[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100571189":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":18,"centralContacts":25,"locations":31,"responsibleParty":46,"collaborators":48,"id":78,"slug":79,"hasResults":80,"nctId":81,"briefTitle":82,"officialTitle":83,"acronym":18,"eligibilityCriteria":84,"healthyVolunteers":80,"sex":85,"minAge":86,"maxAge":87,"enrollmentInfo":88,"targetDuration":18,"studyType":91,"phases":92,"briefSummary":94,"conditions":95,"keywords":100,"overallStatus":107,"whyStopped":18,"lastUpdateSubmitDate":108,"lastUpdatePostDateStruct":109,"startDateStruct":112,"completionDateStruct":114,"leadSponsor":116,"locationsCount":117},{"fullName":5,"class":6},"Tianjin Medical University Cancer Institute and Hospital","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"3D trial group","EXPERIMENTAL","The three-dimensional reconstruction data of patients will be synthesized according to renal enhanced CT\u002FMRI within 48 hours before surgery. The surgeon\u002Fresearcher will conduct surgical planning according to the results of the three-dimensional reconstruction and perform robot-assisted laparoscopic nephron sparing surgery.",[13],"Diagnostic Test: Preoperative three-dimensional reconstruction",{"label":15,"type":16,"description":17,"interventionNames":18},"Conventional group","NO_INTERVENTION","The patients will not undergo preoperative 3D reconstruction. The surgeon will arrange robot-assisted laparoscopic nephron sparing surgery according to routine CT\u002FMRI.",null,[20],{"type":21,"name":22,"description":23,"armGroupLabels":24,"otherNames":18},"DIAGNOSTIC_TEST","Preoperative three-dimensional reconstruction","On the basis of conventional CT\u002FMRI, the patient will undergo 3D reconstruction within 48 hours before surgery. The surgeon\u002Fresearcher will conduct surgical planning according to the results of the 3D reconstruction and perform robot-assisted laparoscopic nephron sparing surgery.",[9],[26],{"name":27,"role":28,"phone":29,"phoneExt":18,"email":30},"Xin Yao","CONTACT","86 18622221103","liaowf2011@163.com",[32],{"facility":5,"status":18,"city":33,"state":18,"zip":18,"country":34,"countryCode":35,"cosmosGeoPoint":36,"geoPoint":41,"contacts":42},"Tianjin","China","CN",{"type":37,"coordinates":38},"Point",[39,40],117.17667,39.14222,{"lat":40,"lon":39},[43,44],{"name":27,"role":28,"phone":29,"phoneExt":18,"email":30},{"name":27,"role":45,"phone":18,"phoneExt":18,"email":18},"PRINCIPAL_INVESTIGATOR",{"type":47,"investigatorFullName":18,"investigatorTitle":18,"investigatorAffiliation":18,"oldNameTitle":18,"oldOrganization":18},"SPONSOR",[49,51,53,55,57,59,61,63,65,67,69,71,74,76],{"name":50,"class":6},"Sir Run Run Shaw Hospital",{"name":52,"class":6},"The First Affiliated Hospital of Zhengzhou University",{"name":54,"class":6},"Peking University First Hospital",{"name":56,"class":6},"Liaoning Cancer Hospital & Institute",{"name":58,"class":6},"The Second Affiliated Hospital of Dalian Medical University",{"name":60,"class":6},"First Affiliated Hospital of Chongqing Medical University",{"name":62,"class":6},"Qilu Hospital of Shandong University",{"name":64,"class":6},"Cangzhou Hospital of Integrated Traditional Chinese and Western Medicine",{"name":66,"class":6},"Hebei Medical University Fourth Hospital",{"name":68,"class":6},"West China Hospital",{"name":70,"class":6},"Tongji Hospital",{"name":72,"class":73},"Sun Yat-sen University Tumor Hospital","UNKNOWN",{"name":75,"class":6},"Shanghai Cancer Hospital, China",{"name":77,"class":6},"Shengjing Hospital","100571189","a-study-of-3d-visualization-techniques-to-improve-the-quality-and-safety-of-robot-assisted-nephron-sparing-surgery-for-complex-renal-tumors-100571189",false,"NCT06717009","A Study of 3D Visualization Techniques to Improve the Quality and Safety of Robot-assisted Nephron Sparing Surgery for Complex Renal Tumors.","A Prospective, Multicenter, Randomized Controlled Study of Three-dimensional Visualization Techniques to Improve the Quality and Safety of Robot-assisted Nephron Sparing Surgery for Complex Renal Tumors","Inclusion Criteria:\n\n1. The imaging diagnosis is single renal cell carcinoma, clinical stage is T1N0M0-T2N0M0, and the contralateral kidney function is good.