[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100581308":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":26,"centralContacts":30,"locations":40,"responsibleParty":62,"collaborators":26,"id":66,"slug":67,"hasResults":68,"nctId":69,"briefTitle":70,"officialTitle":70,"acronym":26,"eligibilityCriteria":71,"healthyVolunteers":68,"sex":72,"minAge":73,"maxAge":74,"enrollmentInfo":75,"targetDuration":26,"studyType":78,"phases":79,"briefSummary":81,"conditions":82,"keywords":84,"overallStatus":86,"whyStopped":26,"lastUpdateSubmitDate":87,"lastUpdatePostDateStruct":88,"startDateStruct":91,"completionDateStruct":93,"leadSponsor":95,"locationsCount":96},{"fullName":5,"class":6},"Second Affiliated Hospital, School of Medicine, Zhejiang University","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Group1:40Hz flash stimulation","EXPERIMENTAL","A one-week 40HZ flash stimulation therapy (JK-PMEG2700K light modulation glasses \\[light source\\]) using flash stimulation between 20:00 and 21:00.",[13],"Device: 40Hz light modulation glasses",{"label":15,"type":16,"description":17,"interventionNames":18},"Group2:100Hz flash stimulation","SHAM_COMPARATOR","A one-week 100HZ flash stimulation therapy (JK-PMEG2700K light modulation glasses \\[light source\\]) using flash stimulation between 20:00 and 21:00.",[19],"Device: 100Hz light modulation glasses",[21,27],{"type":22,"name":23,"description":24,"armGroupLabels":25,"otherNames":26},"DEVICE","40Hz light modulation glasses","A one-week flash stimulation therapy (JK-PMEG2700K light modulation glasses \\[light source\\]) using flash stimulation between 20:00 and 21:00.",[9],null,{"type":22,"name":28,"description":24,"armGroupLabels":29,"otherNames":26},"100Hz light modulation glasses",[15],[31,36],{"name":32,"role":33,"phone":34,"phoneExt":26,"email":35},"baorong zhang, Doctor","CONTACT","+86-13958167260","brzhang@zju.edu.cn",{"name":37,"role":33,"phone":38,"phoneExt":26,"email":39},"yang ruan, Doctor","+86-18858736151","11818236@zju.edu.cn",[41],{"facility":42,"status":26,"city":43,"state":44,"zip":45,"country":46,"countryCode":47,"cosmosGeoPoint":48,"geoPoint":53,"contacts":54},"The Second Affiliated Hospital of Zhejiang University School of Medicine","Hangzhou","Zhejiang","31000","China","CN",{"type":49,"coordinates":50},"Point",[51,52],120.16142,30.29365,{"lat":52,"lon":51},[55,58,60],{"name":56,"role":57,"phone":26,"phoneExt":26,"email":26},"jiali pu, doctor","SUB_INVESTIGATOR",{"name":59,"role":57,"phone":26,"phoneExt":26,"email":26},"jun tian, doctor",{"name":61,"role":57,"phone":26,"phoneExt":26,"email":26},"yang ruan, doctor",{"type":63,"investigatorFullName":64,"investigatorTitle":65,"investigatorAffiliation":5,"oldNameTitle":26,"oldOrganization":26},"PRINCIPAL_INVESTIGATOR","Zhang Baorong","Chief physician","100581308","a-single-blind-randomized-controlled-clinical-study-of-flash-stimulation-therapy-in-parkinsons-disease-100581308",false,"NCT06848621","A Single-blind, Randomized, Controlled Clinical Study of Flash Stimulation Therapy in Parkinson's Disease","Inclusion Criteria:\n\n1. PD patients who meet the diagnostic criteria of the International Movement Disorders Association (MDS), between the ages of 50 and 70 years, the course of disease ≤5 years, and the Hoehn \\& Yahr stage ≤3;\n2. Anti-PD drugs were taken regularly for at least one month before screening, and symptoms were stable;\n3. The fixed bedtime in the past month is between 9:00 p.m. and 1:00 a.m., and the total sleep time is ≥6 hours;\n4. Have the ability to understand and voluntarily sign informed consent;\n5. Have good compliance and are willing to complete all follow-up required by this program.\n\nExclusion Criteria:\n\n1. Secondary insomnia: including sleep disorders (restless leg syndrome, periodic limb movement disorder, sleep-related breathing disorders, etc.), physical diseases, mental disorders, psychoactive substance abuse;\n2. suffering from photosensitive dermatitis, epilepsy and other diseases that are not suitable for flash stimulation;\n3. Alcohol, coffee, or drug abusers in the past 6 months;\n4. Mental illness: such as anxiety, depression, schizophrenia and post-traumatic stress disorder caused by insomnia;\n5. Used drugs or health products that regulate sleep function or affect sleep within 14 days before enrollment or less than 5 drug half-lives;\n6. Taking drugs that may impair cognitive ability, such as anticholinergic drugs, memory enhancing drugs, etc., within 7 days before enrollment;\n7. the subject is unable to complete the test or follow-up;\n8. suffering from other neurodegenerative diseases;\n9. There are endoplants in the body that cannot be examined by MRI;\n10. Inability to lie flat;\n11. Other situations in which the researcher considers it inappropriate to participate in the study.","ALL","50 Years","70 Years",{"count":76,"type":77},48,"ESTIMATED","INTERVENTIONAL",[80],"NA","The aim of this study was to evaluate the effect of flash stimulation therapy on the function of the cerebral glymphatic system and efficacy of improving symptoms in PD patients.",[83],"Parkinson's Disease",[85],"Parkinson's disease","NOT_YET_RECRUITING","2025-02-21",{"date":89,"type":90},"2025-02-27","ACTUAL",{"date":92,"type":77},"2025-03-01",{"date":94,"type":77},"2026-12-31",{"name":5,"class":6},1]