[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100556511":3},{"organization":4,"armGroups":7,"interventions":25,"overallOfficials":35,"centralContacts":39,"locations":49,"responsibleParty":109,"collaborators":112,"id":116,"slug":117,"hasResults":118,"nctId":119,"briefTitle":120,"officialTitle":121,"acronym":122,"eligibilityCriteria":123,"healthyVolunteers":124,"sex":125,"minAge":126,"maxAge":127,"enrollmentInfo":128,"targetDuration":24,"studyType":131,"phases":132,"briefSummary":134,"conditions":135,"keywords":137,"overallStatus":52,"whyStopped":24,"lastUpdateSubmitDate":141,"lastUpdatePostDateStruct":142,"startDateStruct":145,"completionDateStruct":147,"leadSponsor":149,"locationsCount":150},{"fullName":5,"class":6},"Vanderbilt University","OTHER",[8,14,20],{"label":9,"type":10,"description":11,"interventionNames":12},"Mindfulness Program","EXPERIMENTAL","The Mindfulness Program is an online, coached intervention that teaches mindfulness activities such as calm breathing, listening, acceptance, gratitude, and compassion. Participants meet with their coach weekly for nine 30-minute, weekly sessions in which they learn mindfulness skills and practice using the mindfulness exercises between sessions. Meetings are done remotely (e.g., Zoom).",[13],"Behavioral: Mindfulness Program",{"label":15,"type":16,"description":17,"interventionNames":18},"Supportive Active Comparison","ACTIVE_COMPARATOR","The Supportive Active condition involves participants meeting remotely (e.g., Zoom) with a coach for nine 30-minute, weekly sessions during which teens discuss their thoughts and feelings about things going on in their life. Coaches are instructed to use active listening, open-ended questions, empathy, reflection, and unconditional positive regard. Between sessions, teens use expressive writing to describe and understand their thoughts and feelings about situations in their life.",[19],"Behavioral: Active Comparator",{"label":21,"type":22,"description":23,"interventionNames":24},"Control","NO_INTERVENTION","This is an assessment only control condition. Participants complete all of the same measures as do youth in the other two conditions at the same time points (i.e., baseline, post-intervention (about 10 weeks after baseline) and at a six-month follow-up.",null,[26,30],{"type":27,"name":9,"description":28,"armGroupLabels":29,"otherNames":24},"BEHAVIORAL","Online, coached mindfulness training program",[9],{"type":27,"name":31,"description":32,"armGroupLabels":33,"otherNames":34},"Active Comparator","Remote meetings with a supportive coach",[15],[15],[36],{"name":37,"affiliation":5,"role":38},"Megan M Saylor, PhD","STUDY_CHAIR",[40,45],{"name":41,"role":42,"phone":43,"phoneExt":24,"email":44},"Judith A Garber, PhD","CONTACT","6153305605","jgarber.vanderbilt@gmail.com",{"name":46,"role":42,"phone":47,"phoneExt":24,"email":48},"Steven D Hollon, PhD","6153305604","steven.d.hollon@vanderbilt.edu",[50,73,92],{"facility":51,"status":52,"city":53,"state":54,"zip":55,"country":56,"countryCode":57,"cosmosGeoPoint":58,"geoPoint":63,"contacts":64},"University of California, Los Angeles","RECRUITING","Los Angeles","California","90095","United States","US",{"type":59,"coordinates":60},"Point",[61,62],-118.24368,34.05223,{"lat":62,"lon":61},[65,69],{"name":66,"role":42,"phone":67,"phoneExt":24,"email":68},"Michelle G Craske, PhD","310-825-8403","MCraske@mednet.ucla.edu",{"name":70,"role":42,"phone":71,"phoneExt":24,"email":72},"Denise A