[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100571339":3},{"organization":4,"armGroups":7,"interventions":8,"overallOfficials":7,"centralContacts":12,"locations":18,"responsibleParty":44,"collaborators":7,"id":48,"slug":49,"hasResults":50,"nctId":51,"briefTitle":52,"officialTitle":53,"acronym":54,"eligibilityCriteria":55,"healthyVolunteers":50,"sex":56,"minAge":7,"maxAge":7,"enrollmentInfo":57,"targetDuration":7,"studyType":60,"phases":7,"briefSummary":61,"conditions":62,"keywords":65,"overallStatus":21,"whyStopped":7,"lastUpdateSubmitDate":69,"lastUpdatePostDateStruct":70,"startDateStruct":73,"completionDateStruct":75,"leadSponsor":77,"locationsCount":78},{"fullName":5,"class":6},"Guangzhou Medical University","OTHER",null,[9],{"type":6,"name":10,"description":11,"armGroupLabels":7,"otherNames":7},"Not applicable- observational study","This is a retrospective and observational study. Not Applicable",[13],{"name":14,"role":15,"phone":16,"phoneExt":7,"email":17},"hong hai Yang","CONTACT","13711244230","bjrf2009@yahoo.com",[19,36],{"facility":20,"status":21,"city":22,"state":23,"zip":24,"country":25,"countryCode":26,"cosmosGeoPoint":27,"geoPoint":32,"contacts":33},"Guangdong Sanjiu Brain Hospital","RECRUITING","Guangzhou","Guangdong","510000","China","CN",{"type":28,"coordinates":29},"Point",[30,31],113.25,23.11667,{"lat":31,"lon":30},[34],{"name":35,"role":15,"phone":7,"phoneExt":7,"email":7},"chief physician",{"facility":37,"status":21,"city":22,"state":23,"zip":38,"country":25,"countryCode":26,"cosmosGeoPoint":39,"geoPoint":41,"contacts":42},"the First Affiliated Hospital of Guangzhou Medical University","510120",{"type":28,"coordinates":40},[30,31],{"lat":31,"lon":30},[43],{"name":35,"role":15,"phone":16,"phoneExt":7,"email":17},{"type":45,"investigatorFullName":46,"investigatorTitle":47,"investigatorAffiliation":5,"oldNameTitle":7,"oldOrganization":7},"PRINCIPAL_INVESTIGATOR","Haihong Yang, MD, Pricipal investigator","Chief Physician","100571339","a-real-world-study-on-the-treatment-of-non-small-cell-lung-cancer-with-leptomeningeal-metastasis-in-china-100571339",false,"NCT06718972","A Real-world Study on the Treatment of Non-small Cell Lung Cancer With Leptomeningeal Metastasis in China","Database of Real-world Study on the Treatment of Non-small Cell Lung Cancer With Leptomeningeal Metastasis in China","CLM-tree datab","Inclusion Criteria:\n\n* non-small cell lung cancer patients with Leptomeningeal metastases diagnosed after January 2018;\n* Patients who underwent antitumor therapy after diagnosis of LM.\n\nExclusion Criteria:\n\n* Patients with small cell lung cancer components;\n* complicated with tumors other than non-small cell lung cancer.","ALL",{"count":58,"type":59},1000,"ESTIMATED","OBSERVATIONAL","This is a retrospective and prospective study planned to include NSCLC patients with Leptomeningeal metastasis (LM) and treated with antitumor therapy after 2018, from multiple centers such as the First Affiliated Hospital of Guangzhou Medical University, Guangdong Sanjiu Brain Hospital, etc., aiming to establish a database related to the treatment strategies of LM patients, and to evaluate the efficacy (eg. Overall Survival\u002FTime to Failure) and safety of different treatment strategies of LM patients, etc., as well as the significance of concomitant testing in LM patients.",[63,64],"Meningeal Metastasis","Non-Small Cell Lung Cancer",[64,66,67,68],"meningeal metastasis","real-world study","database","2025-04-24",{"date":71,"type":72},"2025-04-27","ACTUAL",{"date":74,"type":72},"2024-09-01",{"date":76,"type":59},"2028-12-31",{"name":5,"class":6},2]