[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100577724":3},{"organization":4,"armGroups":7,"interventions":7,"overallOfficials":8,"centralContacts":12,"locations":18,"responsibleParty":36,"collaborators":7,"id":40,"slug":41,"hasResults":42,"nctId":43,"briefTitle":44,"officialTitle":45,"acronym":7,"eligibilityCriteria":46,"healthyVolunteers":42,"sex":47,"minAge":48,"maxAge":49,"enrollmentInfo":50,"targetDuration":53,"studyType":54,"phases":7,"briefSummary":55,"conditions":56,"keywords":58,"overallStatus":21,"whyStopped":7,"lastUpdateSubmitDate":64,"lastUpdatePostDateStruct":65,"startDateStruct":68,"completionDateStruct":70,"leadSponsor":72,"locationsCount":73},{"fullName":5,"class":6},"Ruijin Hospital","OTHER",null,[9],{"name":10,"affiliation":5,"role":11},"Zhengbin Zhu, MD, PhD","STUDY_CHAIR",[13],{"name":14,"role":15,"phone":16,"phoneExt":7,"email":17},"Wenli Zhang, MD","CONTACT","+86 (021)64370045","zwl11929@rjh.com.cn",[19],{"facility":20,"status":21,"city":22,"state":23,"zip":24,"country":25,"countryCode":26,"cosmosGeoPoint":27,"geoPoint":32,"contacts":33},"Ruijin hospital, Shanghai JiaoTong University School of Medicine","RECRUITING","Shanghai","Shanghai Municipality","200025","China","CN",{"type":28,"coordinates":29},"Point",[30,31],121.45806,31.22222,{"lat":31,"lon":30},[34],{"name":14,"role":15,"phone":35,"phoneExt":7,"email":17},"+86 64370045",{"type":37,"investigatorFullName":38,"investigatorTitle":39,"investigatorAffiliation":5,"oldNameTitle":7,"oldOrganization":7},"PRINCIPAL_INVESTIGATOR","Zhu zhengbin","deputy chief physician","100577724","a-study-of-chinese-congenital-bicuspid-aortic-valve-100577724",false,"NCT06802016","A Study of Chinese Congenital Bicuspid Aortic Valve","A Cohort Study of Congenital Bicuspid Aortic Valve","Inclusion Criteria:\n\n* The patients were aged 14-60 years;\n* Definitive diagnosis of BAV by imaging (echocardiography, aortic CTA, cardiac magnetic resonance, etc.)\n* Patients were informed about the nature of the study and agreed to participate in all the terms of the study and signed an informed consent form approved by the ethics committee.\n\nExclusion Criteria:\n\n* Poor patient compliance and inability to complete follow-up visits as required;\n* Rheumatic heart valve disease, other organic valve disease.\n* Hyperthyroidism, severe anemia, and other factors that significantly affect hemodynamics.\n* Other circumstances that the researcher believes should be excluded.","ALL","14 Years","60 Years",{"count":51,"type":52},500,"ESTIMATED","10 Years","OBSERVATIONAL","Pervious studies indicated that the prevalence of bicuspid aortic valve（BAV） might be higher in China. There is a familial predisposition to the development of BAV. The study analyzed epidemiological data on selected BAV and established a BAV cohort to observe disease progression and treatment outcomes.",[57],"Bicuspid Aortic Valve (BAV)",[59,60,61,62,63],"Bicuspid Aortic Valve","Dilated ascending aorta","Aortic regurgitation","Aortic stenosis","Acoustic cardiography","2025-01-30",{"date":66,"type":67},"2025-02-03","ACTUAL",{"date":69,"type":67},"2025-01-18",{"date":71,"type":52},"2035-12-31",{"name":5,"class":6},1]