade, roughness, breathiness, asthenia, and strain).\n\nExclusion Criteria:\n\n\\- Group A: Healthy Volunteers\n\n1\\. Voice impairment\n\nGroup B: Subjects with Aphonia or Dysphonia\n\n1\\. Subjects whose face muscles are entirely paralyzed",true,"ALL","18 Years","110 Years",{"count":65,"type":66},100,"ESTIMATED","INTERVENTIONAL",[69],"NA","The investigators will conduct a pilot experiment for a novel and personalized method for voice restoration using machine learning applied to surface EMG (sEMG) signal from articulatory muscles of the face and the neck allowing recognition of silent speech. The investigators predict that the use novel personalized method for voice restoration will be feasible and successful for patients.",[72,73],"Dysphonia","Aphonia","NOT_YET_RECRUITING","2026-06-12",{"date":77,"type":78},"2026-06-16","ACTUAL",{"date":80,"type":66},"2027-12-01",{"date":82,"type":66},"2031-12",{"name":5,"class":6},1]