[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100613797":3},{"organization":4,"armGroups":7,"interventions":18,"overallOfficials":23,"centralContacts":24,"locations":30,"responsibleParty":49,"collaborators":23,"id":51,"slug":52,"hasResults":53,"nctId":54,"briefTitle":55,"officialTitle":56,"acronym":23,"eligibilityCriteria":57,"healthyVolunteers":53,"sex":58,"minAge":59,"maxAge":23,"enrollmentInfo":60,"targetDuration":23,"studyType":63,"phases":64,"briefSummary":66,"conditions":67,"keywords":23,"overallStatus":33,"whyStopped":23,"lastUpdateSubmitDate":69,"lastUpdatePostDateStruct":70,"startDateStruct":73,"completionDateStruct":75,"leadSponsor":77,"locationsCount":78},{"fullName":5,"class":6},"London North West Healthcare NHS Trust","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"TXI","ACTIVE_COMPARATOR","Participants allocated to the \"TXI\" group undergo withdrawal using Texture and Colour Enhancement Imaging",[13],"Diagnostic Test: TXI",{"label":15,"type":6,"description":16,"interventionNames":17},"White light","Participants allocated in the \"White light \" group receive withdrawal with White light",[13],[19],{"type":20,"name":9,"description":21,"armGroupLabels":22,"otherNames":23},"DIAGNOSTIC_TEST","Participants allocated to the \"TXI\" group undergo withdrawal using Texture and Colour Enhancement Imaging, while those in the \"white light\" group receive withdrawal with with high-definition white light endoscopy. Both procedures follow standardized protocols outlined in the study design.",[9,15],null,[25],{"name":26,"role":27,"phone":28,"phoneExt":23,"email":29},"Jonathan Landy, Consultant Gastroenterologist","CONTACT","020 8869 544","Jonathan.Landy@nhs.net",[31],{"facility":32,"status":33,"city":34,"state":23,"zip":35,"country":36,"countryCode":37,"cosmosGeoPoint":38,"geoPoint":43,"contacts":44},"Central Middlesex Hospital","RECRUITING","London","NW10 7NS","United Kingdom","UK",{"type":39,"coordinates":40},"Point",[41,42],-0.12574,51.50853,{"lat":42,"lon":41},[45],{"name":46,"role":27,"phone":47,"phoneExt":23,"email":48},"Landy, MRCP, PhD","44 208965 5733","jonathan.landy@nhs.net",{"type":50,"investigatorFullName":23,"investigatorTitle":23,"investigatorAffiliation":23,"oldNameTitle":23,"oldOrganization":23},"SPONSOR","100613797","a-randomised-paired-design-study-of-texture-and-colour-enhancement-imaging-txi-versus-high-definition-white-light-endoscopy-100613797",false,"NCT07271264","A Randomised Paired Design Study of Texture and Colour Enhancement Imaging (TXI) Versus High-definition White Light Endoscopy","A Randomised Paired Design Study of Texture and Colour Enhancement Imaging (TXI) Versus High-definition White Light Endoscopy for Dysplasia Detection in IBD Surveillance.","Inclusion Criteria:\n\n* Patients \\>16 with inflammatory bowel disease undergoing surveillance colonoscopy.\n* Patients with Crohn's (L2\u002FL3 Montreal classification) with \\>50% colonic involvement OR\n* Patients with ulcerative colitis with Extensive or left sided disease (E3 or E2 Montreal classification) for at least 8 years or a diagnosis of Primary sclerosing cholangitis concomitant with IBD.\n\nExclusion Criteria:\n\n* Disease duration \\\u003C8 years unless a diagnosis of PSC\n* Incomplete colonoscopy\n* BBPS \\\u003C6 or \\\u003C2 in any segment\n* MES ≥2 or any variable of the SES-CD is ≥2 or any stenosis for \\>10cm segment (above the rectum)\n* Previous colorectal resection\n* Thrombocytopaenia (platelet count \\\u003C50) or Coagulopathy precluding biopsy\n* Anticoagulation that has not been held appropriately prior to the procedure (must be held at least the morning of the procedure).\n* Pregnancy\n* Unable or unwilling to consent to study participation","ALL","16 Years",{"count":61,"type":62},219,"ESTIMATED","INTERVENTIONAL",[65],"NA","Texture and Colour Enhancement Imaging (TXI) improves texture, brightness, and colour in white-light endoscopy to highlight subtle tissue differences. Now available through the EVIS X1 system, early evidence suggests potential value in IBD. Studies show that TXI may help predict ulcerative colitis relapse and performs comparably to dye chromoendoscopy in detecting lesions, though no randomised data exist for dysplasia detection in IBD surveillance. We therefore propose a randomised paired study comparing TXI with high-definition white-light endoscopy for dysplasia detection in IBD surveillance.",[68],"IBD","2026-04-07",{"date":71,"type":72},"2026-04-13","ACTUAL",{"date":74,"type":72},"2025-12-08",{"date":76,"type":62},"2029-03-30",{"name":5,"class":6},1]