[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100446200":3},{"organization":4,"armGroups":7,"interventions":14,"overallOfficials":19,"centralContacts":23,"locations":29,"responsibleParty":75,"collaborators":10,"id":77,"slug":78,"hasResults":79,"nctId":80,"briefTitle":81,"officialTitle":82,"acronym":10,"eligibilityCriteria":83,"healthyVolunteers":79,"sex":84,"minAge":85,"maxAge":86,"enrollmentInfo":87,"targetDuration":10,"studyType":90,"phases":10,"briefSummary":91,"conditions":92,"keywords":10,"overallStatus":32,"whyStopped":10,"lastUpdateSubmitDate":94,"lastUpdatePostDateStruct":95,"startDateStruct":98,"completionDateStruct":100,"leadSponsor":102,"locationsCount":103},{"fullName":5,"class":6},"Duke University","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"Biorepository trial of children and adolescents\u002Fyoung adults (AYA)",null,"undergoing hematopoietic cell transplantation (HCT) to assess the impact of endotheliopathies in the HCT setting as a contributor of significant morbidity and mortality.",[13],"Other: Biorepository Trial",[15],{"type":6,"name":16,"description":17,"armGroupLabels":18,"otherNames":10},"Biorepository Trial","participating in this arm, peripheral blood specimen(s) will be obtained at 8 specified time-points.",[9],[20],{"name":21,"affiliation":5,"role":22},"Kris Mahadeo","PRINCIPAL_INVESTIGATOR",[24],{"name":25,"role":26,"phone":27,"phoneExt":10,"email":28},"LaTarsha Spencer","CONTACT","(919) 613-1895","latarsha.spencer@duke.edu",[30,48,61],{"facility":31,"status":32,"city":33,"state":34,"zip":35,"country":36,"countryCode":37,"cosmosGeoPoint":38,"geoPoint":43,"contacts":44},"Mayo Clinic","RECRUITING","Rochester","Minnesota","55902","United States","US",{"type":39,"coordinates":40},"Point",[41,42],-92.4699,44.02163,{"lat":42,"lon":41},[45],{"name":46,"role":26,"phone":10,"phoneExt":10,"email":47},"Mira Kohorst","kohorst.mira@mayo.edu",{"facility":5,"status":32,"city":49,"state":50,"zip":51,"country":36,"countryCode":37,"cosmosGeoPoint":52,"geoPoint":56,"contacts":57},"Durham","North Carolina","27705",{"type":39,"coordinates":53},[54,55],-78.89862,35.99403,{"lat":55,"lon":54},[58],{"name":21,"role":26,"phone":59,"phoneExt":10,"email":60},"919-668-1180","kris.mahadeo@duke.edu",{"facility":62,"status":32,"city":63,"state":64,"zip":65,"country":36,"countryCode":37,"cosmosGeoPoint":66,"geoPoint":70,"contacts":71},"MD Anderson Cancer Center","Houston","Texas","77030",{"type":39,"coordinates":67},[68,69],-95.36327,29.76328,{"lat":69,"lon":68},[72],{"name":73,"role":26,"phone":10,"phoneExt":10,"email":74},"Dristhi Ragoonanan","DRagoonanan@mdanderson.org",{"type":76,"investigatorFullName":10,"investigatorTitle":10,"investigatorAffiliation":10,"oldNameTitle":10,"oldOrganization":10},"SPONSOR","100446200","a-prospective-registry-of-pediatric-cellular-therapy-patients-at-risk-for-endothelial-dysfunction-sinusoidal-obstruction-syndrome-andor-multi-organ-dysfunction-syndrome-mods-100446200",false,"NCT05090345","A Prospective Registry of Pediatric Cellular Therapy Patients at Risk for Endothelial Dysfunction, Sinusoidal Obstruction Syndrome and\u002For Multi-Organ Dysfunction Syndrome (MODS).","Prospective Multi Center Study of Pediatric Cellular Therapy Patients at Risk for Endothelial Dysfunction, Sinusoidal Obstruction Syndrome and\u002For Multi-Organ Dysfunction Syndrome (MODS)","Inclusion Criteria:\n\n* Children, adolescents and young adults (AYA) 0-26 years of age undergoing HSCT.\n* Recipients of autologous and allogeneic HSCT.\n* Any preparative regimen.\n\nExclusion Criteria:\n\n* Any patient who does not consent\u002Fassent to participation.\n* Any patient for whom 5 mL blood sample(s) drawn at specified intervals would pose any more than minimal risk, as defined by institutional guidelines and at discretion of treating physician will be ineligible for biorepository banking.","ALL","0 Years","26 Years",{"count":88,"type":89},500,"ESTIMATED","OBSERVATIONAL","This is a prospective international multi-center registry and biorepository trial of children and adolescents\u002Fyoung adults (AYA) undergoing hematopoietic cell transplantation (HCT) to assess the impact of endotheliopathies in the HCT setting as a contributor of significant morbidity and mortality.",[93],"Hematopoietic Cell Transplantation","2026-05-28",{"date":96,"type":97},"2026-06-01","ACTUAL",{"date":99,"type":97},"2019-11-19",{"date":101,"type":89},"2028-02-05",{"name":5,"class":6},3]