Chavira, PhD","310-825-8466","dchavira@psych.ucla.edu",{"facility":74,"status":52,"city":75,"state":76,"zip":77,"country":56,"countryCode":57,"cosmosGeoPoint":78,"geoPoint":82,"contacts":83},"Northwestern University","Evanston","Illinois","60208",{"type":59,"coordinates":79},[80,81],-87.69006,42.04114,{"lat":81,"lon":80},[84,88],{"name":85,"role":42,"phone":86,"phoneExt":24,"email":87},"Richard E Zinbarg, PhD","847-467-2290","rzinbarg@northwestern.edu",{"name":89,"role":42,"phone":90,"phoneExt":24,"email":91},"Emma K Adam, PhD","847-467-2010","ek-adam@northwestern.edu",{"facility":5,"status":52,"city":93,"state":94,"zip":95,"country":56,"countryCode":57,"cosmosGeoPoint":96,"geoPoint":100,"contacts":101},"Nashville","Tennessee","37203-5721",{"type":59,"coordinates":97},[98,99],-86.78444,36.16589,{"lat":99,"lon":98},[102,104,105,107],{"name":41,"role":42,"phone":103,"phoneExt":24,"email":44},"615-330-5605",{"name":46,"role":42,"phone":47,"phoneExt":24,"email":48},{"name":41,"role":106,"phone":24,"phoneExt":24,"email":24},"PRINCIPAL_INVESTIGATOR",{"name":46,"role":108,"phone":24,"phoneExt":24,"email":24},"SUB_INVESTIGATOR",{"type":106,"investigatorFullName":110,"investigatorTitle":111,"investigatorAffiliation":5,"oldNameTitle":24,"oldOrganization":24},"Judith Garber","Principal Investigator",[113],{"name":114,"class":115},"National Institute of Mental Health (NIMH)","NIH","100556511","a-randomized-controlled-trial-testing-the-effect-of-the-youth-mindful-awareness-program-on-negative-affect-ymap2-100556511",false,"NCT06526052","A Randomized Controlled Trial Testing the Effect of the Youth Mindful Awareness Program on Negative Affect (YMAP2).","Targeting Negative Affect Through Mindfulness Training in Youth at Risk for Internalizing Problems (R33)","YMAP2","Inclusion Criteria:\n\n* Ages 12, 13, 14, 15, 16, 17\n* Parental Consent\n* Participant Assent\n* Live in Illinois, California, or Tennessee\n\nExclusion Criteria:\n\n* current diagnosis of an anxiety or depressive disorder with significant clinical impairment\n* current alcohol or substance use disorder\n* current serious suicidal ideation or behavior\n* lifetime diagnosis of bipolar disorder, schizophrenia, autism, conduct disorder, or developmental delay\n* reading level below 4th grade\n* not English speaking at a level that would allow them to participate in the intervention and assessments",true,"ALL","12 Years","17 Years",{"count":129,"type":130},360,"ESTIMATED","INTERVENTIONAL",[133],"NA","The goal of this randomized clinical trial is to compare the effects of an online mindfulness program to an active supportive comparison condition and a no-intervention control group on reducing and preventing mood and anxiety symptoms in at-risk youth. Youth who are high on trait negative affect will be randomized to one of the three conditions. The primary outcomes of interest are reductions in momentary negative affect and internalizing problems in adolescents ages 12 to 17 years old. All participants will be evaluated prior to being randomized, after the 9-session intervention period, and at a 6-month follow-up.\n\nThe first hypothesis is that the mindfulness intervention will predict decreases in stressor-reactive momentary negative affect and internalizing symptoms. The second hypothesis is that changes in momentary negative affect will partially account for the effects of the mindfulness intervention on internalizing symptoms.",[136,21],"Prevention",[138,139,140],"Adolescents","Mindfulness","Internalizing","2025-08-14",{"date":143,"type":144},"2025-08-20","ACTUAL",{"date":146,"type":144},"2024-04-01",{"date":148,"type":130},"2027-04",{"name":5,"class":6},3]