[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100640846":3},{"organization":4,"armGroups":7,"interventions":14,"overallOfficials":10,"centralContacts":18,"locations":28,"responsibleParty":45,"collaborators":10,"id":49,"slug":50,"hasResults":51,"nctId":52,"briefTitle":53,"officialTitle":54,"acronym":55,"eligibilityCriteria":56,"healthyVolunteers":51,"sex":57,"minAge":58,"maxAge":10,"enrollmentInfo":59,"targetDuration":62,"studyType":63,"phases":10,"briefSummary":64,"conditions":65,"keywords":67,"overallStatus":31,"whyStopped":10,"lastUpdateSubmitDate":71,"lastUpdatePostDateStruct":72,"startDateStruct":75,"completionDateStruct":77,"leadSponsor":79,"locationsCount":80},{"fullName":5,"class":6},"Fondazione IRCCS Policlinico San Matteo di Pavia","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"Not applicable, as this is a registry tracking all TAVI procedures performed at IRCCS Policlinico Sa",null,"Not applicable, as this is a registry tracking all TAVI procedures performed at IRCCS Policlinico San Matteo",[13],"Device: Not applicable, as this is a registry tracking all TAVI procedures performed at IRCCS Policlinico San Matteo",[15],{"type":16,"name":11,"description":11,"armGroupLabels":17,"otherNames":10},"DEVICE",[9],[19,24],{"name":20,"role":21,"phone":22,"phoneExt":10,"email":23},"Marco Ferlini, MD","CONTACT","+390382503158","m.ferlini@smatteo.pv.it",{"name":25,"role":21,"phone":26,"phoneExt":10,"email":27},"Alessia Currao, PM","+39 0382503739","a.currao@smatteo.pv.it",[29],{"facility":30,"status":31,"city":32,"state":32,"zip":33,"country":34,"countryCode":35,"cosmosGeoPoint":36,"geoPoint":41,"contacts":42},"Fondazione IRCCS Policlinico San Matteo","RECRUITING","Pavia","27100","Italy","IT",{"type":37,"coordinates":38},"Point",[39,40],9.15917,45.19205,{"lat":40,"lon":39},[43],{"name":20,"role":21,"phone":44,"phoneExt":10,"email":23},"+39 0382503158",{"type":46,"investigatorFullName":47,"investigatorTitle":48,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"PRINCIPAL_INVESTIGATOR","Marco Ferlini","Principal Investigator","100640846","a-registry-to-assess-the-efficacy-and-safety-of-transcatheter-treatment-for-aortic-valve-disease-at-the-irccs-policlinico-san-matteo-foundation-in-pavia-italy-100640846",false,"NCT07596394","A Registry to Assess the Efficacy and Safety of Transcatheter Treatment for Aortic Valve Disease at the IRCCS Policlinico San Matteo Foundation in Pavia (Italy).","A Prospective and Retrospective Registry to Assess the Efficacy and Safety of Transcatheter Treatment for Aortic Valve Disease at the IRCCS Policlinico San Matteo Foundation in Pavia (PAVI_TAVI Registry).","PAVI_TAVI","Inclusion Criteria:\n\n* Age \\> 18 years.\n* Transcatheter treatment with a bioprosthesis on native aortic valve, on degenerated aortic bioprosthesis, or on degenerated mitral prostheses\u002Frings.\n\nExclusion Criteria:\n\n* Failure to sign the informed consent.","ALL","18 Years",{"count":60,"type":61},500,"ESTIMATED","5 Years","OBSERVATIONAL","PAVI-TAVI Registry Overview\n\nThe PAVI-TAVI Registry is an observational study at Fondazione IRCCS Policlinico San Matteo in Pavia, Italy. It tracks real-world outcomes of transcatheter heart valve procedures like TAVI (for aortic stenosis), valve-in-valve (VIV), TAVI for aortic insufficiency (TAVI-IAo), and TMVR (for degenerated mitral valves) in patients over 18 years old.\n\nWho Can Join Eligible patients include adults treated with these procedures on native aortic valves, failed aortic bioprostheses, or degenerated mitral prostheses\u002Frings. The only exclusion is not providing informed consent.\n\nStudy Goals The main goal is to evaluate TAVI's safety and effectiveness over 5 years, focusing on all-cause mortality from the initial procedure. Secondary goals assess complication rates, valve function, inflammation markers, heart failure hospitalizations, heart attacks, strokes, and major cardiac events.\n\nHow It Works No experimental treatments-it's a registry collecting routine clinical data via a secure electronic system. Follow-up happens at your doctor's discretion, ideally at 3 and 12 months, then yearly (often by phone for stable cases). The study aims to enroll 500+ patients.",[66],"Severe Aortic Stenosis",[68,69,70],"aortic stenosis","TAVI","TAVR","2026-05-12",{"date":73,"type":74},"2026-05-19","ACTUAL",{"date":76,"type":74},"2021-03-16",{"date":78,"type":61},"2030-12",{"name":5,"class":6},1]