[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100598941":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":30,"centralContacts":31,"locations":30,"responsibleParty":41,"collaborators":30,"id":45,"slug":46,"hasResults":47,"nctId":48,"briefTitle":49,"officialTitle":49,"acronym":30,"eligibilityCriteria":50,"healthyVolunteers":51,"sex":52,"minAge":53,"maxAge":54,"enrollmentInfo":55,"targetDuration":30,"studyType":58,"phases":59,"briefSummary":61,"conditions":62,"keywords":30,"overallStatus":64,"whyStopped":30,"lastUpdateSubmitDate":65,"lastUpdatePostDateStruct":66,"startDateStruct":69,"completionDateStruct":71,"leadSponsor":73,"locationsCount":30},{"fullName":5,"class":6},"The First Affiliated Hospital of Guangzhou Medical University","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Prediction Model Arm","EXPERIMENTAL","Lung Cancer Risk Prediction Model Arm",[13],"Diagnostic Test: Prediction Model Arm",{"label":15,"type":16,"description":17,"interventionNames":18},"Standard Screening Arm","ACTIVE_COMPARATOR","Traditional High-Risk Factors Arm",[19],"Diagnostic Test: Standard Screening Arm",[21,26],{"type":22,"name":9,"description":23,"armGroupLabels":24,"otherNames":25},"DIAGNOSTIC_TEST","Lung cancer risk stratification via prediction model integrating: advanced age, lung cancer family history, personal cancer history, childhood coal exposure, asthma history, and food allergy history. High-risk individuals receive LDCT screening. Thoracic physicians guide management of screen-positive cases.",[9],[11],{"type":22,"name":15,"description":27,"armGroupLabels":28,"otherNames":29},"Participants are screened based on NCCN guideline criteria. High-risk individuals receive LDCT screening. Thoracic physicians guide management of screen-positive cases.",[15],[17],null,[32,37],{"name":33,"role":34,"phone":35,"phoneExt":30,"email":36},"Wenhua Liang professor, doctor","CONTACT","+86 020-83062808","liangwh1987@163.com",{"name":38,"role":34,"phone":39,"phoneExt":30,"email":40},"Huiting Wang","+86 15622132598","wangh1805657064@163.com",{"type":42,"investigatorFullName":43,"investigatorTitle":44,"investigatorAffiliation":5,"oldNameTitle":30,"oldOrganization":30},"PRINCIPAL_INVESTIGATOR","Jianxing He","Principal Investigator","100598941","a-randomized-controlled-trial-evaluating-the-effectiveness-of-a-novel-risk-stratified-screening-strategy-for-lung-cancer-100598941",false,"NCT07078032","A Randomized Controlled Trial Evaluating the Effectiveness of a Novel Risk-Stratified Screening Strategy for Lung Cancer","Inclusion Criteria:\n\n1. Residents with local household registration residing continuously in the region for ≥3 years.\n2. Aged 40-74 years at enrollment.\n\nExclusion Criteria:\n\n1. Prior diagnosis of lung cancer (histologically\u002Fcytologically confirmed)\n2. Currently receiving active treatment for any malignancy.\n3. Presence of severe comorbidities with life expectancy \\\u003C5 years\n4. Participation in any lung cancer screening program within 5 years.\n5. Functional dependency (ADL score ≤2) OR unwillingness to comply with protocol-required follow-up.\n6. Declined to provide written informed consent.",true,"ALL","40 Years","74 Years",{"count":56,"type":57},60000,"ESTIMATED","INTERVENTIONAL",[60],"NA","A nationwide population-based multi-center RCT enrolling ≥60,000 eligible residents to compare screening effectiveness between risk-prediction-model-driven and traditional guideline-based high-risk lung cancer screening strategies.",[63],"Lung Cancer Screening","NOT_YET_RECRUITING","2025-07-12",{"date":67,"type":68},"2025-07-22","ACTUAL",{"date":70,"type":57},"2025-07",{"date":72,"type":57},"2028-11",{"name":5,"class":6}]