[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100551885":3},{"organization":4,"armGroups":7,"interventions":37,"overallOfficials":48,"centralContacts":52,"locations":61,"responsibleParty":183,"collaborators":185,"id":190,"slug":191,"hasResults":192,"nctId":193,"briefTitle":194,"officialTitle":195,"acronym":196,"eligibilityCriteria":197,"healthyVolunteers":192,"sex":198,"minAge":199,"maxAge":41,"enrollmentInfo":200,"targetDuration":41,"studyType":203,"phases":204,"briefSummary":206,"conditions":207,"keywords":209,"overallStatus":214,"whyStopped":41,"lastUpdateSubmitDate":215,"lastUpdatePostDateStruct":216,"startDateStruct":219,"completionDateStruct":221,"leadSponsor":223,"locationsCount":224},{"fullName":5,"class":6},"University of Birmingham","OTHER",[8,14,19,24,28,33],{"label":9,"type":10,"description":11,"interventionNames":12},"Intervention: Chlorhexidine Gluconate 2.0% to 4.0% (e.g. Hibiscrub) preoperative shower","EXPERIMENTAL","Chlorhexidine Gluconate preoperative shower (e.g. hibiscrub)\n\nThe participant may prepare themselves by undertaking whole-body disinfection with Chlorhexidine Gluconate.\n\nOn two occasions, usually the day before and the day of the operation, the participant, should wash their whole body. Research teams will remind the participant that they must complete the pre-operative washes before they arrive at theatre.\n\nFinally the whole body should be rinsed and dried thoroughly.",[13],"Other: Chlorhexidine Gluconate 2.0% to 4.0% (e.g. Hibiscrub) preoperative shower",{"label":15,"type":16,"description":17,"interventionNames":18},"Comparator: Standard preoperative preparation","ACTIVE_COMPARATOR","Standard of care means whatever pre-operative cleansing is mandated according to local hospital policy.",[13],{"label":20,"type":10,"description":21,"interventionNames":22},"Intervention: Intraoperative wound wash (e.g. Granudacyn)","Hypochlorous acid (HOCl) and Sodium hypochlorite (NaOCl) topical wound wash (e.g. Granudacyn)",[23],"Other: Intraoperative wound wash (e.g. Granudacyn)",{"label":25,"type":16,"description":26,"interventionNames":27},"Comparator: Standard intraoperative preparation","Standard of care means whatever irrigation of the wound site is mandated according to local hospital policy.",[23],{"label":29,"type":10,"description":30,"interventionNames":31},"Intervention: DACC surgical wound dressing (e.g. Leukomed Sorbact)","Leukomed Sorbact (Essity), is a sterile, single-use, bacteria-binding, adhesive-bordered wound dressing. It is used to prevent SSI in closed surgical wounds that have dry to low exudate.",[32],"Other: DACC surgical wound dressing (e.g. Leukomed Sorbact)",{"label":34,"type":16,"description":35,"interventionNames":36},"Comparator: Standard post-operative wound care","Standard of care means whatever dressing of the wound site is mandated according to local hospital policy (including no dressing). Centres mandating an active wound dressing will be excluded from the trial.",[32],[38,42,45],{"type":6,"name":39,"description":39,"armGroupLabels":40,"otherNames":41},"Chlorhexidine Gluconate 2.0% to 4.0% (e.g. Hibiscrub) preoperative shower",[15,9],null,{"type":6,"name":43,"description":43,"armGroupLabels":44,"otherNames":41},"Intraoperative wound wash (e.g. Granudacyn)",[25,20],{"type":6,"name":46,"description":46,"armGroupLabels":47,"otherNames":41},"DACC surgical wound dressing (e.g. Leukomed Sorbact)",[34,29],[49],{"name":50,"affiliation":5,"role":51},"Thomas Pinkney","PRINCIPAL_INVESTIGATOR",[53,58],{"name":54,"role":55,"phone":56,"phoneExt":41,"email":57},"Rachel Lillywhite","CONTACT","+44 (0)121 415 9103","r.e.lillywhite@bham.ac.uk",{"name":59,"role":55,"phone":56,"phoneExt":41,"email":60},"Divya Kapoor","d.kapoor@bham.ac.uk",[62,80,97,115,132,149,166],{"facility":63,"status":41,"city":64,"state":41,"zip":41,"country":65,"countryCode":66,"cosmosGeoPoint":67,"geoPoint":72,"contacts":73},"University of Abomey-Calavi","Abomey-Calavi","Benin","BJ",{"type":68,"coordinates":69},"Point",[70,71],2.35566,6.44852,{"lat":71,"lon":70},[74,77],{"name":75,"role":55,"phone":41,"phoneExt":41,"email":76},"Ismail Lawani","ismaillawani@gmail.com",{"name":78,"role":55,"phone":41,"phoneExt":41,"email":79},"Souliath Lawani","tatasouli@gmail.com",{"facility":81,"status":41,"city":82,"state":41,"zip":41,"country":83,"countryCode":84,"cosmosGeoPoint":85,"geoPoint":89,"contacts":90},"Tamale Teaching Hospital","Tamale","Ghana","GH",{"type":68,"coordinates":86},[87,88],-0.8393,9.40079,{"lat":88,"lon":87},[91,94],{"name":92,"role":55,"phone":41,"phoneExt":41,"email":93},"Stephen Tabiri","kstephenba14@gmail.com",{"name":95,"role":55,"phone":41,"phoneExt":41,"email":96},"Jane Acquaye","maame.jenny@yahoo.com",{"facility":98,"status":41,"city":99,"state":41,"zip":100,"country":101,"countryCode":102,"cosmosGeoPoint":103,"geoPoint":107,"contacts":108},"Christian