[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100549466":3},{"organization":4,"armGroups":7,"interventions":14,"overallOfficials":10,"centralContacts":20,"locations":26,"responsibleParty":43,"collaborators":10,"id":45,"slug":46,"hasResults":47,"nctId":48,"briefTitle":49,"officialTitle":49,"acronym":10,"eligibilityCriteria":50,"healthyVolunteers":47,"sex":51,"minAge":52,"maxAge":10,"enrollmentInfo":53,"targetDuration":56,"studyType":57,"phases":10,"briefSummary":58,"conditions":59,"keywords":10,"overallStatus":29,"whyStopped":10,"lastUpdateSubmitDate":61,"lastUpdatePostDateStruct":62,"startDateStruct":65,"completionDateStruct":67,"leadSponsor":69,"locationsCount":70},{"fullName":5,"class":6},"Second Affiliated Hospital, School of Medicine, Zhejiang University","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"The patients undergoing routine coagulation tests",null,"Part1 Phase I-Laboratory calibration. Phase II-Assay performance using clinical samples. using human biological samples already collected for routine coagulation analysis.\n\nPart2 Subject underwent surgery for acute type A aortic dissection and requires routine TEG test， residual blood samples collected for fibrinogen detection by the Clauss method and electrochemical method.",[13],"Diagnostic Test: the Electrochemical-based device",[15],{"type":16,"name":17,"description":18,"armGroupLabels":19,"otherNames":10},"DIAGNOSTIC_TEST","the Electrochemical-based device","Electrochemical-based device for rapid detection of fibrinogen is a novel POC diagnostic method, which is suitable for operating theatres and emergency rooms.",[9],[21],{"name":22,"role":23,"phone":24,"phoneExt":10,"email":25},"Fengjiang ZHANG","CONTACT","+8613858007629","zrzfj@zju.edu.cn",[27],{"facility":28,"status":29,"city":30,"state":31,"zip":32,"country":33,"countryCode":34,"cosmosGeoPoint":35,"geoPoint":40,"contacts":41},"The Second Affiliated Hospital of Zhejiang University anesthesiology department","RECRUITING","Hangzhou","Zhejiang","310009","China","CN",{"type":36,"coordinates":37},"Point",[38,39],120.16142,30.29365,{"lat":39,"lon":38},[42],{"name":22,"role":23,"phone":24,"phoneExt":10,"email":25},{"type":44,"investigatorFullName":10,"investigatorTitle":10,"investigatorAffiliation":10,"oldNameTitle":10,"oldOrganization":10},"SPONSOR","100549466","a-point-of-care-electrochemical-based-device-for-rapid-detection-of-fibrinogen-on-type-a-aortic-dissection-surgery-100549466",false,"NCT06434389","A Point-of-care Electrochemical-based Device for Rapid Detection of Fibrinogen on Type A Aortic Dissection Surgery","Part1 Phase I-Laboratory calibration. The electrochemical method was employed to detect the fibrinogen concentration of standard quality control materials with varying concentration gradients, and the corresponding current values were recorded for constructing a standard curve of fibrinogen concentration.\n\nPhase II-Assay performance using clinical samples. Subject is 18 years and underwent routine hemostasis analysis. using human biological samples already collected for routine hemostasis analysis, The samples were centrifuged at 2500g for 15 min at room temperature, to obtain PPP (residual platelet count of \\\u003C10 × 10\\^9\u002FL) and stored at-20℃used for determination by electrochemical method within 2 weeks, Each clinical sample was tested three times\n\nPart2\n\nInclusion Criteria:\n\nSubject underwent surgery for acute type A aortic dissection at our hospital, Subject is 18 years, Subject requires routine TEG measurement, Subject use human fibrinogen concentrate during surgery.\n\nExclusion Criteria:\n\nUse Extracorporeal Membrane Oxygenation after surgery, inability to obtain written informed consent","ALL","18 Years",{"count":54,"type":55},150,"ESTIMATED","1 Day","OBSERVATIONAL","This study compares the results of the existing fibrinogen concentration monitoring technology to the Electrochemical-based device, a point-of-care and rapid method,using a small amount of extra blood obtained in Type A Aortic Dissection Surgery.",[60],"Hypofibrinogenemia","2025-05-12",{"date":63,"type":64},"2025-05-15","ACTUAL",{"date":66,"type":64},"2024-06-01",{"date":68,"type":55},"2025-10-31",{"name":5,"class":6},1]