[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100523691":3},{"organization":4,"armGroups":7,"interventions":22,"overallOfficials":28,"centralContacts":32,"locations":27,"responsibleParty":42,"collaborators":44,"id":49,"slug":50,"hasResults":51,"nctId":52,"briefTitle":53,"officialTitle":53,"acronym":54,"eligibilityCriteria":55,"healthyVolunteers":51,"sex":56,"minAge":57,"maxAge":58,"enrollmentInfo":59,"targetDuration":27,"studyType":62,"phases":63,"briefSummary":65,"conditions":66,"keywords":69,"overallStatus":74,"whyStopped":27,"lastUpdateSubmitDate":75,"lastUpdatePostDateStruct":76,"startDateStruct":79,"completionDateStruct":81,"leadSponsor":83,"locationsCount":27},{"fullName":5,"class":6},"Haukeland University Hospital","OTHER",[8,14,18],{"label":9,"type":10,"description":11,"interventionNames":12},"Normal voltage in LA posterior wall - PVI alone","ACTIVE_COMPARATOR","Patients with normal LA posterior wall will be assigned directly to arm 1, receiving PVI alone.",[13],"Procedure: Radio frequency ablation",{"label":15,"type":10,"description":16,"interventionNames":17},"Low voltage in LA posterior wall - PVI alone","Patients with low voltage\u002Fscar on the LA posterior wall will be randomized to arm 2, receiving PVI alone.",[13],{"label":19,"type":10,"description":20,"interventionNames":21},"Low voltage in LA posterior wall - PVI + PWI","Patients with low voltage\u002Fscar on the LA posterior wall will be randomized to arm 3, receiving PVI + PWI.",[13],[23],{"type":24,"name":25,"description":25,"armGroupLabels":26,"otherNames":27},"PROCEDURE","Radio frequency ablation",[19,15,9],null,[29],{"name":30,"affiliation":5,"role":31},"Jian Chen, MD, PhD","PRINCIPAL_INVESTIGATOR",[33,39],{"name":34,"role":35,"phone":36,"phoneExt":37,"email":38},"Kristian Wollner, MD","CONTACT","92229412","+47","wollnerkristian@gmail.com",{"name":30,"role":35,"phone":40,"phoneExt":37,"email":41},"91198931","jian.chen@helse-bergen.no",{"type":43,"investigatorFullName":27,"investigatorTitle":27,"investigatorAffiliation":27,"oldNameTitle":27,"oldOrganization":27},"SPONSOR",[45,47],{"name":46,"class":6},"St. Olavs Hospital",{"name":48,"class":6},"University Hospital of North Norway","100523691","a-prospective-study-of-repeat-ablation-in-patients-with-recurrent-persistent-atrial-fibrillation-pulmonary-vein-isolation-vs-adjunct-posterior-wall-isolation-repair-pers-af-study-100523691",false,"NCT06098989","A Prospective Study of REPeat Ablation In Patients With Recurrent PERSistent Atrial Fibrillation: Pulmonary Vein Isolation vs. Adjunct Posterior Wall Isolation (REPAIR PERS-AF Study)","REPAIR PERS-AF","Inclusion Criteria:\n\n* Symptomatic patients with persistent AF and indication for repeat ablation\n* procedure.\n* Patients with recurrent persistent AF (with a duration \\\u003C3 year, at least one episode longer than 7 days during the last 6 months and have been electrically cardioverted at least once during the last 12 months) after previous catheter ablation.\n* Patients with up to two previous catheter ablations for AF are included if the procedures only involved PVI. Previous PVI procedure(s) with both cryoablation and radiofrequency ablation are accepted.\n* Patients have taken at least one antiarrhythmic drug.\n* Patients are willing to participate in the study and sign the patient information form.\n* Age: 18-80 years old.\n* Patients must be on continuous anticoagulation with warfarin (INR 2-3) or direct oral anticoagulant for \\>4 weeks prior to the ablation.\n\nExclusion Criteria:\n\n* Patients with \\>2 ablation procedures in the LA for AF or atrial flutter\n* Previous ablation procedures for AF involving ablation strategies beyond PVI\n* Duration of persistent AF \\>3 years\n* Presence of atrial flutter or atrial tachycardia\n* Presence of an intracavitary thrombus\n* Uncontrolled heart failure\n* Severe valvular disease\n* LA diameter \\> 60 mm\n* Structural heart disease involving more than moderate valvular stenosis and\u002For\n* Insufficiencies\n* Rheumatic heart disease\n* Cardiac surgery for valvopathy or for congenital heart disease\n* Patients with contraindications to systemic anticoagulation\n* Severe renal dysfunction\n* Patients who are or may potentially be pregnant.\n* Patient not able to be followed up.","ALL","18 Years","80 Years",{"count":60,"type":61},150,"ESTIMATED","INTERVENTIONAL",[64],"NA","This study aims to investigate the best strategy for repeat ablation of recurrent persistent atrial fibrillation (AF) after previous persistent AF ablation involving pulmonary vein isolation (PVI) along. Patients with low voltage areas on the posterer wall will be randomized to PVI alone or the posterer wall isoaltion (PWI) in addition to PVI.",[67,68],"Atrial Fibrillation, Persistent","Atrial Fibrillation Recurrent",[70,71,72,73],"Atrial fibrillation","Radiofrequency ablation","Posterior wall isolation","Pulmonary vein isolation","NOT_YET_RECRUITING","2023-10-22",{"date":77,"type":78},"2023-10-25","ACTUAL",{"date":80,"type":61},"2023-11-15",{"date":82,"type":61},"2026-11-15",{"name":5,"class":6}]