Medical College (CMC) & Hospital, Ludhiana","Ludhiana","141008","India","IN",{"type":68,"coordinates":104},[105,106],75.85379,30.91204,{"lat":106,"lon":105},[109,112],{"name":110,"role":55,"phone":41,"phoneExt":41,"email":111},"Parvez Hacque","pdhaque@gmail.com",{"name":113,"role":55,"phone":41,"phoneExt":41,"email":114},"Atul Suroy","atulsuroy@gmail.com",{"facility":116,"status":41,"city":117,"state":41,"zip":118,"country":119,"countryCode":120,"cosmosGeoPoint":121,"geoPoint":125,"contacts":126},"Hospital Espanola Veracruz","Veracruz","91700","Mexico","MX",{"type":68,"coordinates":122},[123,124],-96.1429,19.18095,{"lat":124,"lon":123},[127,129],{"name":128,"role":55,"phone":41,"phoneExt":41,"email":41},"Antonio Ramos",{"name":130,"role":55,"phone":41,"phoneExt":41,"email":131},"Laura Martinez","martinez.laura@heveracruz.mx",{"facility":133,"status":41,"city":134,"state":41,"zip":41,"country":135,"countryCode":136,"cosmosGeoPoint":137,"geoPoint":141,"contacts":142},"Lagos University Teaching Hospital (Hub)","Lagos","Nigeria","NG",{"type":68,"coordinates":138},[139,140],3.39467,6.45407,{"lat":140,"lon":139},[143,146],{"name":144,"role":55,"phone":41,"phoneExt":41,"email":145},"Adesoji Ademuyiwa","adesojiademuyiwa@yahoo.co.uk",{"name":147,"role":55,"phone":41,"phoneExt":41,"email":148},"Emmanuel Williams","nihr.gsu.lagoshub@gmail.com",{"facility":150,"status":41,"city":151,"state":41,"zip":41,"country":152,"countryCode":153,"cosmosGeoPoint":154,"geoPoint":158,"contacts":159},"University Teaching Hospital of Kigali (Hub)","Kigali","Rwanda","RW",{"type":68,"coordinates":155},[156,157],30.05885,-1.94995,{"lat":157,"lon":156},[160,163],{"name":161,"role":55,"phone":41,"phoneExt":41,"email":162},"JC Allen Ingabire","ijea2000@gmail.com",{"name":164,"role":55,"phone":41,"phoneExt":41,"email":165},"Jean Pierre Nganabashaka","nganajp@gmail.com",{"facility":167,"status":41,"city":168,"state":41,"zip":41,"country":169,"countryCode":170,"cosmosGeoPoint":171,"geoPoint":175,"contacts":176},"University of the Witwatersrand","Johannesburg","South Africa","ZA",{"type":68,"coordinates":172},[173,174],28.04363,-26.20227,{"lat":174,"lon":173},[177,180],{"name":178,"role":55,"phone":41,"phoneExt":41,"email":179},"Richard Crawford","richard.crawford@wits.ac.za",{"name":181,"role":55,"phone":41,"phoneExt":41,"email":182},"Matshego Nkwana","matshego.nkwana@wits.ac.za",{"type":184,"investigatorFullName":41,"investigatorTitle":41,"investigatorAffiliation":41,"oldNameTitle":41,"oldOrganization":41},"SPONSOR",[186,188],{"name":187,"class":6},"Kigali University Teaching Hospital",{"name":189,"class":6},"Université d'Abomey-Calavi","100551885","a-stratified-multi-arm-multi-site-randomised-platform-trial-aiming-to-reduce-the-incidence-of-post-operative-ssi-100551885",false,"NCT06465901","A Stratified, Multi-ARm, muLti-site Randomised Platform Trial Aiming to Reduce the INcidence of Post-operative SSI","MARLIN: Stratified, Multi-arm, Multi-stage Factorial Randomised Platform Trial Aiming to Reduce the Incidence of Post-operative Surgical Site Infection (SSI).","MARLIN","Inclusion Criteria:\n\n* Patients with at least one abdominal incision that is ≥5cm (open or laparoscopic extraction site), with an anticipated clean-contaminated, contaminated, or dirty surgical wound. Definitions and examples of contamination are given in Table 1.\n* Patients undergoing emergency (surgery on an unplanned admission) or elective (surgery on a planned admission) operations.\n* Any operative indication for abdominal surgery (excluding caesarean section; see exclusion criteria).\n* Patient able and willing to provide written informed consent (signature or a fingerprint) prior to surgery (including emergency cases).\n* Patients aged 5 years and over. (This criteria MUST be made country-specific. Each country will decide the lower (and upper, if applicable according to local regulations age limit for the trial. This will be dependent on country-specific regulatory approvals. Age eligibility will vary by country.)\n\nExclusion Criteria:\n\n* Patient unable to complete post-operative follow-up (i.e., will not be contactable after discharge).\n* Patients undergoing clean surgical procedures.\n* Patients undergoing an obstetrics procedure, including caesarean sections.","ALL","5 Years",{"count":201,"type":202},10092,"ESTIMATED","INTERVENTIONAL",[205],"NA","MARLIN is a stratified, multi-arm, multi-stage factorial randomised platform trial aiming to reduce the incidence of post-operative surgical site infection (SSI).",[208],"Surgical Site Infection",[210,211,212,213],"surgery","global surgery","SSI","surgical site infection","NOT_YET_RECRUITING","2024-06-18",{"date":217,"type":218},"2024-06-20","ACTUAL",{"date":220,"type":202},"2024-09-01",{"date":222,"type":202},"2026-09-30",{"name":5,"class":6},7]