\n2. Physical status and organ function allow robotic-assisted partial nephrectomy.\n3. Be able to adhere to the protocol during the study.\n4. The age ranges from 18 to 75 years, and there is no chronic kidney disease.\n5. KPS \\> 80; ECOG score: 0-1; There are no other serious concomitant diseases and the organ function is good.\n6. There are no medical contraindications seriously affecting anesthesia and surgery.\n7. The patient has no history of other malignant tumors in the past 5 years.\n8. There is no surgical history of epigastrium and the affected kidney.\n9. Estimated survival is more than 6 months, and there are no other severe diseases that reduce survival to less than 5 years.\n\nExclusion Criteria:\n\n1. Women who are pregnant or lactating, or who are of reproductive age and are not using effective contraception.\n2. Comorbid serious medical diseases or conditions, for example, clinically severe or active heart disease, severe uncontrolled medical illnesses and infections, severe uncontrolled digestive disorder, severe electrolyte disturbance, active disseminated intravascular coagulation, major organ failure such as decompensated cardiac, pulmonary, hepatic, or renal failure, symptomatic peripheral neuropathy. Can not tolerate robot-assisted laparoscopic partial nephrectomy\n3. Organ transplant recipients requiring immunosuppressive therapy.\n4. There is history of other malignancies within 5 years of trial initiation, excluding cured basal cell carcinoma of the skin and carcinoma in situ of the cervix.\n5. Patients who have received biological therapy or other anticancer traditional Chinese medicine within 4 weeks.\n6. Patients with multiple or bilateral renal tumors or solitary renal tumors.\n7. Patient without complete clinical information.","ALL","18 Years","75 Years",{"count":89,"type":90},350,"ESTIMATED","INTERVENTIONAL",[93],"NA","The goal of this clinical trial is to learn the evidence-based medical value of 3D visualization techniques to improve tumor control, preservation of renal function, and perioperative safety in robot-assisted nephron sparing surgery for complex renal tumors. The main question it aims to answer is:\n\nIs 3D visualization techniques more effective in improving robot-assisted nephron sparing surgery for complex renal tumors in terms of tumor control, renal function preservation, and perioperative safety.\n\nThe researchers will randomize participants into a 3D trial group and a conventional group for comparison.\n\nParticipants will:\n\nComplete Blood routine, liver and kidney function tests on the first and third day after operation.\n\nHave Renography at 3 and 12 months after the operation. Cooperate with follow-up visits.",[96,97,98,99],"Kidney Neoplasms \u002F Surgery","Robotic Surgical Procedures","Imaging, Three-Dimensional \u002F Methods","Nephrectomy \u002F Methods",[101,102,103,104,105,106],"Three-dimensional visualization technique;","Three-dimensional reconstruction","Robotic surgery","Kidney neoplasms","Laparoscopy","Nephron sparing surgery","NOT_YET_RECRUITING","2024-11-29",{"date":110,"type":111},"2024-12-04","ACTUAL",{"date":113,"type":90},"2025-01",{"date":115,"type":90},"2027-10",{"name":5,"class":6},1]