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Riyadh",{"type":34,"coordinates":622},[616,617],{"lat":617,"lon":616},{"facility":625,"status":28,"city":626,"state":7,"zip":7,"country":627,"countryCode":628,"cosmosGeoPoint":629,"geoPoint":633,"contacts":7},"ICO Badalona - Hospital Universitari Germans Trias i Pujol","Badalona","Spain","ES",{"type":34,"coordinates":630},[631,632],2.24741,41.45004,{"lat":632,"lon":631},{"facility":635,"status":28,"city":636,"state":7,"zip":7,"country":627,"countryCode":628,"cosmosGeoPoint":637,"geoPoint":641,"contacts":7},"Hospital de Cruces","Barakaldo",{"type":34,"coordinates":638},[639,640],-2.98813,43.29639,{"lat":640,"lon":639},{"facility":643,"status":28,"city":644,"state":7,"zip":7,"country":627,"countryCode":628,"cosmosGeoPoint":645,"geoPoint":649,"contacts":7},"Hospital Clinic de Barcelona","Barcelona",{"type":34,"coordinates":646},[647,648],2.15899,41.38879,{"lat":648,"lon":647},{"facility":651,"status":28,"city":644,"state":7,"zip":7,"country":627,"countryCode":628,"cosmosGeoPoint":652,"geoPoint":654,"contacts":7},"Hospital Universitari Vall d'Hebron",{"type":34,"coordinates":653},[647,648],{"lat":648,"lon":647},{"facility":656,"status":130,"city":657,"state":7,"zip":7,"country":627,"countryCode":628,"cosmosGeoPoint":658,"geoPoint":662,"contacts":7},"Hospital de Basurto","Bilbao",{"type":34,"coordinates":659},[660,661],-2.92528,43.26271,{"lat":661,"lon":660},{"facility":664,"status":28,"city":665,"state":7,"zip":7,"country":627,"countryCode":628,"cosmosGeoPoint":666,"geoPoint":670,"contacts":7},"Hospital Universitario Donostia","Donostia \u002F San Sebastian",{"type":34,"coordinates":667},[668,669],-1.97499,43.31283,{"lat":669,"lon":668},{"facility":672,"status":28,"city":673,"state":7,"zip":7,"country":627,"countryCode":628,"cosmosGeoPoint":674,"geoPoint":678,"contacts":7},"Hospital Universitario Virgen de la Nieves","El Palmar",{"type":34,"coordinates":675},[676,677],-0.3174,39.31305,{"lat":677,"lon":676},{"facility":680,"status":130,"city":681,"state":7,"zip":7,"country":627,"countryCode":628,"cosmosGeoPoint":682,"geoPoint":686,"contacts":7},"Hospital Universitario Juan Ramon Jimenez","Huelva",{"type":34,"coordinates":683},[684,685],-6.94004,37.26638,{"lat":685,"lon":684},{"facility":688,"status":28,"city":689,"state":7,"zip":7,"country":627,"countryCode":628,"cosmosGeoPoint":690,"geoPoint":694,"contacts":7},"Hospital Universitario de Gran Canaria Dr. Negrin","Las Palmas de Gran Canaria",{"type":34,"coordinates":691},[692,693],-15.41573,28.10178,{"lat":693,"lon":692},{"facility":696,"status":28,"city":697,"state":7,"zip":7,"country":627,"countryCode":628,"cosmosGeoPoint":698,"geoPoint":702,"contacts":7},"Hospital Lucus Augusti","Lugo",{"type":34,"coordinates":699},[700,701],-7.55602,43.00992,{"lat":701,"lon":700},{"facility":704,"status":28,"city":705,"state":7,"zip":7,"country":627,"countryCode":628,"cosmosGeoPoint":706,"geoPoint":710,"contacts":7},"Hospital Regional Universitario de Malaga","Málaga",{"type":34,"coordinates":707},[708,709],-4.42034,36.72016,{"lat":709,"lon":708},{"facility":712,"status":28,"city":713,"state":7,"zip":7,"country":627,"countryCode":628,"cosmosGeoPoint":714,"geoPoint":718,"contacts":7},"Hospital Universitario Central de Asturias","Oviedo",{"type":34,"coordinates":715},[716,717],-5.84476,43.36029,{"lat":717,"lon":716},{"facility":720,"status":28,"city":721,"state":7,"zip":7,"country":627,"countryCode":628,"cosmosGeoPoint":722,"geoPoint":726,"contacts":7},"Hospital Universitari Son Espases","Palma de