[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100586016":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":31,"centralContacts":39,"locations":48,"responsibleParty":73,"collaborators":26,"id":76,"slug":77,"hasResults":78,"nctId":79,"briefTitle":80,"officialTitle":81,"acronym":82,"eligibilityCriteria":83,"healthyVolunteers":78,"sex":84,"minAge":85,"maxAge":86,"enrollmentInfo":87,"targetDuration":26,"studyType":90,"phases":91,"briefSummary":93,"conditions":94,"keywords":96,"overallStatus":50,"whyStopped":26,"lastUpdateSubmitDate":101,"lastUpdatePostDateStruct":102,"startDateStruct":105,"completionDateStruct":107,"leadSponsor":109,"locationsCount":110},{"fullName":5,"class":6},"Harokopio University","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Intervention group","EXPERIMENTAL","This arm will consume 600 mL of a sparkling beverage enriched with Chios mastic per day for a 3-month period.",[13],"Behavioral: Chios mastic beverage",{"label":15,"type":16,"description":17,"interventionNames":18},"Control group","PLACEBO_COMPARATOR","This arm will consume 600 mL of a standard sparkling beverage per day for a 3-month period.",[19],"Behavioral: Placebo beverage",[21,27],{"type":22,"name":23,"description":24,"armGroupLabels":25,"otherNames":26},"BEHAVIORAL","Chios mastic beverage","Participants of this intervention arm will be provided with a sparkling beverage enriched with the natural mastic aqueous extract (0.2%), a by-product of Chios mastic processing, and will be asked to consume it daily (3 bottles of 200 mL each) for 3 months. Participants will also be instructed to maintain their usual lifestyle practices and medical treatment stable.",[9],null,{"type":22,"name":28,"description":29,"armGroupLabels":30,"otherNames":26},"Placebo beverage","Participants of this intervention arm will be provided with a placebo sparkling beverage (same organoleptic characteristics with experimental beverage but no active ingredients) and will be asked to consume it daily (3 bottles of 200 mL each) for 3 months. Participants will also be instructed to maintain their usual lifestyle practices and medical treatment stable.",[15],[32,36],{"name":33,"affiliation":34,"role":35},"Giannis Arnaoutis, PhD","Department of Nutrition and Dietetics, School of Health Sciences and Education, Harokopio University of Athens","PRINCIPAL_INVESTIGATOR",{"name":37,"affiliation":34,"role":38},"Labros Sidossis, PhD","STUDY_DIRECTOR",[40,45],{"name":33,"role":41,"phone":42,"phoneExt":43,"email":44},"CONTACT","+302109549100","321","garn@hua.gr",{"name":46,"role":41,"phone":42,"phoneExt":43,"email":47},"Michael Georgoulis, PhD","mgeor@hua.gr",[49],{"facility":34,"status":50,"city":51,"state":52,"zip":53,"country":54,"countryCode":55,"cosmosGeoPoint":56,"geoPoint":61,"contacts":62},"RECRUITING","Kallithea","Attica","17676","Greece","GR",{"type":57,"coordinates":58},"Point",[59,60],23.7,37.95,{"lat":60,"lon":59},[63,64,65,66,68,69,71],{"name":33,"role":41,"phone":42,"phoneExt":43,"email":44},{"name":46,"role":41,"phone":42,"phoneExt":43,"email":47},{"name":33,"role":35,"phone":26,"phoneExt":26,"email":26},{"name":37,"role":67,"phone":26,"phoneExt":26,"email":26},"SUB_INVESTIGATOR",{"name":46,"role":67,"phone":26,"phoneExt":26,"email":26},{"name":70,"role":67,"phone":26,"phoneExt":26,"email":26},"Alexandra Karachaliou, PhD",{"name":72,"role":67,"phone":26,"phoneExt":26,"email":26},"Evripidis Rizos, MD, PhDc",{"type":35,"investigatorFullName":74,"investigatorTitle":75,"investigatorAffiliation":5,"oldNameTitle":26,"oldOrganization":26},"GIANNIS ARNAOUTIS","Assistant Professor","100586016","a-study-of-chios-mastic-water-in-dyspepsia-100586016",false,"NCT06909890","A Study of Chios Mastic Water in Dyspepsia","The Effectiveness of a Natural Aqueous Extract of Chios Mastic in the Management of Dyspepsia: the MASTIQUA-D Randomized Controlled Clinical Trial","MASTIQUA-D","Inclusion Criteria:\n\n* Age 30-60 years old.\n* Body mass index of 20-35 kg\u002Fm2.\n* Presence of dyspepsia.\n\nExclusion Criteria:\n\n* Presence of chronic diseases (e.g. diabetes mellitus, cancer, cardiovascular, hepatic, renal, respiratory, chronic inflammatory and psychiatric diseases).\n* Presence of other chronic gastrointestinal diseases (e.g. gastroesophageal reflux, inflammatory bowel disease and celiac disease).\n* Use of immunosuppressants, anti-inflammatories, antibiotics and corticosteroids.\n* Use of dietary supplements or other products with Chios mastic.\n* Excessive alcohol consumption (\\>210 g and \\>140 g of ethanol per week for men and women, respectively).\n* Currently on a weight-loss diet or recent (within 6 months) significant change in lifestyle habits.\n* Pregnancy or breast feeding (for women)","ALL","30 Years","60 Years",{"count":88,"type":89},60,"ESTIMATED","INTERVENTIONAL",[92],"NA","Chios mastic is a natural product with strong antimicrobial, anti-inflammatory and antioxidant properties, and well-established benefits for dyspeptic disorders. The aim of the present study is to investigate the effectiveness of a natural aqueous extract of Chios mastic (mastic water), a by-product of Chios mastic processing, in the management of dyspepsia. This will be a 3-month randomized double-blind controlled clinical trial in adults with dyspepsia. Participants will be blindly randomized to an intervention group, which will receive 600 mL\u002Fd of a carbonated beverage enriched with Chios mastic water (0.2%), or a control group, which will receive 600 mL\u002Fd of an identical placebo beverage with no active ingredients. Participants will be evaluated in terms of anthropometric indices, lifestyle habits, severity of dyspepsia-related gastrointestinal symptoms, quality of life, as well as biochemical markers, both pre- and post-intervention.",[95],"Dyspepsia",[97,98,99,100],"Pistacia Lentiscus var. Chia","Chios mastic","dyspepsia","gastrointestinal health","2025-09-09",{"date":103,"type":104},"2025-09-15","ACTUAL",{"date":106,"type":104},"2025-07-10",{"date":108,"type":89},"2026-12",{"name":5,"class":6},1]