[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100587545":3},{"organization":4,"armGroups":7,"interventions":10,"overallOfficials":10,"centralContacts":15,"locations":25,"responsibleParty":42,"collaborators":10,"id":46,"slug":47,"hasResults":48,"nctId":49,"briefTitle":50,"officialTitle":51,"acronym":10,"eligibilityCriteria":52,"healthyVolunteers":48,"sex":53,"minAge":54,"maxAge":54,"enrollmentInfo":55,"targetDuration":10,"studyType":58,"phases":10,"briefSummary":59,"conditions":60,"keywords":62,"overallStatus":66,"whyStopped":10,"lastUpdateSubmitDate":67,"lastUpdatePostDateStruct":68,"startDateStruct":71,"completionDateStruct":73,"leadSponsor":75,"locationsCount":76},{"fullName":5,"class":6},"China-Japan Friendship Hospital","OTHER",[8,12],{"label":9,"type":10,"description":11,"interventionNames":10},"Development cohort",null,"As the development cohort, this cohort retrospectively enrolled approximately 1000 postoperative patients undergoing acute type A aortic dissection (ATAAD) surgery to establish a clinical model for predicting the risk of prolonged mechanical ventilation (PMV) after ATAAD surgery.This cohort will also be utilized to analyze the risk factors for PMV following ATAAD surgery and their impact on clinical outcomes.",{"label":13,"type":10,"description":14,"interventionNames":10},"Validation cohort","As the validation cohort, this cohort retrospectively enrolled approximately 400 patients (from January 2024 to December 2024) who underwent ATAAD surgery to validate the predictive performance of the model.",[16,21],{"name":17,"role":18,"phone":19,"phoneExt":10,"email":20},"Zhou Xiaoming, Dr","CONTACT","010-68314466","zhouxmcmu@163.com",{"name":22,"role":18,"phone":23,"phoneExt":10,"email":24},"Zhang Qin, Dr","+86 18990236167","zhangqincmu@163.com",[26],{"facility":27,"status":10,"city":28,"state":29,"zip":30,"country":31,"countryCode":32,"cosmosGeoPoint":33,"geoPoint":38,"contacts":39},"Fuwai Hospital","Beijing","Beijing Municipality","100029","China","CN",{"type":34,"coordinates":35},"Point",[36,37],116.39723,39.9075,{"lat":37,"lon":36},[40],{"name":41,"role":18,"phone":19,"phoneExt":10,"email":20},"Zhou Xiaoming",{"type":43,"investigatorFullName":44,"investigatorTitle":45,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"PRINCIPAL_INVESTIGATOR","Gang Hou","Professor","100587545","a-prediction-model-of-prolonged-mechanical-ventilation-following-acute-type-a-aortic-dissection-surgery-100587545",false,"NCT06929780","A Prediction Model of Prolonged Mechanical Ventilation Following Acute Type A Aortic Dissection Surgery","Prolonged Mechanical Ventilation Following Acute Type A Aortic Dissection Surgery: Risk Factor Analysis, Impact on Clinical Outcomes and Development of Prediction Model","Inclusion Criteria:\n\n* Age ≥18 years;\n* Diagnosis of acute type A aortic dissection (ATAAD) confirmed by computed tomography angiography and echocardiography;\n* Patients who underwent aortic surgery requiring cardiopulmonary bypass (CPB), were admitted to the surgical intensive care unit (SICU), and received mechanical ventilation.\n\nExclusion Criteria:\n\n* Reintubation;\n* Intraoperative death or failure to survive beyond 72 hours postoperatively;\n* Pregnancy;\n* Severe comorbidities (e.g., lung cancer);\n* Missing critical outcome data (e.g., short-term mortality, mechanical ventilation duration, reintubation).","ALL","18 Years",{"count":56,"type":57},1400,"ESTIMATED","OBSERVATIONAL","The goal of this observational study is to develop and validate a predictive model for prolonged mechanical ventilation (PMV) following acute type A aortic dissection (ATAAD) surgery.\n\nThe main questions it aims to answer are:\n\n1. To validate the predictive performance of the model for PMV after ATAAD surgery\n2. To assess the proportion of PMV among patients undergoing ATAAD surgery\n3. To evaluate the ICU length of stay and operative mortality in patients with PMV following ATAAD surgery",[61],"Acute Type A Aortic Dissection",[63,64,65],"Acute type A aortic dissection","Prolonged mechanical ventilation","mechanical ventilation time","NOT_YET_RECRUITING","2025-04-08",{"date":69,"type":70},"2025-04-16","ACTUAL",{"date":72,"type":57},"2025-04-10",{"date":74,"type":57},"2025-09-30",{"name":5,"class":6},1]