[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100559454":3},{"organization":4,"armGroups":7,"interventions":14,"overallOfficials":21,"centralContacts":26,"locations":20,"responsibleParty":36,"collaborators":40,"id":42,"slug":43,"hasResults":44,"nctId":45,"briefTitle":46,"officialTitle":47,"acronym":20,"eligibilityCriteria":48,"healthyVolunteers":44,"sex":49,"minAge":50,"maxAge":20,"enrollmentInfo":51,"targetDuration":20,"studyType":54,"phases":55,"briefSummary":57,"conditions":58,"keywords":61,"overallStatus":65,"whyStopped":20,"lastUpdateSubmitDate":66,"lastUpdatePostDateStruct":67,"startDateStruct":70,"completionDateStruct":72,"leadSponsor":74,"locationsCount":20},{"fullName":5,"class":6},"University of Toronto","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"Patients recruited for intervention","EXPERIMENTAL","A combination of 3Y-TZP and 5Y-TZP (IPS e.max ZirCAD Prime, Ivoclar AG) with a flexural strength of 1200MPa will be utilized for the crowns. Tooth preparation will include occlusal reduction of 1.0 to 1.2mm and rounded line angles for the rest seats within the zirconia crown and buccal and lingual reduction of 1 to 1.5mm to allow for adequate buccal and lingual contour to accommodate retentive clasp arms and minor connectors. Impressions for zirconia crowns will be made with polyvinyl siloxane on a full arch custom tray. After clinical verification crowns will be cemented with resin or resin modified glass ionomer cement",[13],"Device: Surveyed zirconia crown",[15],{"type":16,"name":17,"description":18,"armGroupLabels":19,"otherNames":20},"DEVICE","Surveyed zirconia crown","Patient recruitment will be from the patient population that presents to the undergraduate dental clinic requiring removable dental prosthesis (RPD) to replace missing teeth. Selection of abutment teeth for zirconia surveyed crowns will be similar to that currently utilized when selecting RPD abutments to be restored with either porcelain fused to metal or full metal surveyed crowns for tissue and tooth supported RPD's.",[9],null,[22],{"name":23,"affiliation":24,"role":25},"Eszter S Ganss, DDS","Faculty of Dentistry, University of Toronto","STUDY_CHAIR",[27,32],{"name":28,"role":29,"phone":30,"phoneExt":20,"email":31},"Neena L D'SOUZA, DDS","CONTACT","4163996121","neena.dsouza@dentistry.utoronto.ca",{"name":33,"role":29,"phone":34,"phoneExt":20,"email":35},"Greg S Anderson, DDS","4168648189","greg.anderson@dentistry.utoronto.ca",{"type":37,"investigatorFullName":38,"investigatorTitle":39,"investigatorAffiliation":5,"oldNameTitle":20,"oldOrganization":20},"SPONSOR_INVESTIGATOR","Neena DSouza","Co-Investigator",[41],{"name":5,"class":6},"100559454","a-prospective-clinical-trial-evaluating-outcomes-of-surveyed-zirconia-crowns-100559454",false,"NCT06564337","A Prospective Clinical Trial Evaluating Outcomes of Surveyed Zirconia Crowns","A Prospective Clinical Trial Evaluating Outcomes of Surveyed Zirconia Crowns on Removable Partial Denture Abutment Teeth","Inclusion Criteria:\n\n* Inclusion criteria: Patient recruitment will be from the adult patient population that presents to the undergraduate\u002Fgraduate prosthodontic dental clinic requiring new tooth or tissue supported removable cast dental prostheses to replace missing teeth for the following situations:\n\n  * In Kennedy Class 1 and 2 tisuue supported RPD's-Terminal abutments 3,4,5,6\n  * In Kennedy Class 3 and 4 tooth supported RPD's- any abutment teeth selected will need to be documented if selected as abutments for a surveyed crown.\n  * Selection of abutment teeth for zirconia surveyed crowns will be similar to that currently utilized when selecting cast RPD abutments to be restored with either porcelain fused to metal or full metal surveyed crowns for tissue and tooth supported cast RPD's. Identifiable data will include:\n  * RPD abutment teeth which may benefit from full coverage due to large restorations.\n  * Posterior endodontically treated teeth with inadequate marginal ridge support and\n  * Abutment teeth which require axial modification for RPD retentive and or stability elements.\n  * In situations where esthetic improvement is desirable\n  * Reasons for selection wil be documented.\n\nExclusion Criteria:\n\n* Crowns that need to be splinted; patients that decline a surveyed crown; patients under the age of 18 years; patients that decline to participate in the study.","ALL","18 Years",{"count":52,"type":53},50,"ESTIMATED","INTERVENTIONAL",[56],"NA","Zirconia has shown to be a suitable substitute for metal ceramic crowns when comparing survival, biological and technical complications. Evidence demonstrating the outcomes of surveyed zirconia crowns on removable partial denture abutments is unavailable. Zirconia as a substitute for metal ceramic is being currently used for fabricating surveyed crowns although quantitative data evaluating its efficacy is sparse. The purpose of this prospective clinical trial is to evaluate clinical outcomes when zirconia is used as a full coverage restoration on removable partial denture abutments. The study will be designed as a 3-5 year prospective observational trial in the University of Toronto undergraduate clinic in a controlled environment. Outcomes measures will include survival, biological and technical complications. Descriptive statistics will be used to summarize patient characteristics and outcomes and for categorical variables frequency and percentages will be reported. A level of significance 0.05 will be used for inferential analysis, with p-values \\\u003C 0.05 reported as statistically significant. It is expected that zirconia will demonstrate similar outcomes to traditional metal ceramic surveyed crowns.",[59,60],"Removable Partial Denture","Dental Crown",[62,63,64],"removable partial denture abutment","monolithic zirconia crown survival","surveyed zirconia crown","NOT_YET_RECRUITING","2024-08-20",{"date":68,"type":69},"2024-08-23","ACTUAL",{"date":71,"type":53},"2025-01-06",{"date":73,"type":53},"2031-12-31",{"name":38,"class":6}]