[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100610097":3},{"organization":4,"armGroups":7,"interventions":25,"overallOfficials":31,"centralContacts":40,"locations":46,"responsibleParty":91,"collaborators":95,"id":97,"slug":98,"hasResults":99,"nctId":100,"briefTitle":101,"officialTitle":102,"acronym":103,"eligibilityCriteria":104,"healthyVolunteers":105,"sex":106,"minAge":107,"maxAge":108,"enrollmentInfo":109,"targetDuration":31,"studyType":112,"phases":113,"briefSummary":115,"conditions":116,"keywords":122,"overallStatus":66,"whyStopped":31,"lastUpdateSubmitDate":134,"lastUpdatePostDateStruct":135,"startDateStruct":138,"completionDateStruct":140,"leadSponsor":142,"locationsCount":143},{"fullName":5,"class":6},"Indiana University","OTHER",[8,14,19],{"label":9,"type":10,"description":11,"interventionNames":12},"Unsweetened Sparkling Water (USW)","EXPERIMENTAL","Participants in this group will replace all sugar-sweetened sodas with flavored, unsweetened sparkling waters for 4 weeks.",[13],"Behavioral: Unsweetened Sparkling Water Replacement",{"label":15,"type":10,"description":16,"interventionNames":17},"Progressively Reduced Sugar (PRS)","Participants in this group will replace sugar-sweetened sodas with carbonated beverages that contain decreasing levels of sugar each week over a 4-week period, ending with a fully unsweetened sparkling water.",[18],"Behavioral: Progressively Reduced Sugar Beverage Replacement",{"label":20,"type":21,"description":22,"interventionNames":23},"Plain Water (PW)","ACTIVE_COMPARATOR","Participants in this group will replace all sugar-sweetened sodas with plain, still water for 4 weeks. This arm serves as a control to compare outcomes against both the unsweetened sparkling water and gradually reduced sugar beverage interventions.",[24],"Behavioral: Plain Water Replacement",[26,32,36],{"type":27,"name":28,"description":29,"armGroupLabels":30,"otherNames":31},"BEHAVIORAL","Unsweetened Sparkling Water Replacement","Participants replace all sugar-sweetened sodas with flavored, unsweetened sparkling waters for 4 weeks.",[9],null,{"type":27,"name":33,"description":34,"armGroupLabels":35,"otherNames":31},"Progressively Reduced Sugar Beverage Replacement","Participants replace sugary sodas with beverages containing gradually decreasing sugar concentrations (weekly), ending with unsweetened sparkling water.",[15],{"type":27,"name":37,"description":38,"armGroupLabels":39,"otherNames":31},"Plain Water Replacement","Participants replace all sugar-sweetened sodas with plain, still water for 4 weeks. This serves as a comparator to evaluate sensory and metabolic changes.",[20],[41],{"name":42,"role":43,"phone":44,"phoneExt":31,"email":45},"Nana Gletsu Miller, PhD","CONTACT","+1 (812) 855-9110","ngletsum@iu.edu",[47,64,77],{"facility":48,"status":49,"city":50,"state":51,"zip":52,"country":53,"countryCode":54,"cosmosGeoPoint":55,"geoPoint":60,"contacts":61},"Indiana University School of Public Health - Bloomington","NOT_YET_RECRUITING","Bloomington","Indiana","47405","United States","US",{"type":56,"coordinates":57},"Point",[58,59],-86.52639,39.16533,{"lat":59,"lon":58},[62],{"name":42,"role":43,"phone":63,"phoneExt":31,"email":45},"812-855-9110",{"facility":65,"status":66,"city":67,"state":51,"zip":68,"country":53,"countryCode":54,"cosmosGeoPoint":69,"geoPoint":73,"contacts":74},"Indiana University Hospital","RECRUITING","Indianapolis","46202",{"type":56,"coordinates":70},[71,72],-86.15804,39.76838,{"lat":72,"lon":71},[75],{"name":42,"role":43,"phone":76,"phoneExt":31,"email":45},"812-855-7643",{"facility":78,"status":66,"city":79,"state":51,"zip":80,"country":53,"countryCode":54,"cosmosGeoPoint":81,"geoPoint":85,"contacts":86},"Purdue University","West