Mallorca",{"type":34,"coordinates":723},[724,725],2.65024,39.56939,{"lat":725,"lon":724},{"facility":728,"status":28,"city":729,"state":7,"zip":7,"country":627,"countryCode":628,"cosmosGeoPoint":730,"geoPoint":734,"contacts":7},"Complejo Hospitalario Universitario de Santiago","Santiago de Compostela",{"type":34,"coordinates":731},[732,733],-8.54569,42.88052,{"lat":733,"lon":732},{"facility":736,"status":737,"city":110,"state":7,"zip":7,"country":738,"countryCode":739,"cosmosGeoPoint":740,"geoPoint":744,"contacts":7},"King's College Hospital","COMPLETED","United Kingdom","UK",{"type":34,"coordinates":741},[742,743],-0.12574,51.50853,{"lat":743,"lon":742},{"type":746,"investigatorFullName":7,"investigatorTitle":7,"investigatorAffiliation":7,"oldNameTitle":7,"oldOrganization":7},"SPONSOR",[748],{"name":749,"class":6},"IQVIA Pty Ltd","100498916","a-real-world-effectiveness-study-of-pegcetacoplan-in-patients-with-paroxysmal-nocturnal-hemoglobinuria-pnh-100498916",false,"NCT05776472","A Real World Effectiveness Study of Pegcetacoplan in Patients With Paroxysmal Nocturnal Hemoglobinuria (PNH)","A Single Arm, Long-term, Multicentre Observational Study to Evaluate Effectiveness of Pegcetacoplan Under Real World Conditions in Patients With Paroxysmal Nocturnal Hemoglobinuria (PNH)","COMPLETE","Inclusion Criteria:\n\n* Patients ≥18 years of age with a documented PNH diagnosis.\n* Patient started routine treatment with pegcetacoplan for PNH up to 12 months before enrollment or prescribed pegcetacoplan at enrollment. Decision to initiate treatment shall be made by the treating physician and independently from the decision to include the patient in the study.\n* Patient is willing and able to provide written informed consent to participate in the study in a manner approved by the Institutional Review Board\u002FIndependent Ethics Committee and local regulations.\n\nExclusion Criteria:\n\n* Enrollment in a concurrent clinical interventional study, or intake of an Investigational Medicinal Product (IMP), within three months prior to the start of the current pegcetacoplan treatment.\n* Initiated current treatment with pegcetacoplan in an interventional study.","ALL","18 Years",{"count":761,"type":762},200,"ESTIMATED","OBSERVATIONAL","This is a 36-month, long-term, multicenter, observational study designed to describe the real world effectiveness of pegcetacoplan in patients with PNH. Patients meeting the eligibility criteria will be enrolled in the study and followed prospectively for approximately 36 months. Patient data will be collected from start of pegcetacoplan treatment to end of follow-up. Retrospective data on pegcetacoplan will be captured from the time of pegcetacoplan treatment initiation. Pegcetacoplan treatment data will be collected for a minimum of approximately 36 months and up to a maximum of approximately 72 months, including retrospective period depending on when the patient started pegcetacoplan treatment. After pegcetacoplan treatment discontinuation, patients will remain in the study for 8 weeks to capture any AEs. The scope of the study is to collect both retrospective and prospective data. Baseline is defined as start of pegcetacoplan treatment. The main part of the study will be prospective,collecting data on effectiveness, safety (all AEs), patient- and clinician-reported outcomes and health care resource use.",[766],"Paroxysmal Nocturnal Hemoglobinuria","2026-06-30",{"date":769,"type":770},"2026-07-01","ACTUAL",{"date":772,"type":770},"2023-06-26",{"date":774,"type":762},"2029-08-21",{"name":5,"class":6},87]