[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100625297":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":29,"centralContacts":33,"locations":38,"responsibleParty":56,"collaborators":25,"id":59,"slug":60,"hasResults":61,"nctId":62,"briefTitle":63,"officialTitle":64,"acronym":25,"eligibilityCriteria":65,"healthyVolunteers":61,"sex":66,"minAge":67,"maxAge":25,"enrollmentInfo":68,"targetDuration":25,"studyType":71,"phases":72,"briefSummary":74,"conditions":75,"keywords":78,"overallStatus":41,"whyStopped":25,"lastUpdateSubmitDate":80,"lastUpdatePostDateStruct":81,"startDateStruct":84,"completionDateStruct":86,"leadSponsor":88,"locationsCount":89},{"fullName":5,"class":6},"Mayo Clinic","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Auricular transcutaneous vagus nerve stimulation","EXPERIMENTAL","The vagus nerve stimulation group will perform two sessions per day (morning and evening), each lasting approximately 30 minutes, for a total of 1 hour of auricular transcutaneous vagus nerve stimulation. This arm will continue using the active treatment for 8 weeks.",[13],"Other: Auricular transcutaneous vagus nerve stimulation",{"label":15,"type":16,"description":17,"interventionNames":18},"Sound sham electrodes","SHAM_COMPARATOR","The sham control group will will perform two sessions per day (morning and evening), each lasting approximately 30 minutes, for a total of 1 hour of daily stimulation using the sham device. After 4 weeks, the sham control group will begin active auricular transcutaneous vagus nerve stimulation for 4 weeks.",[19,13],"Other: Sham Device",[21,26],{"type":6,"name":22,"description":23,"armGroupLabels":24,"otherNames":25},"Sham Device","The sham control uses the same stimulation devices as the active group, but with modified electrodes that do not emit electrical current. Instead, they produce a mechanical vibration or clicking sensation that mimics the feeling of stimulation without delivering current to the skin.",[15],null,{"type":6,"name":9,"description":27,"armGroupLabels":28,"otherNames":25},"The Parasym AVNT is a noninvasive, transcutaneous auricular vagus nerve stimulator (tVNS) designed to deliver low-level electrical stimulation to the auricular branch of the vagus nerve through the skin of the outer ear.\n\nThe stimulator produces mild, pulsed electrical currents typically ranging from 0.1 to 5.0 milliampere (mA) at frequencies between 20-30 Hz and pulse widths of approximately 200-300 μs. The stimulation intensity is adjusted individually to produce a light tingling sensation without discomfort or visible muscle contraction.",[9,15],[30],{"name":31,"affiliation":5,"role":32},"Colton Clayton, Au.D., Ph.D.","PRINCIPAL_INVESTIGATOR",[34],{"name":31,"role":35,"phone":36,"phoneExt":25,"email":37},"CONTACT","904-953-2945","clayton.colton@mayo.edu",[39],{"facility":40,"status":41,"city":42,"state":43,"zip":44,"country":45,"countryCode":46,"cosmosGeoPoint":47,"geoPoint":52,"contacts":53},"Mayo Clinic in Florida","RECRUITING","Jacksonville","Florida","32224","United States","US",{"type":48,"coordinates":49},"Point",[50,51],-81.65565,30.33218,{"lat":51,"lon":50},[54,55],{"name":31,"role":35,"phone":25,"phoneExt":25,"email":25},{"name":31,"role":32,"phone":25,"phoneExt":25,"email":25},{"type":32,"investigatorFullName":57,"investigatorTitle":58,"investigatorAffiliation":5,"oldNameTitle":25,"oldOrganization":25},"Colton T. Clayton","Principal Investigator","100625297","a-study-of-auricular-transcutaneous-vagus-nerve-stimulation-in-chronic-dizziness-100625297",false,"NCT07420803","A Study Of Auricular Transcutaneous Vagus Nerve Stimulation In Chronic Dizziness","Efficacy Of Auricular Transcutaneous Vagus Nerve Stimulation In Treating Chronic Dizziness","Inclusion Criteria:\n\n* Age 18-75, Persistent Postural-Perceptual Dizziness (PPPD) diagnosis per International Classification of Vestibular Disorders (ICVD).\n* Persistent dizziness ≥3 months and at least 1 dizziness exacerbation\u002Fday during 2-week run-in.\n* On stable medications\u002Ftherapy for ≥4 weeks prior to baseline (if any).\n\nExclusion Criteria:\n\n* Uncompensated peripheral\u002Fcentral vestibular deficit, sensory-afferent or cerebellar ataxia.\n* Cardiac disease (coronary disease, unstable arrhythmia), recurrent syncope (\\>1 in past 12 months).\n* Neck surgery, vagotomy, or any condition interfering with vagal stimulation.\n* Pregnancy.","ALL","18 Years",{"count":69,"type":70},60,"ESTIMATED","INTERVENTIONAL",[73],"NA","The purpose of this study is to measure the change in dizziness, as measured by change in Dizziness Handicap Inventory (DHI) score, following a 4-week treatment period with auricular transcutaneous vagus nerve stimulation (aTVNS).",[76,77],"Chronic Dizziness","Persistent Postural Perceptual Dizziness",[79],"Vagus Nerve Stimulation","2026-04-14",{"date":82,"type":83},"2026-04-17","ACTUAL",{"date":85,"type":83},"2026-03-23",{"date":87,"type":70},"2027-03",{"name":5,"class":6},1]