[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100608713":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":24,"centralContacts":28,"locations":34,"responsibleParty":45,"collaborators":49,"id":53,"slug":54,"hasResults":55,"nctId":56,"briefTitle":57,"officialTitle":58,"acronym":24,"eligibilityCriteria":59,"healthyVolunteers":60,"sex":61,"minAge":62,"maxAge":24,"enrollmentInfo":63,"targetDuration":24,"studyType":66,"phases":67,"briefSummary":69,"conditions":70,"keywords":77,"overallStatus":36,"whyStopped":24,"lastUpdateSubmitDate":79,"lastUpdatePostDateStruct":80,"startDateStruct":83,"completionDateStruct":85,"leadSponsor":87,"locationsCount":88},{"fullName":5,"class":6},"Changi General Hospital","OTHER",[8,15],{"label":9,"type":10,"description":11,"interventionNames":12},"Whole Body Vibration Training","EXPERIMENTAL","The WBVT would be conducted using the Galileo Vibration machine (Galileo® S 35), for 3 sessions per week for 4 weeks.\n\nThe participants would be progressed in terms of (i)vibration frequency from 15 Hz to at least 25 Hz (maximum 30 Hz for those who can tolerate) (ii)for the angles of their squats (from an approximate starting point of 20 degrees (\"mini squats\" to 45 degrees \"quarter squats\"; maximum to 90 degrees-thighs parallel to ground or \"half-squats\" for those who can tolerate); as well as (iii) increasing number of each 1-minute set (from 6 to 8 sets), while standing on the WBVT machine barefoot with both feet flat on the platform set at an amplitude of 2-3mm (according to the participant's height and body physique) with variable rest breaks (up to 1 minute) between each set for a total of 15 minutes each training session.\n\nAny missed session would be recorded. To ensure compliance, the subjects would receive a standard phone-call\u002Ftext reminder prior to the scheduled session.",[13,14],"Other: Whole Body Vibration Training","Other: Otago Exercise",{"label":16,"type":17,"description":18,"interventionNames":19},"Usual Care","ACTIVE_COMPARATOR","Participants from both arms would also be provided the exercise sheet on \"Otago exercises\" (30)and demonstrated in one session how to perform the exercises. In-person demonstration of the \"Otago exercises\" would be done upon recruitment by trained study team members, at the visit for baseline measurements and a return-demonstration would be done after. They would be instructed to perform the Otago exercises daily according to the standardized instructions stated and progressed from 10 to 15 repetitions on their own for at least 3 times a week and advised to also continue other aerobic exercises, for example, brisk walking. Participants would be given an exercise and falls diary to record their exercise participation as well as any falls that occurred during the study duration for up to 3 months.",[14],[21,25],{"type":6,"name":9,"description":22,"armGroupLabels":23,"otherNames":24},"Information already included in arm\u002Fgroup descriptions.",[9],null,{"type":6,"name":26,"description":16,"armGroupLabels":27,"otherNames":24},"Otago Exercise",[16,9],[29],{"name":30,"role":31,"phone":32,"phoneExt":24,"email":33},"Christine Yuanxin Chen, MBBS","CONTACT","+65-9030 4976","christine.chen.y.x@singhealth.com.sg",[35],{"facility":5,"status":36,"city":37,"state":24,"zip":24,"country":37,"countryCode":38,"cosmosGeoPoint":39,"geoPoint":44,"contacts":24},"RECRUITING","Singapore","SG",{"type":40,"coordinates":41},"Point",[42,43],103.85007,1.28967,{"lat":43,"lon":42},{"type":46,"investigatorFullName":47,"investigatorTitle":48,"investigatorAffiliation":5,"oldNameTitle":24,"oldOrganization":24},"PRINCIPAL_INVESTIGATOR","Christine Chen Yuanxin","Doctor",[50],{"name":51,"class":52},"BMEC Pte Ltd","UNKNOWN","100608713","a-randomized-controlled-trial-comparing-whole-body-vibration-therapy-with-usual-care-and-usual-care-to-improve-muscle-health-in-older-adults-100608713",false,"NCT07205133","A Randomized Controlled Trial Comparing Whole Body Vibration Therapy With Usual Care and Usual Care to Improve Muscle Health in Older Adults","Effectiveness of Whole Body Vibration Therapy and Usual Care Compared to Usual Care in Improving Muscle Mass, Strength and Function in Older Adults","Inclusion Criteria:\n\n* Healthy Volunteer or Patients aged 65 and above,\n* Clinical frailty Scale (CFS) score of 3-4,\n* Independently ambulating without any aid\n* willingness and consent to participate in the study and ability to travel to the study-site for the measurements and interventions, and\n* participants with no regular exercise habits (defined as less than 150mins\u002Fweek of moderate intensity aerobic exercise and less than twice a week of strengthening exercises)for past 3 months.\n\nExclusion Criteria:\n\n* current active enrolment into any Day Rehab or community exercise program,\n* contraindications to WBVT machine usage (see below),\n* diagnosis of dementia,\n* history of Diabetes Mellitus\n* BMI ≤20kg\u002Fm2,\n* recent hospital admissions within the last 3 months,\n* end stage organ failure,\n* chronic diseases which are not well managed, for example, poorly controlled hypertension,\n* New York Heart Association (NYHA) score II and above for patients with history of heart failure and\n* MUST Score ≥1.\n\nContraindications to WBVT:\n\nPRIMARY CONTRAINDICATIONS TO WBVT\n\n* Pregnancy\n* Acute thrombosis (acute vascular occlusion)\n* Artificial joints in stimulated body regions\n* Fresh fractures in stimulated body regions\n* Within 3 months post surgery\u002Fprocedure and\u002For any fresh wounds and scars in the stimulated body regions\n* or if the wound healing is not yet completely finished.\n\nSECONDARY CONTRAINDICATIONS TO WBVT\n\n* Acute inflammation of the musculoskeletal system, activated arthrosis or\n* arthropathy (e.g. acute inflammation and swelling in joints).\n* Acute tendinopathies in stimulated body regions (acute tendonitis)\n* Acute hernias (tissue ruptures)\n* Acute discopathy (acute disc-related back problem)\n* Stone disease of the bile ducts and urinary tract\n* Rheumatoid Arthritis\n* Epilepsy due to secondary risk of injury",true,"ALL","65 Years",{"count":64,"type":65},40,"ESTIMATED","INTERVENTIONAL",[68],"NA","This study is a randomized controlled trial where participants would be randomly assigned to one of 2 groups. One group would receive Whole body vibration therapy and usual care and the other group only usual care. Measurements of muscle mass, strength and function would be taken before the interventions, and at 2 other points after interventions. Differences in the outcomes between the two groups would be analysed.",[71,72,73,74,75,76],"Aging","Frailty","Sarcopenia","Muscle Strength","Muscle Function","Muscle Mass",[71,72,73,78,74,75,76],"Whole Body Vibration Therapy","2026-04-14",{"date":81,"type":82},"2026-04-15","ACTUAL",{"date":84,"type":82},"2026-01-10",{"date":86,"type":65},"2027-03-31",{"name":5,"class":6},1]