[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100631916":3},{"organization":4,"armGroups":7,"interventions":14,"overallOfficials":20,"centralContacts":21,"locations":31,"responsibleParty":47,"collaborators":20,"id":51,"slug":52,"hasResults":53,"nctId":54,"briefTitle":55,"officialTitle":56,"acronym":57,"eligibilityCriteria":58,"healthyVolunteers":53,"sex":59,"minAge":60,"maxAge":20,"enrollmentInfo":61,"targetDuration":20,"studyType":64,"phases":65,"briefSummary":67,"conditions":68,"keywords":70,"overallStatus":34,"whyStopped":20,"lastUpdateSubmitDate":74,"lastUpdatePostDateStruct":75,"startDateStruct":78,"completionDateStruct":80,"leadSponsor":82,"locationsCount":83},{"fullName":5,"class":6},"Rigshospitalet, Denmark","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"Daily online adaptive radiotherapy for head and neck cancer","EXPERIMENTAL","Patients will undergo daily online adaptive radiotherapy for all fractions in the treatment course. The treatment plan will be re-optimised following recontouring on a daily basis using the Siemens-Varian Ethos Platform.",[13],"Radiation: Daily online adaptive radiotherapy",[15],{"type":16,"name":17,"description":18,"armGroupLabels":19,"otherNames":20},"RADIATION","Daily online adaptive radiotherapy","The patients will undergo daily online adaptive re-optimisation of the radiotherapy treatment plan following daily recontouring.",[9],null,[22,27],{"name":23,"role":24,"phone":25,"phoneExt":20,"email":26},"Jeppe Friborg, MD, PhD","CONTACT","+45 35458189","jeppe.friborg@regionh.dk",{"name":28,"role":24,"phone":29,"phoneExt":20,"email":30},"Anne Lindegaard, MD","+45 35456107","anne.marie.mira.lindegaard@regionh.dk",[32],{"facility":33,"status":34,"city":35,"state":20,"zip":20,"country":36,"countryCode":37,"cosmosGeoPoint":38,"geoPoint":43,"contacts":44},"Rigshospitalet","RECRUITING","Copenhagen","Denmark","DK",{"type":39,"coordinates":40},"Point",[41,42],12.56553,55.67594,{"lat":42,"lon":41},[45,46],{"name":23,"role":24,"phone":25,"phoneExt":20,"email":26},{"name":28,"role":24,"phone":29,"phoneExt":20,"email":30},{"type":48,"investigatorFullName":49,"investigatorTitle":50,"investigatorAffiliation":5,"oldNameTitle":20,"oldOrganization":20},"PRINCIPAL_INVESTIGATOR","Jeppe Friborg","Consultant, MD","100631916","a-study-of-adaptive-radiotherapy-of-head-neck-cancer-using-daily-replanning-and-optimization-of-the-treatment-plan-100631916",false,"NCT07506902","A Study of Adaptive Radiotherapy of Head-neck Cancer Using Daily Replanning and Optimization of the Treatment Plan.","DART-HN - Daily Adaptive Radiotherapy of Head-neck Cancer.","DART-HN","Inclusion Criteria:\n\n* Patients with histologically proven squamous cell carcinoma of the pharynx or larynx planned for primary radiotherapy with curative intent No current or earlier malignancies, which may influence treatment, evaluation or outcome of the head-neck cancer Informed consent as required by law The patient cannot participate in conflicting protocols Stage I-IV (excluding T1-T2N0 carcinoma of the glottic larynx) ECOG\u002FWHO performance status 0-2\n\nExclusion Criteria:\n\nPatient with cancers of the glottic larynx (stage I\u002FII), skull base, sino-nasal area and unknown primary tumor.\n\nInability to attend full course of radiotherapy or follow-up visits in the outpatient clinic Distant metastasis Previous radiotherapy of the head and neck Previous surgery for the primary cancer with curative intent\n\n\\-","ALL","18 Years",{"count":62,"type":63},40,"ESTIMATED","INTERVENTIONAL",[66],"NA","Radiotherapy of head-neck cancer is associated with significant side effects. Using daily online adaptive radiotherapy to account for the changing anatomy, radiation to organs at risk can be lowered. We will investigate whether this is feasible and associated with a reduction in the risk of toxicity.",[69],"Head & Neck Squamous Cell Carcinoma",[71,72,73],"Head and neck cancer","Adaptive radiotherapy","Online adaptive radiotherapy","2026-03-26",{"date":76,"type":77},"2026-04-02","ACTUAL",{"date":79,"type":77},"2023-11-21",{"date":81,"type":63},"2028-12",{"name":5,"class":6},1]