[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100585658":3},{"organization":4,"armGroups":7,"interventions":14,"overallOfficials":20,"centralContacts":24,"locations":33,"responsibleParty":63,"collaborators":19,"id":65,"slug":66,"hasResults":67,"nctId":68,"briefTitle":69,"officialTitle":70,"acronym":19,"eligibilityCriteria":71,"healthyVolunteers":67,"sex":72,"minAge":73,"maxAge":19,"enrollmentInfo":74,"targetDuration":19,"studyType":77,"phases":78,"briefSummary":80,"conditions":81,"keywords":83,"overallStatus":52,"whyStopped":19,"lastUpdateSubmitDate":87,"lastUpdatePostDateStruct":88,"startDateStruct":91,"completionDateStruct":93,"leadSponsor":95,"locationsCount":96},{"fullName":5,"class":6},"GenieBiome Limited","INDUSTRY",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"MQU10","EXPERIMENTAL","Subjects will take 1 sachet of synbiotics formula (MQU10) daily for 6 weeks",[13],"Dietary Supplement: MQU10",[15],{"type":16,"name":9,"description":17,"armGroupLabels":18,"otherNames":19},"DIETARY_SUPPLEMENT","MQU10 consists of a blend of food-grade probiotic strains (20 billion CFU daily) and prebiotic compounds.",[9],null,[21],{"name":22,"affiliation":5,"role":23},"Jessica Ching, PhD","STUDY_DIRECTOR",[25,30],{"name":26,"role":27,"phone":28,"phoneExt":19,"email":29},"Emily Fung, BSc","CONTACT","(+852) 55024661","emilyfung@g-niib.com",{"name":31,"role":27,"phone":28,"phoneExt":19,"email":32},"Pui Kuan Cheong, MPH","jcheong@g-niib.com",[34,50],{"facility":5,"status":35,"city":36,"state":19,"zip":19,"country":36,"countryCode":37,"cosmosGeoPoint":38,"geoPoint":43,"contacts":44},"NOT_YET_RECRUITING","Hong Kong","HK",{"type":39,"coordinates":40},"Point",[41,42],114.17469,22.27832,{"lat":42,"lon":41},[45,47],{"name":22,"role":27,"phone":28,"phoneExt":19,"email":46},"jessicaching@g-niib.com",{"name":48,"role":49,"phone":19,"phoneExt":19,"email":19},"Ching-Ping Dennis CHEUNG","PRINCIPAL_INVESTIGATOR",{"facility":51,"status":52,"city":36,"state":19,"zip":19,"country":36,"countryCode":37,"cosmosGeoPoint":53,"geoPoint":55,"contacts":56},"Healthymind Centre","RECRUITING",{"type":39,"coordinates":54},[41,42],{"lat":42,"lon":41},[57,61],{"name":58,"role":27,"phone":59,"phoneExt":19,"email":60},"Moko Cheung, Bsc","9740 5209","mokocheung@g-niib.com",{"name":62,"role":27,"phone":59,"phoneExt":19,"email":46},"Jessica CHING, PhD",{"type":64,"investigatorFullName":19,"investigatorTitle":19,"investigatorAffiliation":19,"oldNameTitle":19,"oldOrganization":19},"SPONSOR","100585658","a-pilot-study-of-synbiotics-in-adults-with-depressive-symptoms-100585658",false,"NCT06905223","A Pilot Study of Synbiotics in Adults With Depressive Symptoms","A Pilot Study on the Efficacy of a Synbiotic Formula (MQU10) in Improving Mood and Well-being in Adults With Mild to Moderate Depressive Symptoms","Inclusion Criteria:\n\n* Individuals aged 18 or above\n* Patient Health Questionnaire-9 (PHQ-9) score between 5 to 14\n* Literate and can complete the self-report questionnaires\n* Able to understand the consent and sign the informed consent form\n\nExclusion Criteria:\n\n* Current diagnosis of substance abuse or dependence;\n* A current or past history of bipolar disorder, manic or hypomanic episodes, schizophrenia, personality disorder, posttraumatic stress disorder (PTSD), intellectual disability, neurodegenerative disorders (e. g, Parkinson's disease) or organic mental disorder\n* Requiring immediate psychiatric care (e. g, imminently suicidal subjects) or have attempted suicide in the past 3 months\n* Use of antipsychotics, antidepressants or sedatives, unless on a stable dose in the last 4 weeks\n* History of severe organ failure, renal failure on dialysis, HIV infection\n* Active malignancy within 5 years\n* History of major surgery on the gastrointestinal tract, except cholecystectomy and appendectomy in the past 5 years\n* Night shift work\n* History of antibiotic use within 4 weeks\n* History of allergy to probiotics or lactose leading to a severe allergic reaction\n* Known pregnancy or lactating","ALL","18 Years",{"count":75,"type":76},30,"ESTIMATED","INTERVENTIONAL",[79],"NA","This study aims to explore the efficacy and safety of a synbiotic formula (MQU10) in improving mood and well-being in adults with mild to moderate depressive symptoms.",[82],"Depressive Symptoms Mild to Moderate in Severity",[84,85,86],"Depressive symptoms","Synbiotics","Adult Mood","2025-06-04",{"date":89,"type":90},"2025-06-08","ACTUAL",{"date":92,"type":90},"2025-04-03",{"date":94,"type":76},"2027-09-26",{"name":5,"class":6},2]