[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100538405":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":32,"centralContacts":36,"locations":45,"responsibleParty":121,"collaborators":123,"id":129,"slug":130,"hasResults":131,"nctId":132,"briefTitle":133,"officialTitle":133,"acronym":134,"eligibilityCriteria":135,"healthyVolunteers":131,"sex":136,"minAge":137,"maxAge":138,"enrollmentInfo":139,"targetDuration":25,"studyType":142,"phases":143,"briefSummary":145,"conditions":146,"keywords":148,"overallStatus":86,"whyStopped":25,"lastUpdateSubmitDate":153,"lastUpdatePostDateStruct":154,"startDateStruct":157,"completionDateStruct":159,"leadSponsor":161,"locationsCount":162},{"fullName":5,"class":6},"Children's Hospital Medical Center, Cincinnati","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Active Treatment","ACTIVE_COMPARATOR","SCThrive is a virtual, 8-week, virtual group-based, behavioral self-management intervention that includes daily use of a companion mobile app.",[13],"Behavioral: SCThrive",{"label":15,"type":16,"description":17,"interventionNames":18},"Control Condition","PLACEBO_COMPARATOR","Participants randomized to SCHealthED will receive usual care plus 7 text messages consisting of SCD educational facts to ensure the care is uniform across sites.",[19],"Other: SCHealthED",[21,26],{"type":22,"name":23,"description":11,"armGroupLabels":24,"otherNames":25},"BEHAVIORAL","SCThrive",[9],null,{"type":6,"name":27,"description":28,"armGroupLabels":29,"otherNames":30},"SCHealthED","Standard of care plus 7 SCD educational text messages to ensure education is uniform across sites",[15],[31],"Uniform Standard Care",[33],{"name":34,"affiliation":5,"role":35},"Lori E. Crosby, PsyD","PRINCIPAL_INVESTIGATOR",[37,42],{"name":38,"role":39,"phone":40,"phoneExt":25,"email":41},"Ama Wilson, MPH","CONTACT","15136365380","Ama.Wilson@cchmc.org",{"name":43,"role":39,"phone":25,"phoneExt":25,"email":44},"Taylor Richardson, BA","Taylor.Richardson2@cchmc.org",[46,67,84,104],{"facility":47,"status":48,"city":49,"state":50,"zip":51,"country":52,"countryCode":53,"cosmosGeoPoint":54,"geoPoint":59,"contacts":60},"Nemours Children's Health","NOT_YET_RECRUITING","Wilmington","Delaware","19803","United States","US",{"type":55,"coordinates":56},"Point",[57,58],-75.54659,39.74595,{"lat":58,"lon":57},[61,65],{"name":62,"role":39,"phone":63,"phoneExt":25,"email":64},"Benjamin Bear, MSW","302-723-9331","benjamin.bear@nemours.org",{"name":66,"role":35,"phone":25,"phoneExt":25,"email":25},"Aimee Hildenbrand, PhD",{"facility":68,"status":48,"city":69,"state":70,"zip":71,"country":52,"countryCode":53,"cosmosGeoPoint":72,"geoPoint":76,"contacts":77},"Children's Healthcare of Atlanta","Atlanta","Georgia","30303",{"type":55,"coordinates":73},[74,75],-84.38798,33.749,{"lat":75,"lon":74},[78,82],{"name":79,"role":39,"phone":80,"phoneExt":25,"email":81},"Vontarius Howard","404-785-3245","Vontarius.Howard@choa.org",{"name":83,"role":35,"phone":25,"phoneExt":25,"email":25},"Soumitri Sil, PhD",{"facility":85,"status":86,"city":87,"state":88,"zip":89,"country":52,"countryCode":53,"cosmosGeoPoint":90,"geoPoint":94,"contacts":95},"Cincinnati Children's Hospital Medical Center","RECRUITING","Cincinnati","Ohio","45229",{"type":55,"coordinates":91},[92,93],-84.51439,39.12711,{"lat":93,"lon":92},[96,100,103],{"name":97,"role":39,"phone":98,"phoneExt":25,"email":99},"Lori Crosby, PsyD","513-636-5380","lori.crosby@cchmc.org",{"name":38,"role":39,"phone":101,"phoneExt":25,"email":102},"513-803-0917","ama.wilson@cchmc.org",{"name":97,"role":35,"phone":25,"phoneExt":25,"email":25},{"facility":105,"status":48,"city":106,"state":107,"zip":108,"country":52,"countryCode":53,"cosmosGeoPoint":109,"geoPoint":113,"contacts":114},"Children's Hospital of Philadelphia","Philadelphia","Pennsylvania","19104",{"type":55,"coordinates":110},[111,112],-75.16362,39.95238,{"lat":112,"lon":111},[115,119],{"name":116,"role":39,"phone":117,"phoneExt":25,"email":118},"Polina Poliakova","267-426-0355","poliakovap@chop.edu",{"name":120,"role":35,"phone":25,"phoneExt":25,"email":25},"Lisa Schwartz, PhD",{"type":122,"investigatorFullName":25,"investigatorTitle":25,"investigatorAffiliation":25,"oldNameTitle":25,"oldOrganization":25},"SPONSOR",[124,126,128],{"name":125,"class":6},"Nemours Children's Health System",{"name":127,"class":6},"Emory University",{"name":105,"class":6},"100538405","a-socio-ecological-approach-for-improving-self-management-in-adolescents-with-scd-100538405",false,"NCT06290401","A Socio-ecological Approach for Improving Self-management in Adolescents With SCD","SC-Thrive","Inclusion Criteria:\n\n* Patient of a participating SCD Clinic\n* Confirmed diagnosis of SCD\n* 13-21 years of age\n\nExclusion Criteria:\n\n* Another chronic disease (which would complicate measurement of patient activation)\n* Non-English-speaking\n* Cognitive or psychiatric disorder that the physician or study therapists believe would impair study participation.","ALL","13 Years","21 Years",{"count":140,"type":141},310,"ESTIMATED","INTERVENTIONAL",[144],"NA","The goal of this clinical trial is to evaluate the impact of SCThrive (a behavioral self-management intervention) on patient activation, self-management behaviors, daily functioning, and emergency room visits in 260 adolescents and young adults with sickle cell disease (SCD) ages 13-21 receiving care at 1 of 4 pediatric SCD clinics.\n\nThe main question\\[s\\]it aims to answer are:\n\n* Does SCThrive improve patient activation?\n* Does SCThrive improve self-management behaviors, daily functioning, and decrease emergency room visits?\n* Are any improvements maintained 3 months after treatment?\n\nParticipants will complete self-management related surveys before, after, and 3 months following their participation in an 8- week, virtual group intervention with an accompanying mobile app (SCThrive).\n\nResearchers will compare outcomes for participants who receive SCThrive and participants who receive uniform standard care (SCHealthED which = standard of care plus SCD educational text messages) to see if there are differences in patient activation, self-management behaviors, daily functioning, and emergency room visits.",[147],"Anemia, Sickle Cell",[149,150,151,152],"adolescent and young adult (AYA)","self-management","behavioral intervention","sickle cell disease","2026-05-06",{"date":155,"type":156},"2026-05-11","ACTUAL",{"date":158,"type":156},"2025-02-03",{"date":160,"type":141},"2028-06-30",{"name":5,"class":6},4]