[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100381403":3},{"organization":4,"armGroups":7,"interventions":17,"overallOfficials":11,"centralContacts":11,"locations":23,"responsibleParty":47,"collaborators":11,"id":49,"slug":50,"hasResults":51,"nctId":52,"briefTitle":53,"officialTitle":54,"acronym":55,"eligibilityCriteria":56,"healthyVolunteers":57,"sex":58,"minAge":59,"maxAge":60,"enrollmentInfo":61,"targetDuration":11,"studyType":64,"phases":65,"briefSummary":67,"conditions":68,"keywords":11,"overallStatus":26,"whyStopped":11,"lastUpdateSubmitDate":70,"lastUpdatePostDateStruct":71,"startDateStruct":74,"completionDateStruct":76,"leadSponsor":78,"locationsCount":79},{"fullName":5,"class":6},"Hull University Teaching Hospitals NHS Trust","OTHER_GOV",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"kinematically alignment","ACTIVE_COMPARATOR",null,[13],"Procedure: alignment types",{"label":15,"type":10,"description":11,"interventionNames":16},"mechanical alignment",[13],[18],{"type":19,"name":20,"description":21,"armGroupLabels":22,"otherNames":11},"PROCEDURE","alignment types","types of alignment mechanical versus kinematic of TKA to be studied",[9,15],[24],{"facility":25,"status":26,"city":27,"state":28,"zip":29,"country":30,"countryCode":31,"cosmosGeoPoint":32,"geoPoint":37,"contacts":38},"Hull University teaching hospitals","RECRUITING","Hull","East Yorkshire","HU3 2JZ","United Kingdom","UK",{"type":33,"coordinates":34},"Point",[35,36],-0.33525,53.7446,{"lat":36,"lon":35},[39,44],{"name":40,"role":41,"phone":42,"phoneExt":11,"email":43},"Sandeep Datir","CONTACT","07760306988","sandeep.datir@hey.nhs.uk",{"name":45,"role":41,"phone":42,"phoneExt":11,"email":46},"Vilas Sadekar","vilas.sadekar@hey.nhs.uk",{"type":48,"investigatorFullName":11,"investigatorTitle":11,"investigatorAffiliation":11,"oldNameTitle":11,"oldOrganization":11},"SPONSOR","100381403","a-randomised-control-trial-comparing-functional-outcomes-for-navigated-kinematically-aligned-tkr-versus-navigated-mechanically-aligned-tkr-100381403",false,"NCT04246138","A Randomised Control Trial Comparing Functional Outcomes for Navigated Kinematically Aligned TKR Versus Navigated Mechanically Aligned TKR","RCT Comparing Functional Outcomes for Navigated Kinematically Aligned TKR Versus Navigated Mechanically Aligned TKR","MaKKRO","Inclusion Criteria:\n\n* • Age between 18 and 90 years\n\n  * Diagnosis of degenerative osteoarthritis\n\nExclusion Criteria:\n\n* o a)Post traumatic arthritis\n\n  * b)Varus \u002Fvalgus deformity of more than 20 degrees\n\n    * flexion contracture of more than 20 degrees\n    * reduced ability to make decision like dementia patients\u002Fchildren\n  * e)if they had undergone any orthopaedic procedure to the lower limbs within the last one year\n  * h) neuromuscular or neurosensory deficiency\n  * I)inflammatory arthritis of the knee joint\n\n    * patients who suffered a complication which might influence the final outcome such as a deep infection, fracture or dysfunction of the extensor mechanism in post-operative period. However the complication rate data will be analysed and reported.\n    * pregnancy\n    * patients involved in other clinical trials within last 6 months prior to being recruited in the study",true,"ALL","18 Years","90 Years",{"count":62,"type":63},100,"ESTIMATED","INTERVENTIONAL",[66],"NA","The overall aim of the study is to compare navigated kinematically aligned total knee replacements (KA TKR) with navigated mechanically aligned TKR (MA TKR) in terms of function and ROM\n\nThe objectives are therefore:\n\n1. To compare the functional outcomes of KA TKR versus MA TKR performed using navigation technique\n2. To compare ROM and alignment of knee in the two groups",[69],"Kinematical Alignment,Mechanical Alignment, Navigation","2026-03-16",{"date":72,"type":73},"2026-03-18","ACTUAL",{"date":75,"type":73},"2018-02-18",{"date":77,"type":63},"2026-12-31",{"name":5,"class":6},1]