[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100466907":3},{"organization":4,"armGroups":7,"interventions":8,"overallOfficials":7,"centralContacts":7,"locations":12,"responsibleParty":49,"collaborators":7,"id":52,"slug":53,"hasResults":54,"nctId":55,"briefTitle":56,"officialTitle":57,"acronym":7,"eligibilityCriteria":58,"healthyVolunteers":54,"sex":59,"minAge":60,"maxAge":7,"enrollmentInfo":61,"targetDuration":7,"studyType":64,"phases":65,"briefSummary":67,"conditions":68,"keywords":7,"overallStatus":15,"whyStopped":7,"lastUpdateSubmitDate":72,"lastUpdatePostDateStruct":73,"startDateStruct":76,"completionDateStruct":78,"leadSponsor":80,"locationsCount":81},{"fullName":5,"class":6},"State University of New York at Buffalo","OTHER",null,[9],{"type":6,"name":10,"description":11,"armGroupLabels":7,"otherNames":7},"Diet","Using dietary interventions as an adjuvant tool may represent an effective step toward advancing the treatment options of cancer. Dietary modifications can impact the growth and proliferation of tumors via multiple mechanisms",[13,40],{"facility":14,"status":15,"city":16,"state":17,"zip":18,"country":19,"countryCode":20,"cosmosGeoPoint":21,"geoPoint":26,"contacts":27},"University at Buffalo \u002F Great Lakes Cancer Care","RECRUITING","Buffalo","New York","14203","United States","US",{"type":22,"coordinates":23},"Point",[24,25],-78.87837,42.88645,{"lat":25,"lon":24},[28,33,37],{"name":29,"role":30,"phone":31,"phoneExt":7,"email":32},"Ashlee Lang, MPH","CONTACT","716-860-0267","alang@kaleidahealth.org",{"name":34,"role":30,"phone":35,"phoneExt":7,"email":36},"Kyle Pasquariello, MA","716-529-6470","kpasquariello@gppconline.com",{"name":38,"role":39,"phone":7,"phoneExt":7,"email":7},"Roberto Pili, MD","PRINCIPAL_INVESTIGATOR",{"facility":14,"status":15,"city":16,"state":17,"zip":41,"country":19,"countryCode":20,"cosmosGeoPoint":42,"geoPoint":44,"contacts":45},"14206",{"type":22,"coordinates":43},[24,25],{"lat":25,"lon":24},[46,47,48],{"name":29,"role":30,"phone":31,"phoneExt":7,"email":32},{"name":34,"role":30,"phone":35,"phoneExt":7,"email":36},{"name":38,"role":39,"phone":7,"phoneExt":7,"email":7},{"type":39,"investigatorFullName":50,"investigatorTitle":51,"investigatorAffiliation":5,"oldNameTitle":7,"oldOrganization":7},"Roberto Pili","Associate Dean for Cancer Research and Integrative Oncology","100466907","a-pilot-feasibility-study-of-intermittent-caloric-restriction-plus-plant-based-diet-in-cancer-patients-receiving-chemotherapy-100466907",false,"NCT05359848","A Pilot, Feasibility Study of Intermittent Caloric Restriction Plus Plant-based Diet in Cancer Patients Receiving Chemotherapy","A Pilot, Feasibility Study of Intermittent Caloric Restriction Plus Plant-based Protein Diet in Cancer Patients Receiving Chemotherapy","Inclusion Criteria:\n\n* • Histologically documented, cancer patients who are eligible to receive cytotoxic chemotherapy.\n\n  * Life expectancy of at least 6 months\n  * Adults ≥ 18 years of age\n  * Adequate hematologic, renal, and liver function as evidenced by the following:\n\n    * White blood cell (WBC) ≥ 2,500 cells\u002FμL\n    * Absolute neutrophil count (ANC) ≥ 1,000 cells\u002FμL\n    * Platelet Count ≥ 100,000 cells\u002FμL\n    * Hemoglobin (HgB) ≥ 9.0 g\u002FdL\n    * Creatinine ≤ 2.0 mg\u002FdL\n    * Total bilirubin ≤ 2 x upper limit of normal (ULN)\n    * Aspartate aminotransaminase (AST, SGOT) ≤ 2.5 x ULN\n    * Alanine aminotransaminase (ALT, SGPT) ≤ 2.5 x ULN\n\nExclusion Criteria:\n\n* • Eastern Cooperative Oncology Group (ECOG) performance status 2 or higher\n\n  * Treatment with any of the following medications or interventions within 28 days of registration:\n\n    * Systemic corticosteroids; however, use of inhaled, intranasal, and topical steroids is acceptable.\n    * High dose calcitriol \\[1,25(OH)2VitD\\] (i.e., \\> 7.0 μg\u002Fweek)\n  * Any infection requiring parenteral antibiotic therapy or causing fever (temperature \\> 100.5°F or 38.1°C) within 1 week prior to registration\n  * A known allergy, intolerance, or medical contraindication to receiving the contrast dye required for the protocol-specified CT\u002FMRI imaging\n  * Any medical intervention or other condition which, in the opinion of the Principal Investigator, could compromise adherence with study requirements or otherwise compromise the study's objectives","ALL","18 Years",{"count":62,"type":63},30,"ESTIMATED","INTERVENTIONAL",[66],"NA","Caloric restriction may alter the response to chemotherapy induced stress response and enhance its antitumor effect. This study intends to use an intermitted caloric restriction protocol with alternate days before the chemotherapy administration to enhance the cytotoxic effect generated by standard treatment of cancer.",[69,70,71],"Medical Oncology","Integrative Oncology","Medical Nutrition Therapy","2026-02-18",{"date":74,"type":75},"2026-02-20","ACTUAL",{"date":77,"type":75},"2022-04-15",{"date":79,"type":63},"2027-06-01",{"name":5,"class":6},2]