[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100555535":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":24,"centralContacts":28,"locations":37,"responsibleParty":54,"collaborators":58,"id":60,"slug":61,"hasResults":62,"nctId":63,"briefTitle":64,"officialTitle":65,"acronym":12,"eligibilityCriteria":66,"healthyVolunteers":62,"sex":67,"minAge":12,"maxAge":12,"enrollmentInfo":68,"targetDuration":12,"studyType":71,"phases":72,"briefSummary":74,"conditions":75,"keywords":77,"overallStatus":39,"whyStopped":12,"lastUpdateSubmitDate":81,"lastUpdatePostDateStruct":82,"startDateStruct":85,"completionDateStruct":87,"leadSponsor":89,"locationsCount":90},{"fullName":5,"class":6},"Vanderbilt University Medical Center","OTHER",[8,13],{"label":9,"type":10,"description":11,"interventionNames":12},"Standard Care - Comparator Arm A","NO_INTERVENTION","Standard Care, which includes a category-based risk assessment tool as part of nursing admission workflow. The prophylactic interventions in the intervention are recommended by the tool but not specifically tied to provider-facing clinical decision support.",null,{"label":14,"type":15,"description":16,"interventionNames":17},"Novel PPH Risk Prediction Model - Comparator Arm B","ACTIVE_COMPARATOR","Standard Care with addition of a recently developed, novel PPH risk prediction model.",[18],"Behavioral: Novel PPH Risk Prediction Model - Comparator Arm B",[20],{"type":21,"name":14,"description":22,"armGroupLabels":23,"otherNames":12},"BEHAVIORAL","Patients in this group will receive the standard care risk assessment with the addition of a recently developed, novel PPH risk prediction model, which will automatically calculate a patient's numerical risk of hemorrhage based on 21 risk factors. Elevated risk of hemorrhage (\\>=3% predicted risk), as predicted by the model, will be linked to clinical decision support, including a best practice advisory with recommendations presented to providers for consideration when they access the patient's electronic health record.",[14],[25],{"name":26,"affiliation":5,"role":27},"Holly Ende, MD","PRINCIPAL_INVESTIGATOR",[29,33],{"name":26,"role":30,"phone":31,"phoneExt":12,"email":32},"CONTACT","615-322-8476","holly.ende@vumc.org",{"name":34,"role":30,"phone":35,"phoneExt":12,"email":36},"Tracie Baker, CCRP","615-875-1852","tracie.d.baker@vumc.org",[38],{"facility":5,"status":39,"city":40,"state":41,"zip":42,"country":43,"countryCode":44,"cosmosGeoPoint":45,"geoPoint":50,"contacts":51},"RECRUITING","Nashville","Tennessee","37212","United States","US",{"type":46,"coordinates":47},"Point",[48,49],-86.78444,36.16589,{"lat":49,"lon":48},[52,53],{"name":26,"role":30,"phone":31,"phoneExt":12,"email":32},{"name":26,"role":27,"phone":12,"phoneExt":12,"email":12},{"type":55,"investigatorFullName":56,"investigatorTitle":57,"investigatorAffiliation":5,"oldNameTitle":12,"oldOrganization":12},"SPONSOR_INVESTIGATOR","Holly Ende","Associate Professor of Anesthesiology",[59],{"name":5,"class":6},"100555535","a-pragmatic-randomized-controlled-trial-to-predict-postpartum-hemorrhage-100555535",false,"NCT06513351","A Pragmatic Randomized Controlled Trial to Predict Postpartum Hemorrhage","Logistic Regression Prediction Model vs. Standard of Care for Prediction of Postpartum Hemorrhage - A Pragmatic Randomized Controlled Trial","Inclusion Criteria:\n\n* All vaginal and cesarean deliveries occurring at Vanderbilt University Medical Center\n\nExclusion Criteria:\n\n* All patients will be randomized at the time of admission to the obstetric service. Patients who are discharged prior to delivery will be excluded from subsequent analysis. Any patients with a pre-delivery planned hysterectomy (for placenta increta or percreta) will be excluded from the treatment algorithm and primary analysis.","FEMALE",{"count":69,"type":70},10000,"ESTIMATED","INTERVENTIONAL",[73],"NA","This research project aims to enhance the safety of childbirth by using advanced computer models to predict the risk of postpartum hemorrhage (PPH).\n\nPPH is a significant concern for mothers during and after delivery. Current risk assessment tools are basic and do not adapt to changing conditions. This study will investigate whether a new and recently validated model for predicting PPH, combined with a provider-facing Best Practice Advisory (BPA) regarding currently recommended strategies triggered by an increased predicted risk, can improve perinatal outcomes.\n\nThis study will compare the current category based risk assessment tool with a new, enhanced prediction model which calculates risk based on 21 factors, automatically updates as new information becomes available during labor and, if elevated, provides a provider-facing Best Practice Advisory (BPA) recommending consideration of strategies that are institutionally agreed to represent high-quality practice.\n\nInvestigators hypothesize that the enhanced care approach will result in improved perinatal outcomes.\n\nThe goal of the study is to improve the wellbeing of mothers during childbirth by harnessing the power of modern technology and data analysis.",[76],"Post Partum Hemorrhage",[76,78,79,80],"Cesarean Section","Vaginal Birth","Risk Prediction","2025-09-29",{"date":83,"type":84},"2025-10-01","ACTUAL",{"date":86,"type":84},"2025-01-01",{"date":88,"type":70},"2027-07",{"name":56,"class":6},1]