Lafayette","47907",{"type":56,"coordinates":82},[83,84],-86.90807,40.42587,{"lat":84,"lon":83},[87],{"name":88,"role":43,"phone":89,"phoneExt":31,"email":90},"Cordelia Running, PhD","765-494-2282","crunning@purdue.edu",{"type":92,"investigatorFullName":93,"investigatorTitle":94,"investigatorAffiliation":5,"oldNameTitle":31,"oldOrganization":31},"SPONSOR_INVESTIGATOR","Nana Gletsu Miller","Associate Professor, Applied Health Science, Indiana University Bloomington",[96],{"name":78,"class":6},"100610097","a-sensory-strategy-to-cut-sugary-beverages-in-africanamerican-and-latine-adolescents-100610097",false,"NCT07223151","A Sensory Strategy to Cut Sugary Beverages in African\u002FAmerican and Latine Adolescents","Trading Sugar for Sparkles in Adolescents, A Sensory Approach for Reducing Added Sugar From Sweetened Beverages","SPARKLE","Inclusion Criteria:\n\n* Adolescents ages 12 to 18 who display a \"sweet-liker\" pattern, characterized by a preference for higher concentrations of sugar in beverages, specifically identifying 0.3M (10.3% sucrose) or above as their most liked sample.\n* Have obesity (body mass index \\[BMI\\] \\> 95%). During screening, subjects' height and weight will be measured to calculate BMI, and BMI will be balanced across study arms using stratified randomization.\n* Adolescents must also indicate a willingness to drink study beverages; not currently dieting\u002Fchanging diet.\n\nExclusion Criteria:\n\n* For the primary objective. Exclusion Criteria:\n\n  * Adolescent participant is pregnant, since pregnancy affects taste perception\n  * Participant is allergic or intolerant to the items we are testing.\n\nFor the secondary objective. Exclusion Criteria:\n\n* Adolescent with type 1 or type 2 diabetes (self-declared or detected at screening visit through fasting glucose)\n* Currently consume unsweetened, sparkling water two or more times per week.\n* Adolescent participant is pregnant, since pregnancy affects taste perception\n* Participant is allergic or intolerant to the items we are testing.\n* Allergic or intolerant to the items that we are testing.",true,"ALL","12 Years","18 Years",{"count":110,"type":111},63,"ESTIMATED","INTERVENTIONAL",[114],"NA","The goal of this clinical trial is to test whether replacing sugary sodas with unsweetened, flavored sparkling waters can reduce added sugar intake and improve health in Black\u002FAfrican American and Latine adolescents with obesity who prefer sweet-tasting beverages. The main questions it aims to answer are:\n\n* Does replacing sugary sodas with water change liking for sugary drinks, and water?\n* Do shifts in liking for sweetness lead to improved diet quality and cardiometabolic health?\n\nResearchers will compare replacing sugary sodas with one of three alternative beverages: unsweetened sparkling water, plain water, and beverages with gradually reduced sugar to determine which strategy is most effective.\n\nParticipants will:\n\n* Replace sugary sodas with study drinks for 4 weeks\n* Complete taste tests to measure their liking for and sensory experience of sweetness over 8-weeks\n* Provide dietary recalls, body measurements, and blood samples over 8-weeks",[117,118,119,120,121],"Obesity, Adolescent","Dietary Sugars","Taste Perception","Insulin Resistance","Feeding Behavior",[123,124,125,119,120,126,127,128,129,130,131,132,133],"Obesity","Adolescent","Sugar-Sweetened Beverages","Sweet Taste Preference","Latine Youth","African American Youth","Dietary Intervention","Beverage Replacement","Sugar Reduction","Sensory Evaluation","Randomized Controlled Trial","2025-10-29",{"date":136,"type":137},"2025-10-31","ACTUAL",{"date":139,"type":137},"2025-07-25",{"date":141,"type":111},"2027-06",{"name":93,"class":6},3]