[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100580102":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":25,"centralContacts":30,"locations":25,"responsibleParty":36,"collaborators":25,"id":40,"slug":41,"hasResults":42,"nctId":43,"briefTitle":44,"officialTitle":45,"acronym":25,"eligibilityCriteria":46,"healthyVolunteers":42,"sex":47,"minAge":48,"maxAge":49,"enrollmentInfo":50,"targetDuration":25,"studyType":53,"phases":54,"briefSummary":56,"conditions":57,"keywords":25,"overallStatus":59,"whyStopped":25,"lastUpdateSubmitDate":60,"lastUpdatePostDateStruct":61,"startDateStruct":64,"completionDateStruct":66,"leadSponsor":68,"locationsCount":25},{"fullName":5,"class":6},"Guangzhou Medical University","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"RBS group","EXPERIMENTAL","Patients in RBS group would undergo cryobiopsy with the help of RBS",[13],"Procedure: unicorn robotic bronchoscopy system",{"label":15,"type":6,"description":16,"interventionNames":17},"Control group","Patients in control group would undergo cryobiopsy with the help of conventional navigation technology.",[18],"Procedure: Conventional navigation bronchoscopy",[20,26],{"type":21,"name":22,"description":23,"armGroupLabels":24,"otherNames":25},"PROCEDURE","unicorn robotic bronchoscopy system","cryobiopsy with the help of robotic bronchoscopy system",[9],null,{"type":21,"name":27,"description":28,"armGroupLabels":29,"otherNames":25},"Conventional navigation bronchoscopy","cryobiopsy with the help of Conventional navigation bronchoscopy",[15],[31],{"name":32,"role":33,"phone":34,"phoneExt":25,"email":35},"Changhao Zhong","CONTACT","020-81566640","vast1982@126.com",{"type":37,"investigatorFullName":38,"investigatorTitle":39,"investigatorAffiliation":5,"oldNameTitle":25,"oldOrganization":25},"PRINCIPAL_INVESTIGATOR","Li Shiyue","professor","100580102","a-real-world-case-study-evaluating-the-efficacy-and-safety-of-rbs-cryobiopsy-100580102",false,"NCT06832930","A Real-World Case Study Evaluating the Efficacy and Safety of RBS Cryobiopsy","A Real-World Case Study Evaluating the Efficacy and Safety of Bronchial Navigation Localization Device-Assisted Cryobiopsy","Inclusion Criteria:\n\n* Inclusion Criteria:\n* Patients are eligible for inclusion if they meet all of the following criteria:\n\n  1. Age ≥18 years and ≤75 years, with no gender restrictions;\n  2. Presence of a peripheral lung lesion on chest CT\n  3. Patients voluntarily agree to undergo bronchoscopy and meet the requirements for the procedure;\n  4. patients are capable of understanding the purpose of the trial, demonstrate good compliance with the examinations and follow-up, voluntarily participate in the clinical trial, and sign an informed consent form.\n\nExclusion Criteria:\n\n* Patients who meet any of the following criteria will be excluded from this study:\n\n  1. Presence of contraindications for bronchoscopy, including: active massive hemoptysis; recent myocardial infarction or unstable angina; severe cardiac or pulmonary dysfunction; severe hypertension and arrhythmias; uncorrectable bleeding tendencies or severe coagulation disorders (such as platelet count \\\u003C60×10\\^9\u002FL), uremia; severe pulmonary artery hypertension; severe superior vena cava syndrome; intracranial hypertension; acute cerebrovascular events; aortic dissection or aneurysm; multiple bullae; extreme systemic exhaustion;\n  2. Female patients who are breastfeeding, pregnant, or planning pregnancy;\n  3. Patients with electromagnetic active implantable medical devices;\n  4. Subjects allergic to anesthetics; or with a history of multiple severe allergies, hereditary allergy history;\n  5. Those who have participated in or are currently participating in drug clinical trials within 3 months before screening, or have participated in other medical device clinical trials within 30 days;\n  6. Any other conditions deemed unsuitable for participation in this clinical trial by the investigator.\n\n     Exclusion Criteria:","ALL","18 Years","75 Years",{"count":51,"type":52},200,"ESTIMATED","INTERVENTIONAL",[55],"NA","The goal of this clinical trial is tois to assess the effectiveness and safety of RBS (Robotic Bronchoscopy System)-assisted cryobiopsy in real-world clinical settings in adult patients (aged ≥18 years) with suspected pulmonary lesions requiring diagnostic bronchoscopic evaluation. The main questions it aims to answer are:\n\nDoes RBS-assisted cryobiopsy improve diagnostic yield compared to conventional non-RBS-guided cryobiopsy? Is RBS-assisted cryobiopsy associated with a lower incidence of procedure-related complications (e.g., bleeding, pneumothorax) compared to conventional methods? Researchers will compare the RBS group (patients undergoing RBS-assisted cryobiopsy) with the control group (patients undergoing cryobiopsy with conventional navigation techniques, such as ENB, VBN) to evaluate differences in diagnostic accuracy and safety outcomes.\n\nParticipants will:\n\nProvide informed consent for bronchoscopic cryobiopsy. Undergo pre-procedure imaging and clinical evaluation. Receive either RBS-assisted or conventional cryobiopsy based on clinical indication and operator discretion.\n\nBe monitored for immediate and delayed complications .",[58],"Peripheral Pulmonary Lesion","NOT_YET_RECRUITING","2025-02-12",{"date":62,"type":63},"2025-02-18","ACTUAL",{"date":65,"type":52},"2025-02-15",{"date":67,"type":52},"2025-12-31",{"name":5,"class":6}]